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Pei Xin Lim
Pei Xin Lim
在 mskcc.org 的电子邮件经过验证
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引用次数
引用次数
年份
Homology-directed repair and the role of BRCA1, BRCA2, and related proteins in genome integrity and cancer
CC Chen, W Feng, PX Lim, EM Kass, M Jasin
Annual review of cancer biology 2 (1), 313-336, 2018
2872018
Conditional Inactivation of the DNA Damage Response Gene Hus1 in Mouse Testis Reveals Separable Roles for Components of the RAD9-RAD1-HUS1 Complex …
AM Lyndaker, PX Lim, JM Mleczko, CE Diggins, JK Holloway, RJ Holmes, ...
PLoS genetics 9 (2), e1003320, 2013
652013
Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation
EM Kass, PX Lim, HR Helgadottir, ME Moynahan, M Jasin
Nature communications 7 (1), 13241, 2016
452016
Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
R Prakash, T Sandoval, F Morati, JA Zagelbaum, PX Lim, T White, ...
Nature communications 12 (1), 4255, 2021
382021
BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
PX Lim, M Zaman, W Feng, M Jasin
Molecular Cell 84 (3), 447-462. e10, 2024
242024
HUS1 regulates in vivo responses to genotoxic chemotherapies
G Balmus, PX Lim, A Oswald, KR Hume, A Cassano, J Pierre, A Hill, ...
Oncogene 35 (5), 662-669, 2016
202016
Rapid interrogation of cancer cell of origin through CRISPR editing
W Feng, Z Cao, PX Lim, H Zhao, H Luo, N Mao, YS Lee, AA Rivera, ...
Proceedings of the National Academy of Sciences 118 (32), e2110344118, 2021
172021
Genome protection by the 9-1-1 complex subunit HUS1 requires clamp formation, DNA contacts, and ATR signaling-independent effector functions
PX Lim, DR Patel, KE Poisson, M Basuita, C Tsai, AM Lyndaker, ...
Journal of Biological Chemistry 290 (24), 14826-14840, 2015
172015
Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system
S Datta, ME Bucks, D Koley, PX Lim, SN Savinov
Bioorganic & medicinal chemistry 18 (16), 6099-6108, 2010
132010
BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks
D Georgieva, N Wang, A Taglialatela, S Jerabek, CR Reczek, PX Lim, ...
Cell reports 43 (4), 2024
12024
Abstract A27: assessing somatic tumor-associated RAD51 mutations and screening for novel dominant-interfering RAD51 proteins
PX Lim, J Sutherland, R Noonan, A Dananberg, W Holloman, ...
Molecular Cancer Research 15 (4_Supplement), A27-A27, 2017
12017
Abstract IA014: BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
PX Lim, M Jasin
Cancer Research 84 (1_Supplement), IA014-IA014, 2024
2024
Assessing somatic tumor-associated RAD51 mutations and screening for novel dominant-interfering RAD51 proteins
PX Lim, J Sutherland, R Noonan, A Dananberg, W Holloman, ...
MOLECULAR CANCER RESEARCH 15, 2017
2017
Mechanistic Functions Of The 9-1-1 Complex Subunit Hus1 In The Maintenance Of Genomic Integrity
PX Lim
2015
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