An integrated framework advancing membrane protein modeling and design RF Alford, J Koehler Leman, BD Weitzner, AM Duran, DC Tilley, A Elazar, ... PLoS computational biology 11 (9), e1004398, 2015 | 174 | 2015 |
Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane A Elazar, J Weinstein, I Biran, Y Fridman, E Bibi, SJ Fleishman Elife 5, e12125, 2016 | 80 | 2016 |
Interplay between hydrophobicity and the positive-inside rule in determining membrane-protein topology A Elazar, JJ Weinstein, J Prilusky, SJ Fleishman Proceedings of the National Academy of Sciences 113 (37), 10340-10345, 2016 | 53 | 2016 |
A lipophilicity-based energy function for membrane-protein modelling and design JY Weinstein, A Elazar, SJ Fleishman PLoS computational biology 15 (8), e1007318, 2019 | 35 | 2019 |
De novo-designed transmembrane domains tune engineered receptor functions A Elazar, NJ Chandler, AS Davey, JY Weinstein, JV Nguyen, R Trenker, ... Elife 11, e75660, 2022 | 34 | 2022 |
Chance and pleiotropy dominate genetic diversity in complex bacterial environments L Noda-Garcia, D Davidi, E Korenblum, A Elazar, E Putintseva, A Aharoni, ... Nature Microbiology 4 (7), 1221-1230, 2019 | 21 | 2019 |
De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release A Elazar, NJ Chandler, AS Davey, JY Weinstein, JV Nguyen, R Trenker, ... bioRxiv, 2020.07. 26.221598, 2020 | 4 | 2020 |
Computational design of BclxL inhibitors that target transmembrane domain interactions G Duart, A Elazar, JY Weinstein, L Gadea-Salom, J Ortiz-Mateu, ... Proceedings of the National Academy of Sciences 120 (11), e2219648120, 2023 | 3 | 2023 |
DESIGNER CAR TRANSMEMBRANE DOMAINS PROVIDE PREDICTABLY TUNABLE T CELL FUNCTIONAL POTENCY M Call, A Elazar, N Chandler, A Davey, J Weinstein, R Trenker, J Nguyen, ... HUMAN GENE THERAPY 34 (21-22), A29-A29, 2023 | | 2023 |
De-novo designed transmembrane polypeptides and their uses in cellular immunotherapy S Fleishman, A Elazar, JY Weinstein, NJ CHANDLER US Patent App. 17/986,080, 2023 | | 2023 |
Deciphering membrane protein energetics using deep sequencing; Towards robust design and structure prediction of membrane proteins A Elazar, J Weinstein, S Fleishman Biophysical Journal 112 (3), 85a, 2017 | | 2017 |