Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1α I Mylonis, G Chachami, M Samiotaki, G Panayotou, E Paraskeva, ... Journal of Biological Chemistry 281 (44), 33095-33106, 2006 | 365 | 2006 |
Hypoxia-inducible factors and the regulation of lipid metabolism I Mylonis, G Simos, E Paraskeva Cells 8 (3), 214, 2019 | 242 | 2019 |
Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression I Mylonis, H Sembongi, C Befani, P Liakos, S Siniossoglou, G Simos Journal of cell science 125 (14), 3485-3493, 2012 | 192 | 2012 |
Serine‐arginine protein kinases: a small protein kinase family with a large cellular presence T Giannakouros, E Nikolakaki, I Mylonis, E Georgatsou The FEBS journal 278 (4), 570-586, 2011 | 178 | 2011 |
Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1α by MAPK I Mylonis, G Chachami, E Paraskeva, G Simos Journal of Biological Chemistry 283 (41), 27620-27627, 2008 | 141 | 2008 |
The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions I Mylonis, A Lakka, A Tsakalof, G Simos Biochemical and biophysical research communications 398 (1), 74-78, 2010 | 135 | 2010 |
Casein kinase 1 regulates human hypoxia-inducible factor HIF-1 A Kalousi, I Mylonis, AS Politou, G Chachami, E Paraskeva, G Simos Journal of cell science 123 (17), 2976-2986, 2010 | 123 | 2010 |
Flavonoids induce HIF-1α but impair its nuclear accumulation and activity A Triantafyllou, I Mylonis, G Simos, S Bonanou, A Tsakalof Free Radical Biology and Medicine 44 (4), 657-670, 2008 | 110 | 2008 |
Prognostic significance of hypoxia-inducible factor 1 alpha (HIF-1alpha) expression in serous ovarian cancer: an immunohistochemical study A Daponte, M Ioannou, I Mylonis, G Simos, M Minas, IE Messinis, ... BMC cancer 8, 1-10, 2008 | 97 | 2008 |
Temporal association of protamine 1 with the inner nuclear membrane protein lamin B receptor during spermiogenesis I Mylonis, V Drosou, S Brancorsini, E Nikolakaki, P Sassone-Corsi, ... Journal of Biological Chemistry 279 (12), 11626-11631, 2004 | 92 | 2004 |
Mortalin-mediated and ERK-controlled targeting of HIF-1α to mitochondria confers resistance to apoptosis under hypoxia I Mylonis, M Kourti, M Samiotaki, G Panayotou, G Simos Journal of cell science 130 (2), 466-479, 2017 | 91 | 2017 |
Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells C Befani, I Mylonis, IM Gkotinakou, P Georgoulias, CJ Hu, G Simos, ... The international journal of biochemistry & cell biology 45 (11), 2359-2368, 2013 | 70 | 2013 |
MgcRacGAP interacts with HIF-1α and regulates its transcriptional activity A Lyberopoulou, E Venieris, I Mylonis, G Chachami, I Pappas, G Simos, ... Cellular Physiology and Biochemistry 20 (6), 995-1006, 2007 | 67 | 2007 |
Expression of AGPAT2, an enzyme involved in the glycerophospholipid/triacylglycerol biosynthesis pathway, is directly regulated by HIF-1 and promotes survival and etoposide … EA Triantafyllou, E Georgatsou, I Mylonis, G Simos, E Paraskeva Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 62 | 2018 |
Hypoxia inducible factor-1alpha and vascular endothelial growth factor in biopsies of small cell lung carcinoma M Ioannou, R Papamichali, E Kouvaras, I Mylonis, D Vageli, T Kerenidou, ... Lung 187, 321-329, 2009 | 60 | 2009 |
Lamin B Receptor: Interplay between Structure, Function and Localization E Nikolakaki, I Mylonis, T Giannakouros Cells 6 (3), 28, 2017 | 57 | 2017 |
HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia A Karagiota, M Kourti, G Simos, I Mylonis Cellular and Molecular Life Sciences 76, 809-825, 2019 | 53 | 2019 |
TNFα induces expression of HIF‐1α mRNA and protein but inhibits hypoxic stimulation of HIF‐1 transcriptional activity in airway smooth muscle cells S Tsapournioti, I Mylonis, A Hatziefthimiou, MG Ioannou, R Stamatiou, ... Journal of cellular physiology 228 (8), 1745-1753, 2013 | 53 | 2013 |
CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation M Kourti, G Ikonomou, NN Giakoumakis, MA Rapsomaniki, U Landegren, ... Cellular signalling 27 (6), 1129-1140, 2015 | 49 | 2015 |
Protein kinase CK2 phosphorylates and activates the SR protein-specific kinase 1 I Mylonis, T Giannakouros Biochemical and biophysical research communications 301 (3), 650-656, 2003 | 49 | 2003 |