The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase L Afriat, C Roodveldt, G Manco, DS Tawfik Biochemistry 45 (46), 13677-13686, 2006 | 299 | 2006 |
Structural basis for natural lactonase and promiscuous phosphotriesterase activities M Elias, J Dupuy, L Merone, L Mandrich, E Porzio, S Moniot, D Rochu, ... Journal of molecular biology 379 (5), 1017-1028, 2008 | 196 | 2008 |
Overexpression and properties of a new thermophilic and thermostable esterase from Bacillus acidocaldarius with sequence similarity to hormone-sensitive lipase subfamily G MANCO, E Adinolfi, FM PISANI, G OTTOLINA, G CARREA, M ROSSI Biochemical Journal 332 (1), 203-212, 1998 | 181 | 1998 |
The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus G De Simone, V Menchise, G Manco, L Mandrich, N Sorrentino, D Lang, ... Journal of Molecular Biology 314 (3), 507-518, 2001 | 179 | 2001 |
A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase G De Simone, S Galdiero, G Manco, D Lang, M Rossi, C Pedone Journal of Molecular Biology 303 (5), 761-771, 2000 | 165 | 2000 |
Cloning, overexpression, and properties of a new thermophilic and thermostable esterase with sequence similarity to hormone-sensitive lipase subfamily from the archaeon … G Manco, E Giosuè, S D'Auria, P Herman, G Carrea, M Rossi Archives of Biochemistry and Biophysics 373 (1), 182-192, 2000 | 165 | 2000 |
A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: cloning, overexpression and properties L Merone, L Mandrich, M Rossi, G Manco Extremophiles 9, 297-305, 2005 | 157 | 2005 |
Role of the N terminus in enzyme activity, stability and specificity in thermophilic esterases belonging to the HSL family L Mandrich, L Merone, M Pezzullo, L Cipolla, F Nicotra, M Rossi, G Manco Journal of Molecular Biology 345 (3), 501-512, 2005 | 95 | 2005 |
A novel aspartyl proteinase from apocrine epithelia and breast tumors E Caputo, G Manco, L Mandrich, J Guardiola Journal of Biological Chemistry 275 (11), 7935-7941, 2000 | 91 | 2000 |
Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure R Ferriero, E Nusco, R De Cegli, A Carissimo, G Manco, N Brunetti-Pierri Journal of Hepatology 69 (2), 325-335, 2018 | 88 | 2018 |
A new phosphotriesterase from Sulfolobus acidocaldarius and its comparison with the homologue from Sulfolobus solfataricus E Porzio, L Merone, L Mandrich, M Rossi, G Manco Biochimie 89 (5), 625-636, 2007 | 79 | 2007 |
Cell surface display of organophosphorus hydrolase for sensitive spectrophotometric detection of p-nitrophenol substituted organophosphates X Tang, B Liang, T Yi, G Manco, A Liu Enzyme and microbial technology 55, 107-112, 2014 | 78 | 2014 |
Denaturing action of urea and guanidine hydrochloride towards two thermophilic esterases PDEL VECCHIO, G Graziano, V Granata, G Barone, L Mandrich, M Rossi, ... Biochemical Journal 367 (3), 857-863, 2002 | 77 | 2002 |
Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases H Chahinian, YB Ali, A Abousalham, S Petry, L Mandrich, G Manco, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2005 | 76 | 2005 |
Stability and activity of a thermostable malic enzyme in denaturants and water‐miscible organic solvents A Guagliardi, G Manco, S BARTOLUCCI European journal of biochemistry 183 (1), 25-30, 1989 | 74 | 1989 |
Structure-function analysis of the EGF-CFC family member Cripto identifies residues essential for nodal signalling G Minchiotti, G Manco, S Parisi, CT Lago, F Rosa, MG Persico Oxford University Press for The Company of Biologists Limited 128 (22), 4501 …, 2001 | 72 | 2001 |
Phenylbutyrate therapy for pyruvate dehydrogenase complex deficiency and lactic acidosis. BPN Ferriero R, Manco G, Lamantea E, Nusco E, Ferrante MI, Sordino P ... Sci Transl Med., 2013 | 70 | 2013 |
Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus P Del Vecchio, M Elias, L Merone, G Graziano, J Dupuy, L Mandrich, ... Extremophiles 13, 461-470, 2009 | 68 | 2009 |
Human paraoxonase-2 (PON2): protein functions and modulation G Manco, E Porzio, TM Carusone Antioxidants 10 (2), 256, 2021 | 66 | 2021 |
Enzymatic detoxification: a sustainable means of degrading toxic organophosphate pesticides and chemical warfare nerve agents G Manco, E Porzio, Y Suzumoto Journal of Chemical Technology & Biotechnology 93 (8), 2064-2082, 2018 | 64 | 2018 |