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Ulla Gerling-Driessen
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Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions
M Salwiczek, EK Nyakatura, UIM Gerling, S Ye, B Koksch
Chemical Society Reviews 41 (6), 2135-2171, 2012
4712012
Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity
FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ...
ACS central science 3 (11), 1143-1155, 2017
1892017
Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers
PD Rakowska, H Jiang, S Ray, A Pyne, B Lamarre, M Carr, PJ Judge, ...
Proceedings of the National Academy of Sciences 110 (22), 8918-8923, 2013
1512013
Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity
UIM Gerling, M Salwiczek, CD Cadicamo, H Erdbrink, C Czekelius, ...
Chemical Science 5 (2), 819-830, 2014
832014
Conjugate hydrotrifluoromethylation of α, β-unsaturated acyl-oxazolidinones: synthesis of chiral fluorinated amino acids
H Erdbrink, I Peuser, UIM Gerling, D Lentz, B Koksch, C Czekelius
Organic & Biomolecular Chemistry 10 (43), 8583-8586, 2012
652012
The amyloid precursor protein C-terminal fragment C100 occurs in monomeric and dimeric stable conformations and binds γ-secretase modulators
A Botev, LM Munter, R Wenzel, L Richter, V Althoff, J Ismer, U Gerling, ...
Biochemistry 50 (5), 828-835, 2011
372011
Discovery and investigation of natural editing function against artificial amino acids in protein translation
JS Völler, M Dulic, UIM Gerling-Driessen, H Biava, T Baumann, ...
ACS central science 3 (1), 73-80, 2017
272017
Structure analysis of an amyloid-forming model peptide by a systematic glycine and proline scan
UIM Gerling, E Brandenburg, H Berlepsch, K Pagel, B Koksch
Biomacromolecules 12 (8), 2988-2996, 2011
272011
Synthesis of enantiomerically pure (2S, 3S)-5, 5, 5-trifluoroisoleucine and (2R, 3S)-5, 5, 5-trifluoro-allo-isoleucine
H Erdbrink, EK Nyakatura, S Huhmann, UIM Gerling, D Lentz, B Koksch, ...
Beilstein Journal of Organic Chemistry 9 (1), 2009-2014, 2013
252013
Effects of single substitutions with hexafluoroleucine and trifluorovaline on the hydrophobic core formation of a heterodimeric coiled coil
S Huhmann, EK Nyakatura, H Erdbrink, UIM Gerling, C Czekelius, ...
Journal of Fluorine Chemistry 175, 32-35, 2015
242015
Inhibition of amyloid aggregation by formation of helical assemblies
E Brandenburg, H von Berlepsch, UIM Gerling, C Böttcher, B Koksch
Chemistry–A European Journal 17 (38), 10651-10661, 2011
242011
Glycopolymers against pathogen infection
UIM Gerling-Driessen, M Hoffmann, S Schmidt, NL Snyder, L Hartmann
Chemical Society Reviews 52 (8), 2617-2642, 2023
212023
Multiple glycosylation of de novo designed α-helical coiled coil peptides
JA Falenski, UIM Gerling, B Koksch
Bioorganic & medicinal chemistry 18 (11), 3703-3706, 2010
192010
Exploiting Oligo (amido amine) backbones for the multivalent presentation of coiled-coil peptides
UIM Gerling-Driessen, N Mujkic-Ninnemann, D Ponader, D Schöne, ...
Biomacromolecules 16 (8), 2394-2402, 2015
172015
Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity. ACS Cent Sci 3: 1143–1155
FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ...
PLoS Genet 13, e1006696, 2017
102017
Thiourea derivatives as chelating agents for bioconjugation of rhenium and technetium
JDC Gomez, A Hagenbach, UIM Gerling-Driessen, B Koksch, N Beindorff, ...
Dalton Transactions 46 (42), 14602-14611, 2017
102017
The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide
MS de Freitas, RR Araghi, E Brandenburg, J Leiterer, F Emmerling, ...
Journal of Structural Biology 203 (3), 263-272, 2018
52018
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity. ACS Central Science, 3 (11), 1143–1155
FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ...
52017
Proline-glutamate chimera’s side chain conformation directs the type of β-hairpin structure
J Maity, UIM Gerling, S Vukelić, A Schäfer, B Koksch
Amino acids 46, 177-186, 2014
42014
An approach for simultaneous synthesis of cis-and trans-3-substituted proline-glutamic acid chimeras
J Maity, P Saha, UIM Gerling, D Lentz, B Koksch
Synthesis 44 (19), 3063-3070, 2012
42012
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