Homology-directed repair and the role of BRCA1, BRCA2, and related proteins in genome integrity and cancer CC Chen, W Feng, PX Lim, EM Kass, M Jasin Annual review of cancer biology 2 (1), 313-336, 2018 | 287 | 2018 |
Conditional Inactivation of the DNA Damage Response Gene Hus1 in Mouse Testis Reveals Separable Roles for Components of the RAD9-RAD1-HUS1 Complex … AM Lyndaker, PX Lim, JM Mleczko, CE Diggins, JK Holloway, RJ Holmes, ... PLoS genetics 9 (2), e1003320, 2013 | 65 | 2013 |
Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation EM Kass, PX Lim, HR Helgadottir, ME Moynahan, M Jasin Nature communications 7 (1), 13241, 2016 | 45 | 2016 |
Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex R Prakash, T Sandoval, F Morati, JA Zagelbaum, PX Lim, T White, ... Nature communications 12 (1), 4255, 2021 | 38 | 2021 |
BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair PX Lim, M Zaman, W Feng, M Jasin Molecular Cell 84 (3), 447-462. e10, 2024 | 24 | 2024 |
HUS1 regulates in vivo responses to genotoxic chemotherapies G Balmus, PX Lim, A Oswald, KR Hume, A Cassano, J Pierre, A Hill, ... Oncogene 35 (5), 662-669, 2016 | 20 | 2016 |
Rapid interrogation of cancer cell of origin through CRISPR editing W Feng, Z Cao, PX Lim, H Zhao, H Luo, N Mao, YS Lee, AA Rivera, ... Proceedings of the National Academy of Sciences 118 (32), e2110344118, 2021 | 17 | 2021 |
Genome protection by the 9-1-1 complex subunit HUS1 requires clamp formation, DNA contacts, and ATR signaling-independent effector functions PX Lim, DR Patel, KE Poisson, M Basuita, C Tsai, AM Lyndaker, ... Journal of Biological Chemistry 290 (24), 14826-14840, 2015 | 17 | 2015 |
Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system S Datta, ME Bucks, D Koley, PX Lim, SN Savinov Bioorganic & medicinal chemistry 18 (16), 6099-6108, 2010 | 13 | 2010 |
BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks D Georgieva, N Wang, A Taglialatela, S Jerabek, CR Reczek, PX Lim, ... Cell reports 43 (4), 2024 | 1 | 2024 |
Abstract A27: assessing somatic tumor-associated RAD51 mutations and screening for novel dominant-interfering RAD51 proteins PX Lim, J Sutherland, R Noonan, A Dananberg, W Holloman, ... Molecular Cancer Research 15 (4_Supplement), A27-A27, 2017 | 1 | 2017 |
Abstract IA014: BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair PX Lim, M Jasin Cancer Research 84 (1_Supplement), IA014-IA014, 2024 | | 2024 |
Assessing somatic tumor-associated RAD51 mutations and screening for novel dominant-interfering RAD51 proteins PX Lim, J Sutherland, R Noonan, A Dananberg, W Holloman, ... MOLECULAR CANCER RESEARCH 15, 2017 | | 2017 |
Mechanistic Functions Of The 9-1-1 Complex Subunit Hus1 In The Maintenance Of Genomic Integrity PX Lim | | 2015 |