| Functional characterization of rat brain-specific organic anion transporter (Oatp14) at the blood-brain barrier: high affinity transporter for thyroxine D Sugiyama, H Kusuhara, H Taniguchi, S Ishikawa, Y Nozaki, ... Journal of Biological Chemistry 278 (44), 43489-43495, 2003 | 336 | 2003 |
| Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin M Hirano, K Maeda, S Matsushima, Y Nozaki, H Kusuhara, Y Sugiyama Molecular pharmacology 68 (3), 800-807, 2005 | 314 | 2005 |
| Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices Y Nozaki, H Kusuhara, T Kondo, M Iwaki, Y Shiroyanagi, H Nakayama, ... Journal of Pharmacology and Experimental Therapeutics 322 (3), 1162-1170, 2007 | 164 | 2007 |
| Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions S Izumi, Y Nozaki, K Maeda, T Komori, O Takenaka, H Kusuhara, ... Drug Metabolism and Disposition 43 (2), 235-247, 2015 | 154 | 2015 |
| Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices Y Nozaki, H Kusuhara, T Kondo, M Hasegawa, Y Shiroyanagi, ... Journal of Pharmacology and Experimental Therapeutics 321 (1), 362-369, 2007 | 122 | 2007 |
| Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17β-glucuronide, estrone-3 … S Izumi, Y Nozaki, T Komori, K Maeda, O Takenaka, K Kusano, ... Drug Metabolism and Disposition 41 (10), 1859-1866, 2013 | 107 | 2013 |
| Quantitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of … Y Nozaki, H Kusuhara, H Endou, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 309 (1), 226-234, 2004 | 92 | 2004 |
| Investigation of fluorescein derivatives as substrates of organic anion transporting polypeptide (OATP) 1B1 to develop sensitive fluorescence-based OATP1B1 inhibition assays S Izumi, Y Nozaki, T Komori, O Takenaka, K Maeda, H Kusuhara, ... Molecular pharmaceutics 13 (2), 438-448, 2016 | 59 | 2016 |
| Comparison of the predictability of human hepatic clearance for organic anion transporting polypeptide substrate drugs between different in vitro–in vivo extrapolation approaches S Izumi, Y Nozaki, T Komori, O Takenaka, K Maeda, H Kusuhara, ... Journal of pharmaceutical sciences 106 (9), 2678-2687, 2017 | 48 | 2017 |
| Expression and Functional Involvement of Organic Anion Transporting Polypeptide Subtype 3 (Slc21a7) in Rat Choroid Plexus H Kusuhara, Z He, Y Nagata, Y Nozaki, T Ito, H Masuda, PJ Meier, T Abe, ... Pharmaceutical research 20, 720-727, 2003 | 41 | 2003 |
| Relative activity factor (RAF)-based scaling of uptake clearance mediated by organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 in human hepatocytes S Izumi, Y Nozaki, H Kusuhara, K Hotta, T Mochizuki, T Komori, K Maeda, ... Molecular pharmaceutics 15 (6), 2277-2288, 2018 | 39 | 2018 |
| Utility of cerebrospinal fluid drug concentration as a surrogate for unbound brain concentration in nonhuman primates Y Nagaya, Y Nozaki, K Kobayashi, O Takenaka, Y Nakatani, K Kusano, ... Drug Metabolism and Pharmacokinetics 29 (5), 419-426, 2014 | 36 | 2014 |
| Functional involvement of rat organic anion transporter 2 (Slc22a7) in the hepatic uptake of the nonsteroidal anti-inflammatory drug ketoprofen N Morita, H Kusuhara, Y Nozaki, H Endou, Y Sugiyama Drug metabolism and disposition 33 (8), 1151-1157, 2005 | 26 | 2005 |
| Alteration in the plasma concentrations of endogenous organic anion–transporting polypeptide 1B biomarkers in patients with non–small cell lung cancer treated with paclitaxel D Mori, H Ishida, T Mizuno, S Kusumoto, Y Kondo, S Izumi, G Nakata, ... Drug Metabolism and Disposition 48 (5), 387-394, 2020 | 21 | 2020 |
| Recent advances in preclinical in vitro approaches towards quantitative prediction of hepatic clearance and drug-drug interactions involving organic anion transporting … Y Nozaki, S Izumi Drug Metabolism and Pharmacokinetics 35 (1), 56-70, 2020 | 21 | 2020 |
| Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal … Y Nagaya, Y Nozaki, O Takenaka, R Watari, K Kusano, T Yoshimura, ... Drug Metabolism and Pharmacokinetics 31 (1), 57-66, 2016 | 16 | 2016 |
| Functional investigation of solute carrier family 35, member F2, in three cellular models of the primate blood-brain barrier T Mochizuki, T Mizuno, T Kurosawa, T Yamaguchi, K Higuchi, Y Tega, ... Drug Metabolism and Disposition 49 (1), 3-11, 2021 | 15 | 2021 |
| Experimental and modeling evidence supporting the trans-inhibition mechanism for preincubation time-dependent, long-lasting inhibition of organic anion transporting polypeptide … S Izumi, Y Nozaki, W Lee, Y Sugiyama Drug Metabolism and Disposition 50 (5), 541-551, 2022 | 13 | 2022 |
| Impact of P-glycoprotein–mediated active efflux on drug distribution into lumbar cerebrospinal fluid in nonhuman primates Y Nagaya, K Katayama, H Kusuhara, Y Nozaki Drug Metabolism and Disposition 48 (11), 1183-1190, 2020 | 10 | 2020 |
| Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and … K Kanamitsu, Y Nozaki, Y Nagaya, Y Sugiyama, H Kusuhara Drug Metabolism and Pharmacokinetics 32 (2), 135-144, 2017 | 8 | 2017 |
Kazuya MaedaKitasato University School of Pharmacy在 pharm.kitasato-u.ac.jp 的电子邮件经过验证
Kazuya MaedaKitasato University School of Pharmacy在 pharm.kitasato-u.ac.jp 的电子邮件经过验证