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| Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion R Atarashi, K Satoh, K Sano, T Fuse, N Yamaguchi, D Ishibashi, ... Nature medicine 17 (2), 175-178, 2011 | 640 | 2011 |
| Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays JM Wilham, CD Orrú, RA Bessen, R Atarashi, K Sano, B Race, ... PLoS pathogens 6 (12), e1001217, 2010 | 530 | 2010 |
| Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein R Atarashi, RA Moore, VL Sim, AG Hughson, DW Dorward, HA Onwubiko, ... Nature methods 4 (8), 645-650, 2007 | 405 | 2007 |
| Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking R Atarashi, JM Wilham, L Christensen, AG Hughson, RA Moore, ... Nature methods 5 (3), 211-212, 2008 | 377 | 2008 |
| A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination. N Nishida, P Tremblay, T Sugimoto, K Shigematsu, S Shirabe, ... Laboratory investigation; a journal of technical methods and pathology 79 (6 …, 1999 | 291 | 1999 |
| Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors JI Kim, I Cali, K Surewicz, Q Kong, GJ Raymond, R Atarashi, B Race, ... Journal of Biological Chemistry 285 (19), 14083-14087, 2010 | 269 | 2010 |
| Real-time quaking-induced conversion: a highly sensitive assay for prion detection R Atarashi, K Sano, K Satoh, N Nishida Prion 5 (3), 150-153, 2011 | 198 | 2011 |
| Early detection of abnormal prion protein in genetic human prion diseases now possible using real-time QUIC assay K Sano, K Satoh, R Atarashi, H Takashima, Y Iwasaki, M Yoshida, ... PloS one 8 (1), e54915, 2013 | 167 | 2013 |
| Cerebrospinal fluid real‐time quaking‐induced conversion is a robust and reliable test for sporadic creutzfeldt–jakob disease: An international study LI McGuire, A Poleggi, I Poggiolini, S Suardi, K Grznarova, S Shi, B de Vil, ... Annals of neurology 80 (1), 160-165, 2016 | 132 | 2016 |
| The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases M Schmitz, M Cramm, F Llorens, D Müller-Cramm, S Collins, R Atarashi, ... Nature protocols 11 (11), 2233-2242, 2016 | 130 | 2016 |
| Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to … A Li, S Sakaguchi, K Shigematsu, R Atarashi, BC Roy, R Nakaoke, ... The American journal of pathology 157 (5), 1447-1452, 2000 | 116 | 2000 |
| Cutting edge: Brucella abortus exploits a cellular prion protein on intestinal M cells as an invasive receptor G Nakato, K Hase, M Suzuki, M Kimura, M Ato, M Hanazato, M Tobiume, ... The Journal of Immunology 189 (4), 1540-1544, 2012 | 106 | 2012 |
| Distinct structures of scrapie prion protein (PrPSc)-seeded versus spontaneous recombinant prion protein fibrils revealed by hydrogen/deuterium exchange V Smirnovas, JI Kim, X Lu, R Atarashi, B Caughey, WK Surewicz Journal of Biological Chemistry 284 (36), 24233-24241, 2009 | 100 | 2009 |
| Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene A Li, S Sakaguchi, R Atarashi, BC Roy, R Nakaoke, K Arima, N Okimura, ... Cellular and molecular neurobiology 20, 553-567, 2000 | 96 | 2000 |
| FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice T Nakagaki, K Satoh, D Ishibashi, T Fuse, K Sano, YO Kamatari, K Kuwata, ... Autophagy 9 (9), 1386-1394, 2013 | 92 | 2013 |
| Prion protein is necessary for latent learning and long-term memory retention N Nishida, S Katamine, K Shigematsu, A Nakatani, N Sakamoto, ... Cellular and molecular neurobiology 17, 537-545, 1997 | 90 | 1997 |
| Prion-like seeding of misfolded α-synuclein in the brains of dementia with Lewy body patients in RT-QUIC K Sano, R Atarashi, K Satoh, D Ishibashi, T Nakagaki, Y Iwasaki, ... Molecular neurobiology 55, 3916-3930, 2018 | 88 | 2018 |
| Deletion of N-terminal residues 23–88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration R Atarashi, N Nishida, K Shigematsu, S Goto, T Kondo, S Sakaguchi, ... Journal of Biological Chemistry 278 (31), 28944-28949, 2003 | 76 | 2003 |
| Prion disease KJ Baldwin, CM Correll Seminars in neurology 39 (04), 428-439, 2019 | 68 | 2019 |
