关注
Qian Zhang
标题
引用次数
引用次数
年份
HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity
S Wu, Q Zhang, F Zhang, F Meng, S Liu, R Zhou, Q Wu, X Li, LI Shen, ...
Nature cell biology 21 (8), 1027-1040, 2019
1802019
Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade
Q Zhang, F Meng, S Chen, SW Plouffe, S Wu, S Liu, X Li, R Zhou, J Wang, ...
Nature cell biology 19 (4), 362-374, 2017
1742017
A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis
D Zhang, Y Liu, Y Zhu, Q Zhang, H Guan, S Liu, S Chen, C Mei, C Chen, ...
Nature cell biology 24 (5), 766-782, 2022
1112022
Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation
F Meng, R Zhou, S Wu, Q Zhang, Q Jin, Y Zhou, SW Plouffe, S Liu, ...
Genes & Development 30 (9), 1086-1100, 2016
832016
Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling
P Xu, S Bailey-Bucktrout, Y Xi, D Xu, D Du, Q Zhang, W Xiang, J Liu, ...
Molecular cell 56 (6), 723-737, 2014
812014
TBK1, a central kinase in innate immune sensing of nucleic acids and beyond
R Zhou, Q Zhang, P Xu
Acta biochimica et biophysica Sinica 52 (7), 757-767, 2020
662020
Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
F Meng, Z Yu, D Zhang, S Chen, H Guan, R Zhou, Q Wu, Q Zhang, S Liu, ...
Molecular Cell 81 (20), 4147-4164. e7, 2021
622021
PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1
W Xiang, Q Zhang, X Lin, S Wu, Y Zhou, F Meng, Y Fan, T Shen, M Xiao, ...
Science Advances 2 (7), e1501889, 2016
622016
TBK1-mediated DRP1 targeting confers nucleic acid sensing to reprogram mitochondrial dynamics and physiology
S Chen, S Liu, J Wang, Q Wu, A Wang, H Guan, Q Zhang, D Zhang, ...
Molecular Cell 80 (5), 810-827. e7, 2020
422020
Lck/Hck/Fgr-mediated tyrosine phosphorylation negatively regulates TBK1 to restrain innate antiviral responses
S Liu, S Chen, X Li, S Wu, Q Zhang, Q Jin, L Hu, R Zhou, Z Yu, F Meng, ...
Cell host & microbe 21 (6), 754-768. e5, 2017
392017
AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
Q Zhang, S Liu, CS Zhang, Q Wu, X Yu, R Zhou, F Meng, A Wang, ...
Molecular Cell 82 (23), 4519-4536. e7, 2022
202022
Chemical regulation of the cGAS-STING pathway
Q Zhang, C Chen, B Xia, P Xu
Current Opinion in Chemical Biology 69, 102170, 2022
152022
The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration
R Zhou, Q Wu, M Wang, S Irani, X Li, Q Zhang, F Meng, S Liu, F Zhang, ...
PLoS Biology 19 (2), e3001122, 2021
152021
The Hippo pathway in innate anti-microbial immunity and anti-tumor immunity
Q Zhang, R Zhou, P Xu
Frontiers in Immunology 11, 1473, 2020
122020
Targeting proteostasis of the HEV replicase to combat infection in preclinical models
F Zhang, LD Xu, Q Zhang, A Wang, X Yu, S Liu, C Chen, S Wu, J Jin, ...
Journal of Hepatology 78 (4), 704-716, 2023
112023
IRF3 activates RB to authorize cGAS-STING–induced senescence and mitigate liver fibrosis
Q Wu, X Leng, Q Zhang, YZ Zhu, R Zhou, Y Liu, C Mei, D Zhang, S Liu, ...
Science Advances 10 (9), eadj2102, 2024
32024
Interplay of MPP5a with Rab11 synergistically builds epithelial apical polarity and zonula adherens
Y Hao, Y Zhou, Y Yu, M Zheng, K Weng, Z Kou, J Liang, Q Zhang, X Tang, ...
Development 147 (22), dev184457, 2020
22020
Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells
SB Panina, JV Schweer, Q Zhang, G Raina, HA Hardtke, S Kim, W Yang, ...
BMC biology 22 (1), 83, 2024
2024
Variation of C-terminal domain governs RNA polymerase II genomic locations and alternative splicing in eukaryotic transcription
Q Zhang, W Kim, S Panina, JE Mayfield, B Portz, YJ Zhang
bioRxiv, 2024
2024
系统目前无法执行此操作,请稍后再试。
文章 1–19