Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor PW Janes, SC Ley, AI Magee The Journal of cell biology 147 (2), 447-461, 1999 | 1007 | 1999 |
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans PW Janes, N Saha, WA Barton, MV Kolev, SH Wimmer-Kleikamp, ... Cell 123 (2), 291-304, 2005 | 590 | 2005 |
The role of lipid rafts in T cell antigen receptor (TCR) signalling PW Janes, SC Ley, AI Magee, PS Kabouridis Seminars in immunology 12 (1), 23-34, 2000 | 581 | 2000 |
Architecture of Eph receptor clusters JP Himanen, L Yermekbayeva, PW Janes, JR Walker, K Xu, L Atapattu, ... Proceedings of the National Academy of Sciences 107 (24), 10860-10865, 2010 | 315 | 2010 |
Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2. PW Janes, RJ Daly, RL Sutherland Oncogene 9 (12), 3601-3608, 1994 | 294 | 1994 |
Recruitment of Eph receptors into signaling clusters does not require ephrin contact SH Wimmer-Kleikamp, PW Janes, A Squire, PIH Bastiaens, M Lackmann The Journal of cell biology 164 (5), 661-666, 2004 | 180 | 2004 |
Expression of c‐erbB receptors, heregulin and oestrogen receptor in human breast cell lines A DeFazio, YE Chiew, RL Sini, PW Janes, RL Sutherland International journal of cancer 87 (4), 487-498, 2000 | 177 | 2000 |
Stress-induced decrease in TRAF2 stability is mediated by Siah2 H Habelhah, IJ Frew, A Laine, PW Janes, F Relaix, D Sassoon, ... The EMBO journal 21 (21), 5756-5765, 2002 | 166 | 2002 |
Cloning and Characterization of GRB14, a Novel Member of the GRB7 Gene Family (∗) RJ Daly, GM Sanderson, PW Janes, RL Sutherland Journal of Biological Chemistry 271 (21), 12502-12510, 1996 | 154 | 1996 |
Structural basis for regulated proteolysis by the α-secretase ADAM10 TCM Seegar, LB Killingsworth, N Saha, PA Meyer, D Patra, B Zimmerman, ... Cell 171 (7), 1638-1648. e7, 2017 | 151 | 2017 |
Concepts and consequences of Eph receptor clustering PW Janes, E Nievergall, M Lackmann Seminars in cell & developmental biology 23 (1), 43-50, 2012 | 131 | 2012 |
Eph-dependent cell-cell adhesion and segregation in development and cancer E Nievergall, M Lackmann, PW Janes Cellular and Molecular Life Sciences 69, 1813-1842, 2012 | 122 | 2012 |
Generation and Analysis of Siah2 Mutant Mice IJ Frew, VE Hammond, RA Dickins, JMW Quinn, CR Walkley, NA Sims, ... Molecular and cellular biology 23 (24), 9150-9161, 2003 | 122 | 2003 |
Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors PW Janes, B Griesshaber, L Atapattu, E Nievergall, LL Hii, A Mensinga, ... Journal of Cell Biology 195 (6), 1033-1045, 2011 | 118 | 2011 |
Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3 RJ Fiddes, DH Campbell, PW Janes, SP Sivertsen, H Sasaki, C Wallasch, ... Journal of Biological Chemistry 273 (13), 7717-7724, 1998 | 113 | 1998 |
Eph receptor signalling: from catalytic to non-catalytic functions LY Liang, O Patel, PW Janes, JM Murphy, IS Lucet Oncogene 38 (39), 6567-6584, 2019 | 112 | 2019 |
Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7 PW Janes, M Lackmann, WB Church, GM Sanderson, RL Sutherland, ... Journal of biological chemistry 272 (13), 8490-8497, 1997 | 112 | 1997 |
Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10 PW Janes, SH Wimmer-Kleikamp, AS Frangakis, K Treble, B Griesshaber, ... PLoS biology 7 (10), e1000215, 2009 | 110 | 2009 |
Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells RJ Fiddes, PW Janes, SP Sivertsen, RL Sutherland, EA Musgrove, ... Oncogene 16 (21), 2803-2813, 1998 | 98 | 1998 |
Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironment ME Vail, C Murone, A Tan, L Hii, D Abebe, PW Janes, FT Lee, M Baer, ... Cancer research 74 (16), 4470-4481, 2014 | 90 | 2014 |