Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma PV Raninga, G Di Trapani, S Vuckovic, M Bhatia, KF Tonissen Oncotarget 6 (17), 15410, 2015 | 89 | 2015 |
CEP 55 is a determinant of cell fate during perturbed mitosis in breast cancer M Kalimutho, D Sinha, J Jeffery, K Nones, S Srihari, WC Fernando, ... EMBO molecular medicine 10 (9), e8566, 2018 | 73 | 2018 |
NF-κB–inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction SA Rushworth, KM Bowles, P Raninga, DJ MacEwan Cancer research 70 (7), 2973-2983, 2010 | 73 | 2010 |
Therapeutic cooperation between auranofin, a thioredoxin reductase inhibitor and anti‐PD‐L1 antibody for treatment of triple‐negative breast cancer PV Raninga, AC Lee, D Sinha, YY Shih, D Mittal, A Makhale, AL Bain, ... International journal of cancer 146 (1), 123-136, 2020 | 72 | 2020 |
The multifaceted roles of DJ-1 as an antioxidant PV Raninga, G Di Trapani, KF Tonissen DJ-1/PARK7 Protein: Parkinson’s Disease, Cancer and Oxidative Stress-Induced …, 2017 | 71 | 2017 |
Cross talk between two antioxidant systems, thioredoxin and DJ-1: consequences for cancer PV Raninga, G Di Trapani, KF Tonissen Oncoscience 1 (1), 95, 2014 | 70 | 2014 |
TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-кβ inhibition PV Raninga, G Di Trapani, S Vuckovic, KF Tonissen Cell Cycle 15 (4), 559-572, 2016 | 65 | 2016 |
RNA-binding protein NONO contributes to cancer cell growth and confers drug resistance as a theranostic target in TNBC SJ Kim, JS Ju, MH Kang, JE Won, YH Kim, PV Raninga, KK Khanna, ... Theranostics 10 (18), 7974, 2020 | 50 | 2020 |
Marizomib suppresses triple-negative breast cancer via proteasome and oxidative phosphorylation inhibition PV Raninga, A Lee, D Sinha, L Dong, KK Datta, X Lu, P Kalita-de Croft, ... Theranostics 10 (12), 5259, 2020 | 50 | 2020 |
Anticancer activity of a Gold (I) phosphine thioredoxin reductase inhibitor in multiple myeloma JH Sze, PV Raninga, K Nakamura, M Casey, KK Khanna, ... Redox Biology 28, 101310, 2020 | 48 | 2020 |
Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma PV Raninga, G Di Trapani, S Vuckovic, KF Tonissen Redox Biology 8, 175-185, 2016 | 45 | 2016 |
Cep55 overexpression promotes genomic instability and tumorigenesis in mice D Sinha, P Nag, D Nanayakkara, PHG Duijf, A Burgess, P Raninga, ... Communications biology 3 (1), 593, 2020 | 29 | 2020 |
CX-5461 enhances the efficacy of APR-246 via induction of DNA damage and replication stress in triple-negative breast cancer A Makhale, D Nanayakkara, P Raninga, KK Khanna, M Kalimutho International Journal of Molecular Sciences 22 (11), 5782, 2021 | 22 | 2021 |
Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer M Kalimutho, D Sinha, D Mittal, S Srihari, D Nanayakkara, S Shafique, ... Journal of Experimental & Clinical Cancer Research 38, 1-18, 2019 | 18 | 2019 |
Cross-talk between Bcr-abl and the thioredoxin system in chronic myeloid leukaemia: implications for CML treatment E Clapper, S Wang, PV Raninga, G Di Trapani, KF Tonissen Antioxidants 9 (3), 207, 2020 | 14 | 2020 |
Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma PV Raninga, Y He, KK Datta, X Lu, UR Maheshwari, P Venkat, C Mayoh, ... Molecular Therapy 31 (3), 729-743, 2023 | 13 | 2023 |
Targeted knockdown of DJ-1 induces multiple myeloma cell death via KLF6 upregulation PV Raninga, G Di Trapani, S Vuckovic, KF Tonissen Apoptosis 21, 1422-1437, 2016 | 13 | 2016 |
Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer EM Poursani, D Mercatelli, P Raninga, JL Bell, F Saletta, FV Kohane, ... Cell & Bioscience 13 (1), 132, 2023 | 8 | 2023 |
Expression of the thioredoxin system in an in vivo-like cancer cell environment upon auranofin treatment M Bhatia, CJ Lovitt, PV Raninga, VM Avery, G Di Trapani, KF Tonissen European Journal of Cell Biology 95 (10), 378-388, 2016 | 5 | 2016 |
A design of experiments screen reveals that Clostridium novyi-NT spore germinant sensing is stereoflexible for valine and its analogs A Sundaresan, M Le Ngoc, MU Wew, V Ramkumar, P Raninga, R Sum, ... Communications Biology 6 (1), 118, 2023 | 4 | 2023 |