A helping hand to overcome solubility challenges in chemical protein synthesis MT Jacobsen, ME Petersen, X Ye, M Galibert, GH Lorimer, V Aucagne, ... Journal of the American Chemical Society 138 (36), 11775-11782, 2016 | 81 | 2016 |
Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogs in LNCaP and U937 cancer cell lines provides insight into their differential … N Kedei, A Telek, AM Michalowski, MB Kraft, W Li, YB Poudel, A Rudra, ... Biochemical pharmacology 85 (3), 313-324, 2013 | 23 | 2013 |
Synthesis of tumor necrosis factor α for use as a mirror-image phage display target ME Petersen, MT Jacobsen, MS Kay Organic & biomolecular chemistry 14 (23), 5298-5303, 2016 | 21 | 2016 |
Synthesis of hydrophobic insulin-based peptides using a helping hand strategy MM Disotuar, ME Petersen, JM Nogueira, MS Kay, DHC Chou Organic & biomolecular chemistry 17 (7), 1703-1708, 2019 | 20 | 2019 |
Synthetic ingenols maximize protein kinase C-induced HIV-1 latency reversal AM Spivak, RA Nell, M Petersen, L Martins, P Sebahar, RE Looper, ... Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01361-18, 2018 | 19 | 2018 |
Chemical synthesis of Shiga toxin subunit B using a next-generation traceless “helping hand” solubilizing tag JM Fulcher, ME Petersen, RJ Giesler, ZS Cruz, DM Eckert, JN Francis, ... Organic & biomolecular chemistry 17 (48), 10237-10244, 2019 | 15 | 2019 |
Biological activity of the bryostatin analog Merle 23 on mouse epidermal cells and mouse skin JS Kelsey, C Cataisson, J Chen, MA Herrmann, ME Petersen, ... Molecular carcinogenesis 55 (12), 2183-2195, 2016 | 8 | 2016 |
Generation and structure-activity relationships of novel imidazo-thienopyridine based TLR7 agonists: application as payloads for immunostimulatory antibody drug-conjugates MG Brant, GAE Garnett, J Guedia, M Lasalle, S Lawn, ME Petersen, ... Bioorganic & Medicinal Chemistry Letters 91, 129348, 2023 | 5 | 2023 |
Molecular systems pharmacology: isoelectric focusing signature of protein kinase Cδ provides an integrated measure of its modulation in response to ligands N Kedei, JQ Chen, MA Herrmann, A Telek, PK Goldsmith, ME Petersen, ... Journal of Medicinal Chemistry 57 (12), 5356-5369, 2014 | 5 | 2014 |
Replacement of the bryostatin A-and B-pyran rings with phenyl rings leads to loss of high affinity binding with PKC ME Petersen, N Kedei, NE Lewin, PM Blumberg, GE Keck Tetrahedron letters 57 (42), 4749-4753, 2016 | 4 | 2016 |
Synthesis and biological evaluation of fluorescent bryostatin analogues TJ Cummins, N Kedei, A Czikora, NE Lewin, S Kirk, ME Petersen, ... ChemBioChem 19 (8), 877-889, 2018 | 3 | 2018 |
Design and evaluation of ZD06519, a novel camptothecin payload for antibody drug conjugates ME Petersen, MG Brant, M Lasalle, S Das, R Duan, J Wong, T Ding, ... Molecular Cancer Therapeutics 23 (5), 606-618, 2024 | 1 | 2024 |
Structure–Activity Relationships of Bis-Intercalating Peptides and Their Application as Antibody–Drug Conjugate Payloads ME Petersen, MG Brant, M Lasalle, VKC Fung, AH Rojas, J Wong, S Das, ... Journal of Medicinal Chemistry 66 (12), 8288-8309, 2023 | 1 | 2023 |
Bryostatin analogs and use thereof as antiviral agents GE Keck, MB Kraft, AP Truong, CC Sanchez, W Li, JA Covel, D Welch, ... US Patent App. 15/503,495, 2017 | 1 | 2017 |
Synthesis of structurally simplified bryostatin analogues: Probing the underlying biology and progressing towards more ‘drug like’compounds ME Petersen Ph. D. Thesis, University of Utah, Salt Lake City, UT, 2014.[Google Scholar], 2014 | 1 | 2014 |
Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential … N Kedei, A Telek, AM Michalowski, MB Kraft, W Li, YB Poudel, A Rudra, ... Cancer Research 72 (8_Supplement), 3815-3815, 2012 | 1 | 2012 |
Development of three-dimensional cancer cell line spheroid models for the in vitro functional characterization of cytotoxic antibody-drug conjugates J Wong, AH Rojas, A Bissessur, LT Degefie, AP Sagoe-Wagner, S Das, ... Cancer Research 84 (6_Supplement), 3127-3127, 2024 | | 2024 |
ZW191-a FRα-targeting antibody drug conjugate with strong preclinical activity across multiple FRα-expressing indications S Lawn, AH Rojas, R Colombo, J Wong, K Wu, V Fung, M Lasalle, ... Cancer Research 84 (6_Supplement), 1862-1862, 2024 | | 2024 |
ZW251, a novel Glypican 3-targeting antibody drug conjugate bearing a topoisomerase I inhibitor payload L Madera, AH Rojas, R Colombo, A Wu, CL Piscitelli, D Urosev, ... Cancer Research 83 (7_Supplement), 2658-2658, 2023 | | 2023 |
ZW220, a novel NaPi2b-targeting antibody drug conjugate bearing a topoisomerase 1 inhibitor payload AH Rojas, J Wong, D Urosev, S Lawn, K Wu, S Konomura, M Lasalle, ... Cancer Research 83 (7_Supplement), 1533-1533, 2023 | | 2023 |