Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding J Schlöndorff, CP Blobel Journal of cell science 112 (21), 3603-3617, 1999 | 714 | 1999 |
Evidence for a role of a tumor necrosis factor-α (TNF-α)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic … L Lum, BR Wong, R Josien, JD Becherer, H Erdjument-Bromage, ... Journal of Biological Chemistry 274 (19), 13613-13618, 1999 | 586 | 1999 |
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis EJ Brown, JS Schlöndorff, DJ Becker, H Tsukaguchi, SJ Tonna, ... Nature genetics 42 (1), 72-76, 2010 | 511 | 2010 |
Intracellular maturation and localization of the tumour necrosis factor α convertase (TACE) J Schlöndorff, JD Becherer, CP Blobel Biochemical Journal 347 (1), 131-138, 2000 | 491 | 2000 |
Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels D Tian, SMP Jacobo, D Billing, A Rozkalne, SD Gage, T Anagnostou, ... Science signaling 3 (145), ra77-ra77, 2010 | 307 | 2010 |
TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription J Schlöndorff, D Del Camino, R Carrasquillo, V Lacey, MR Pollak American Journal of Physiology-Cell Physiology 296 (3), C558-C569, 2009 | 208 | 2009 |
Evidence for a critical role of the tumor necrosis factor α convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR) G Weskamp, J Schlöndorff, L Lum, JD Becherer, TW Kim, P Saftig, ... Journal of Biological Chemistry 279 (6), 4241-4249, 2004 | 204 | 2004 |
APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases OA Olabisi, JY Zhang, L VerPlank, N Zahler, S DiBartolo III, JF Heneghan, ... Proceedings of the National Academy of Sciences 113 (4), 830-837, 2016 | 199 | 2016 |
Disease-associated mutant α-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity A Weins, JS Schlondorff, F Nakamura, BM Denker, JH Hartwig, TP Stossel, ... Proceedings of the National Academy of Sciences 104 (41), 16080-16085, 2007 | 187 | 2007 |
Evidence for regulation of the tumor necrosis factor α-convertase (TACE) by protein-tyrosine phosphatase PTPH1 Y Zheng, J Schlöndorff, CP Blobel Journal of Biological Chemistry 277 (45), 42463-42470, 2002 | 176 | 2002 |
Six members of the mouse forkhead gene family are developmentally regulated. KH Kaestner, KH Lee, J Schlöndorff, H Hiemisch, AP Monaghan, ... Proceedings of the National Academy of Sciences 90 (16), 7628-7631, 1993 | 171 | 1993 |
Biochemical and pharmacological criteria define two shedding activities for TRANCE/OPGL that are distinct from the tumor necrosis factor α convertase J Schlöndorff, L Lum, CP Blobel Journal of Biological Chemistry 276 (18), 14665-14674, 2001 | 160 | 2001 |
Small molecule targets TMED9 and promotes lysosomal degradation to reverse proteinopathy M Dvela-Levitt, M Kost-Alimova, M Emani, E Kohnert, R Thompson, ... Cell 178 (3), 521-535. e23, 2019 | 153 | 2019 |
Evidence for an interaction of the metalloprotease–disintegrin tumour necrosis factor α convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease … KK Nelson, J Schlöndorff, CP Blobel Biochemical Journal 343 (3), 673-680, 1999 | 133 | 1999 |
Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development KH Kaestner, SC Bleckmann, AP Monaghan, J Schlöndorff, A Mincheva, ... Development 122 (6), 1751-1758, 1996 | 111 | 1996 |
Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2) H Sun, JS Schlondorff, EJ Brown, HN Higgs, MR Pollak Proceedings of the National Academy of Sciences 108 (7), 2933-2938, 2011 | 85 | 2011 |
Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling H Sun, J Schlondorff, HN Higgs, MR Pollak Journal of the American Society of Nephrology 24 (6), 917-929, 2013 | 71 | 2013 |
Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2) D Chiluiza, S Krishna, VA Schumacher, J Schlöndorff Journal of Biological Chemistry 288 (25), 18407-18420, 2013 | 70 | 2013 |
Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis M Barua, E Shieh, J Schlondorff, G Genovese, BS Kaplan, MR Pollak Kidney international 85 (1), 124-133, 2014 | 51 | 2014 |
Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury B Subramanian, H Sun, P Yan, VT Charoonratana, HN Higgs, F Wang, ... Kidney international 90 (2), 363-372, 2016 | 47 | 2016 |