The mitochondrial ATP synthase is a shared drug target for aging and dementia J Goldberg, A Currais, M Prior, W Fischer, C Chiruta, E Ratliff, ... Aging cell 17 (2), e12715, 2018 | 145 | 2018 |
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease Q Chen, M Prior, R Dargusch, A Roberts, R Riek, C Eichmann, C Chiruta, ... PloS one 6 (12), e27865, 2011 | 135 | 2011 |
The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice M Prior, R Dargusch, JL Ehren, C Chiruta, D Schubert Alzheimer's Research & Therapy 5, 1-19, 2013 | 117 | 2013 |
Back to the future with phenotypic screening M Prior, C Chiruta, A Currais, J Goldberg, J Ramsey, R Dargusch, ... ACS Chemical Neuroscience 5 (7), 503-513, 2014 | 105 | 2014 |
Chemical modification of the multitarget neuroprotective compound fisetin C Chiruta, D Schubert, R Dargusch, P Maher Journal of Medicinal Chemistry 55 (1), 378-389, 2012 | 102 | 2012 |
3-(3H-imidazo [4, 5-B] pyridin-2-yl)-1H-pyrazolo [3, 4-C] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,546,185, 2017 | 86 | 2017 |
3-(3H-imidazo [4, 5-C] pyridin-2-yl)-1H-pyrazolo [3, 4-C] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,475,825, 2016 | 85 | 2016 |
3-(1h-imidazo [4, 5-C] pyridin-2-yl)-1h-pyrazolo [3, 4-C] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,540,398, 2017 | 84 | 2017 |
3-(1h-benzo [d] imidazol-2-yl)-1h-pyrazolo [3, 4-c] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,657,016, 2017 | 83 | 2017 |
2-(1H-indazol-3-yl)-1H-imidazo [4, 5-C] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,475,807, 2016 | 66 | 2016 |
3-(1H-imidazo[4,5-C]pyridin-2-YL)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof US Patent 9,493,487, 2016 | 66* | 2016 |
2-(1H-indazol-3-yl)-3H-imidazo [4, 5-B] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,738,638, 2017 | 65 | 2017 |
3-(3H-imidazo [4, 5-B] pyridin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,758,531, 2017 | 64 | 2017 |
Total synthesis of the marine alkaloid halichlorine: development and use of a general route to chiral piperidines D Liu, HP Acharya, M Yu, J Wang, VSC Yeh, S Kang, C Chiruta, ... The Journal of Organic Chemistry 74 (19), 7417-7428, 2009 | 58 | 2009 |
Screening and identification of neuroprotective compounds relevant to Alzheimer׳ s disease from medicinal plants of S. Tomé e Príncipe A Currais, C Chiruta, M Goujon-Svrzic, G Costa, T Santos, MT Batista, ... Journal of Ethnopharmacology 155 (1), 830-840, 2014 | 57 | 2014 |
3-(1H-imidazo [4, 5-C] pyridin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,889,140, 2018 | 49 | 2018 |
3-(1H-imidazo [4, 5-C] pyridin-2-yl)-1H-pyrazolo [3, 4-C] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,844,536, 2017 | 49 | 2017 |
3-(3H-imidazo [4, 5-B] pyridin-2-yl)-1H-pyrazolo [3, 4-C] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,815,854, 2017 | 49 | 2017 |
3-(3H-imidazo [4, 5-C] pyridin-2-yl)-1H-pyrazolo [3, 4-C] pyridine and therapeutic uses thereof SK KC, DM Wallace, J Cao, C Chiruta, J Hood US Patent 9,763,951, 2017 | 49 | 2017 |
The total synthesis of macrosphelides A and E from carbohydrate precursors GVM Sharma, CC Mouli Tetrahedron letters 43 (50), 9159-9161, 2002 | 46 | 2002 |