| SOX10 single transcription factor-based fast and efficient generation of oligodendrocytes from human pluripotent stem cells JA García-León, M Kumar, R Boon, D Chau, J One, E Wolfs, K Eggermont, ... Stem cell reports 10 (2), 655-672, 2018 | 107 | 2018 |
| Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer’s disease-like pathology D Baglietto-Vargas, S Forner, L Cai, AC Martini, L Trujillo-Estrada, ... Nature communications 12 (1), 2421, 2021 | 82 | 2021 |
| Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis A Alcina, M Fedetz, Ó Fernández, A Saiz, G Izquierdo, M Lucas, L Leyva, ... Journal of medical genetics 50 (1), 25-33, 2013 | 74 | 2013 |
| Transgenic mouse models of Alzheimer’s disease: An integrative analysis R Sanchez-Varo, M Mejias-Ortega, JJ Fernandez-Valenzuela, ... International Journal of Molecular Sciences 23 (10), 5404, 2022 | 72 | 2022 |
| Distinct disease‐sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients E Sanchez‐Mejias, C Nuñez‐Diaz, R Sanchez‐Varo, ... Brain Pathology 30 (2), 345-363, 2020 | 62 | 2020 |
| Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule‐associated protein TAU mutations which displays several phenotypes … JA García‐León, A Cabrera‐Socorro, K Eggermont, A Swijsen, J Terryn, ... Alzheimer's & Dementia 14 (10), 1261-1280, 2018 | 51 | 2018 |
| Killer cell immunoglobulin-like receptor genes in Spanish multiple sclerosis patients JA García-León, MJ Pinto-Medel, L García-Trujillo, C López-Gómez, ... Molecular immunology 48 (15-16), 1896-1902, 2011 | 51 | 2011 |
| Kinetics and incidence of anti-natalizumab antibodies in multiple sclerosis patients on treatment for 18 months B Oliver, Ó Fernández, T Órpez, MP Alvarenga, MJ Pinto-Medel, ... Multiple Sclerosis Journal 17 (3), 368-371, 2011 | 49 | 2011 |
| The CD4+ T-cell subset lacking expression of the CD28 costimulatory molecule is expanded and shows a higher activation state in multiple sclerosis MJ Pinto-Medel, JA García-León, B Oliver-Martos, C López-Gómez, ... Journal of Neuroimmunology 243 (1-2), 1-11, 2012 | 36 | 2012 |
| Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells JA García-León, B García-Díaz, K Eggermont, L Cáceres-Palomo, ... Nature Protocols 15 (11), 3716-3744, 2020 | 34 | 2020 |
| Human pluripotent stem cell-derived neural cells as a relevant platform for drug screening in Alzheimer’s disease JA Garcia-Leon, L Caceres-Palomo, E Sanchez-Mejias, M Mejias-Ortega, ... International Journal of Molecular Sciences 21 (18), 6867, 2020 | 28 | 2020 |
| Use of human pluripotent stem cell-derived cells for neurodegenerative disease modeling and drug screening platform JA Garcia-Leon, J Vitorica, A Gutierrez Future medicinal chemistry 11 (11), 1305-1322, 2019 | 27 | 2019 |
| TRAIL/TRAIL receptor system and susceptibility to multiple sclerosis C Lopez-Gomez, O Fernandez, JA García-León, MJ Pinto-Medel, ... PLoS One 6 (7), e21766, 2011 | 24 | 2011 |
| Gene expression in IFNss signalling pathway differs between monocytes, CD4 and CD8 T cells from MS patients B Oliver-Martos, T Orpez, MJ Pinto-Medel, C Mayorga, JA Garcia-Leon, ... Journal of neuroimmunology 230 (1-2), 153-159, 2011 | 20 | 2011 |
| Animal and cellular models of Alzheimer’s disease: Progress, promise, and future approaches L Trujillo-Estrada, E Sanchez-Mejias, R Sanchez-Varo, JA Garcia-Leon, ... The Neuroscientist 28 (6), 572-593, 2022 | 17 | 2022 |
| Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer’s disease hippocampus C Muñoz-Castro, M Mejias-Ortega, E Sanchez-Mejias, V Navarro, ... Acta neuropathologica communications 11 (1), 31, 2023 | 14 | 2023 |
| Single transcription factor-based differentiation allowing fast and efficient oligodendrocyte generation via SOX10 overexpression K Neyrinck, JA García-León Neural Reprogramming: Methods and Protocols, 149-170, 2021 | 7 | 2021 |
| Genetically Engineered Triple MAPT-Mutant Human-Induced Pluripotent Stem Cells (N279K, P301L, and E10+16 Mutations) Exhibit Impairments in Mitochondrial … L Szabo, A Grimm, JA García-León, CM Verfaillie, A Eckert Cells 12 (10), 1385, 2023 | 4 | 2023 |
| Stem Cell-Derived Oligodendroglial Cells for Therapy in Neurological Diseases VCM García-León JA Curr Stem Cell Res Ther. 11 (7), 569-77, 2016 | 4 | 2016 |
| Killer-cell immunoglobulin-like receptor expression on lymphocyte subsets in multiple sclerosis patients treated with interferon-β: evaluation as biomarkers for clinical response JA García-León, C López-Gómez, T Orpez-Zafra, V Reyes-Garrido, ... CNS drugs 28, 559-570, 2014 | 2 | 2014 |
