Improving polygenic prediction in ancestrally diverse populations Y Ruan, YF Lin, YCA Feng, CY Chen, M Lam, Z Guo, L He, A Sawa, ... Nature genetics 54 (5), 573-580, 2022 | 308 | 2022 |
Comparative genome analysis of Prevotella intermedia strain isolated from infected root canal reveals features related to pathogenicity and adaptation Y Ruan, L Shen, Y Zou, Z Qi, J Yin, J Jiang, L Guo, L He, Z Chen, Z Tang, ... BMC genomics 16, 1-21, 2015 | 53 | 2015 |
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ... Nature Medicine 29 (7), 1793-1803, 2023 | 49 | 2023 |
PRSet: Pathway-based polygenic risk score analyses and software SW Choi, J García-González, Y Ruan, HM Wu, C Porras, J Johnson, ... PLoS genetics 19 (2), e1010624, 2023 | 33 | 2023 |
Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients XZSQ Yunfeng Ruan, Jie Jiang, Liang Guo, Yan Li, Hailiang Huang, Lu Shen ... Scientific Reports 6 (doi:10.1038/srep23368), 2016 | 22 | 2016 |
The power of pathway-based polygenic risk scores SW Choi, J Garcia-Gonzalez, Y Ruan, HM Wu, J Johnson, C Hoggart, ... | 17* | 2021 |
An Engineered Rare Codon Device for Optimization of Metabolic Pathways LHGM You Wang, Chunying Li, Md. Rezaul Islam Khan, Yushu Wang, Yunfeng Ruan ... Scientific Reports 6, 2016 | 16 | 2016 |
Measured blood pressure, genetically predicted blood pressure, and cardiovascular disease risk in the UK biobank SMJ Cho, S Koyama, Y Ruan, K Lannery, M Wong, E Ajufo, H Lee, ... JAMA cardiology 7 (11), 1129-1137, 2022 | 15* | 2022 |
Genetic modification of inflammation-and clonal hematopoiesis–associated cardiovascular risk Z Yu, TP Fidler, Y Ruan, C Vlasschaert, T Nakao, MM Uddin, T Mack, ... The Journal of Clinical Investigation 133 (18), 2023 | 13 | 2023 |
Genetic association of drug response to erlotinib in Chinese advanced non-small cell lung cancer patients C Wang, F Chen, Y Liu, Q Xu, L Guo, X Zhang, Y Ruan, Y Shi, L Shen, ... Frontiers in pharmacology 9, 360, 2018 | 12 | 2018 |
Functional characterization of human CYP2C9 allelic variants in COS-7 cells H Du, Z Wei, Y Yan, Y Xiong, X Zhang, L Shen, Y Ruan, X Wu, Q Xu, L He, ... Frontiers in pharmacology 7, 98, 2016 | 12 | 2016 |
Improving polygenic prediction in ancestrally diverse populations. medRxiv (2021) Y Ruan, Y Anne Feng, C Chen, M Lam, A Sawa, A Martin Google Scholar, 0 | 9 | |
Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases B Truong, LE Hull, Y Ruan, QQ Huang, W Hornsby, H Martin, ... Cell Genomics 4 (4), 2024 | 8 | 2024 |
the Million Veteran Program AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ... A multi-ancestry polygenic risk score improves risk prediction for coronary …, 2023 | 6 | 2023 |
p. E95K mutation in Indian hedgehog causing brachydactyly type A1 impairs IHH/Gli1 downstream transcriptional regulation L Shen, G Ma, Y Shi, Y Ruan, X Yang, X Wu, Y Xiong, C Wan, C Yang, ... BMC genetics 20, 1-9, 2019 | 6 | 2019 |
Bipolar Disorder Working group of the Psychiatric Genomics C, Hoggart CJ SW Choi, J Garcia-Gonzalez, Y Ruan, HM Wu, C Porras, J Johnson O’Reilly PF. PRSet: pathway-based polygenic risk score analyses and software …, 2023 | 5 | 2023 |
Improving polygenic prediction in ancestrally diverse populations. medRxiv 2020.12. 27.20248738 Y Ruan, YCA Feng, CY Chen, M Lam, S Global, A Initiatives, A Sawa, ... | 5 | 2021 |
Polygenic score informed by genome-wide association studies of multiple ancestries and related traits improves risk prediction for coronary artery disease AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ... MedRxiv, 2023.03. 03.23286649, 2023 | 4 | 2023 |
Author correction: improving polygenic prediction in ancestrally diverse populations Y Ruan, YF Lin, YCA Feng, CY Chen, M Lam, Z Guo, L He, A Sawa, ... Nature Genetics 54 (8), 1259-1259, 2022 | 4 | 2022 |
Birth weight is associated with clonal hematopoiesis of indeterminate potential and cardiovascular outcomes in adulthood A Schuermans, T Nakao, Y Ruan, S Koyama, Z Yu, MM Uddin, ... Journal of the American Heart Association 12 (13), e030220, 2023 | 3 | 2023 |