Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis E Oda, R Ohki, H Murasawa, J Nemoto, T Shibue, T Yamashita, T Tokino, ... Science 288 (5468), 1053-1058, 2000 | 2959 | 2000 |
EMT, CSCs, and drug resistance: the mechanistic link and clinical implications T Shibue, RA Weinberg Nature reviews Clinical oncology 14 (10), 611-629, 2017 | 2303 | 2017 |
Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence A Takaoka, S Hayakawa, H Yanai, D Stoiber, H Negishi, H Kikuchi, ... Nature 424 (6948), 516-523, 2003 | 1116 | 2003 |
Slug and Sox9 cooperatively determine the mammary stem cell state W Guo, Z Keckesova, JL Donaher, T Shibue, V Tischler, F Reinhardt, ... Cell 148 (5), 1015-1028, 2012 | 1097 | 2012 |
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells X Ye, WL Tam, T Shibue, Y Kaygusuz, F Reinhardt, E Ng Eaton, ... Nature 525 (7568), 256-260, 2015 | 746 | 2015 |
Integral role of Noxa in p53-mediated apoptotic response T Shibue, K Takeda, E Oda, H Tanaka, H Murasawa, A Takaoka, ... Genes & development 17 (18), 2233-2238, 2003 | 444 | 2003 |
Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs T Shibue, RA Weinberg Proceedings of the National Academy of Sciences 106 (25), 10290-10295, 2009 | 428 | 2009 |
WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature 568 (7753), 551-556, 2019 | 309 | 2019 |
The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions T Shibue, MW Brooks, MF Inan, F Reinhardt, RA Weinberg Cancer discovery 2 (8), 706-721, 2012 | 255 | 2012 |
An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonization T Shibue, MW Brooks, RA Weinberg Cancer cell 24 (4), 481-498, 2013 | 208 | 2013 |
Metastatic colonization: settlement, adaptation and propagation of tumor cells in a foreign tissue environment T Shibue, RA Weinberg Seminars in cancer biology 21 (2), 99-106, 2011 | 172 | 2011 |
Inflammation triggers Zeb1-dependent escape from tumor latency JM De Cock, T Shibue, A Dongre, Z Keckesova, F Reinhardt, ... Cancer research 76 (23), 6778-6784, 2016 | 144 | 2016 |
Differential contribution of Puma and Noxa in dual regulation of p53‐mediated apoptotic pathways T Shibue, S Suzuki, H Okamoto, H Yoshida, Y Ohba, A Takaoka, ... The EMBO journal 25 (20), 4952-4962, 2006 | 123 | 2006 |
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action JM McFarland, BR Paolella, A Warren, K Geiger-Schuller, T Shibue, ... Nature communications 11 (1), 4296, 2020 | 115 | 2020 |
Predicting cell health phenotypes using image-based morphology profiling GP Way, M Kost-Alimova, T Shibue, WF Harrington, S Gill, F Piccioni, ... Molecular biology of the cell 32 (9), 995-1005, 2021 | 102 | 2021 |
Global computational alignment of tumor and cell line transcriptional profiles A Warren, Y Chen, A Jones, T Shibue, WC Hahn, JS Boehm, F Vazquez, ... Nature communications 12 (1), 22, 2021 | 101 | 2021 |
The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming JJ Unternaehrer, R Zhao, K Kim, M Cesana, JT Powers, ... Stem cell reports 3 (5), 691-698, 2014 | 99 | 2014 |
Tumor necrosis factor α 5′‐flanking region, tumor necrosis factor receptor II, and HLA–DRB1 polymorphisms in Japanese patients with rheumatoid arthritis T Shibue, N Tsuchiya, T Komata, M Matsushita, M Shiota, J Ohashi, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2000 | 80 | 2000 |
BH3‐only proteins: Integrated control point of apoptosis T Shibue, T Taniguchi International journal of cancer 119 (9), 2036-2043, 2006 | 74 | 2006 |
Allele typing of human TNFA 5′‐flanking region using polymerase chain reaction‐preferential homoduplex formation assay (PCR‐PHFA): linkage disequilibrium … M Matsushita, N Tsuchiya, T Nakayama, J Ohashi, T Shibue, M Shiota, ... Tissue Antigens 54 (5), 478-484, 1999 | 55 | 1999 |