Altered Xylem-Phloem Transfer of Amino Acids Affects Metabolism and Leads to Increased Seed Yield and Oil Content in Arabidopsis L Zhang, Q Tan, R Lee, A Trethewy, YH Lee, M Tegeder The Plant Cell 22 (11), 3603-3620, 2010 | 234 | 2010 |
RAS–MAPK–MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1 J Park, I Al-Ramahi, Q Tan, N Mollema, JR Diaz-Garcia, T Gallego-Flores, ... Nature 498 (7454), 325-331, 2013 | 156 | 2013 |
Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans HC Lu, Q Tan, MWC Rousseaux, W Wang, JY Kim, R Richman, YW Wan, ... Nature genetics 49 (4), 527-536, 2017 | 145 | 2017 |
ATXN1-CIC complex is the primary driver of cerebellar pathology in spinocerebellar ataxia type 1 through a gain-of-function mechanism MWC Rousseaux, T Tschumperlin, HC Lu, EP Lackey, VV Bondar, ... Neuron 97 (6), 1235-1243. e5, 2018 | 115 | 2018 |
Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models Q Tan, HK Yalamanchili, J Park, A De Maio, HC Lu, YW Wan, JJ White, ... Human molecular genetics 25 (23), 5083-5093, 2016 | 106 | 2016 |
Increased Phloem Transport of S-Methylmethionine Positively Affects Sulfur and Nitrogen Metabolism and Seed Development in Pea Plants Q Tan, L Zhang, J Grant, P Cooper, M Tegeder Plant Physiology 154 (4), 1886-1896, 2010 | 100 | 2010 |
Cloning and characterisation of the gene encoding HMG-CoA reductase from Taxus media and its functional identification in yeast Z Liao, Q Tan, Y Chai, K Zuo, M Chen, Y Gong, P Wang, Y Pi, F Tan, ... Functional plant biology 31 (1), 73-81, 2004 | 63 | 2004 |
Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma Q Tan, L Brunetti, MWC Rousseaux, HC Lu, YW Wan, JP Revelli, Z Liu, ... Proceedings of the National Academy of Sciences 115 (7), E1511-E1519, 2018 | 53 | 2018 |
Characterization and expression of French bean amino acid transporter PvAAP1 Q Tan, AK Grennan, HC Pélissier, D Rentsch, M Tegeder Plant Science 174 (3), 348-356, 2008 | 53 | 2008 |
Amino acid transporter expression and localisation studies in pea (Pisum sativum) M Tegeder, Q Tan, AK Grennan, JW Patrick Functional Plant Biology 34 (11), 1019-1028, 2007 | 45 | 2007 |
Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS CS Kao, R van Bruggen, JR Kim, XXL Chen, C Chan, J Lee, WI Cho, ... Nature communications 11 (1), 5304, 2020 | 40 | 2020 |
Function of pea amino acid permease AAP6 in nodule nitrogen metabolism and export, and plant nutrition MG Garneau, Q Tan, M Tegeder Journal of experimental botany 69 (21), 5205-5219, 2018 | 37 | 2018 |
PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1 VV Bondar, CJ Adamski, TS Onur, Q Tan, L Wang, J Diaz-Garcia, J Park, ... Human molecular genetics 27 (16), 2863-2873, 2018 | 25 | 2018 |
Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis A Didonna, E Canto Puig, Q Ma, A Matsunaga, B Ho, SJ Caillier, H Shams, ... Proceedings of the National Academy of Sciences 117 (38), 23742-23750, 2020 | 22 | 2020 |
Mouse models as a tool for discovering new neurological diseases Q Tan, HY Zoghbi Neurobiology of Learning and Memory 165, 106902, 2019 | 19 | 2019 |
Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis H Hong, J Lee, GY Park, S Kim, J Park, JS Park, Y Song, S Lee, TJ Kim, ... Cell Reports 38 (7), 2022 | 8 | 2022 |
Capicua regulates the development of adult-born neurons in the hippocampus B Hourigan, SD Balay, G Yee, S Sharma, Q Tan Scientific Reports 11 (1), 11725, 2021 | 8 | 2021 |
Alzheimer’s disease associated isoforms of human CD33 distinctively modulate microglial cell responses in 5XFAD mice G Eskandari-Sedighi, M Crichton, S Zia, E Gomez-Cardona, LM Cortez, ... Molecular Neurodegeneration 19 (1), 42, 2024 | 5 | 2024 |
Novel CIC variants identified in individuals with neurodevelopmental phenotypes S Sharma, B Hourigan, Z Patel, JA Rosenfeld, KM Chan, MF Wangler, ... Human Mutation 43 (7), 889-899, 2022 | 5 | 2022 |
MATR3 pathogenic variants differentially impair its cryptic splicing repression function M Khan, XXL Chen, M Dias, JR Santos, S Kour, J You, R van Bruggen, ... FEBS letters 598 (4), 415-436, 2024 | 4 | 2024 |