Modulation of activity profiles for largazole-based HDAC inhibitors through alteration of prodrug properties LA Salvador, H Park, FH Al-Awadhi, Y Liu, B Kim, SL Zeller, QY Chen, ... ACS Medicinal Chemistry Letters 5 (8), 905-910, 2014 | 48 | 2014 |
Grassystatins D–F, potent aspartic protease inhibitors from marine Cyanobacteria as potential antimetastatic agents targeting invasive breast cancer FH Al-Awadhi, BK Law, VJ Paul, H Luesch Journal of natural products 80 (11), 2969-2986, 2017 | 43 | 2017 |
Kempopeptin C, a novel marine-derived serine protease inhibitor targeting invasive breast cancer FH Al-Awadhi, LA Salvador, BK Law, VJ Paul, H Luesch Marine drugs 15 (9), 290, 2017 | 39 | 2017 |
Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium FH Al-Awadhi, R Ratnayake, VJ Paul, H Luesch Bioorganic & medicinal chemistry 24 (15), 3276-3282, 2016 | 38 | 2016 |
Structural diversity and anticancer activity of marine‐derived elastase inhibitors: key features and mechanisms mediating the antimetastatic effects in invasive breast cancer FH Al‐Awadhi, VJ Paul, H Luesch ChemBioChem 19 (8), 815-825, 2018 | 31 | 2018 |
Targeting eukaryotic proteases for natural products-based drug development FH Al-Awadhi, H Luesch Natural Product Reports 37 (6), 827-860, 2020 | 25 | 2020 |
Largazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases FH Al-Awadhi, LA Salvador-Reyes, LA Elsadek, R Ratnayake, QY Chen, ... ACS Chemical Neuroscience 11 (13), 1937-1943, 2020 | 23 | 2020 |
Discovery, synthesis, pharmacological profiling, and biological characterization of brintonamides A–E, novel dual protease and GPCR modulators from a marine cyanobacterium FH Al-Awadhi, B Gao, MA Rezaei, JC Kwan, C Li, T Ye, VJ Paul, ... Journal of medicinal chemistry 61 (14), 6364-6378, 2018 | 23 | 2018 |
Flash vacuum pyrolysis of acetylenic esters: A mechanistic study NA Al-Awadi, AS Mohamed, OM Habib, FH Al-Awadhi, NA Al-Jalal, ... Journal of Analytical and Applied Pyrolysis 146, 104778, 2020 | 9 | 2020 |
Flash vacuum pyrolysis of acetylenic amides: A mechanistic study YAI Nouria A Al-Awadi, Asaad S Mohamed, Osama M Habib, Fatma H Al-Awadhi ... Journal of Analytical and Applied Pyrolysis 150, 104894, 2020 | 8 | 2020 |
Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway FH Al-Awadhi, EF Simon, N Liu, R Ratnayake, VJ Paul, H Luesch Marine Drugs 21 (11), 553, 2023 | 3 | 2023 |
Anti-progressive effects of a series of glycinyl and alaninyl triazolyl-oxazolidinones on Kelly neuroblastoma cell line NA Al-Hasawi, OA Phillips, F Al-Awadhi, LH Sharaf, SA Amine, L Novotny Anticancer Research 40 (9), 5125-5140, 2020 | 3 | 2020 |
7 ChAPtEr Screening Strategies for Drug Discovery and target Identification FH Al-Awadhi, LA Salvador, H Luesch Marine Biomedicine: From Beach to Bedside, 135, 2015 | 3 | 2015 |
Variable-Sized bis (4-spiro-fused-β-lactam)-Based Unsaturated Macrocycles: Synthesis and Characterization AS Mohamed, FH Al-Awadhi, NA Al-Awadi ACS omega 7 (41), 36795-36803, 2022 | 2 | 2022 |
Gas-phase pyrolysis of benzo-and naphthofuran derivatives YA Ibrahim, AS Mohamed, OM Habib, FH Al-Awadhi, NA Al-Jalal, ... Journal of Analytical and Applied Pyrolysis 142, 104626, 2019 | 1 | 2019 |
Empowering competence: A program-wide active learning framework for a pharmacy program D Al-Taweel, P Moreau, S Koshy, MA Khedr, N Nafee, A Al-Romaiyan, ... American Journal of Pharmaceutical Education 88 (10), 101272, 2024 | | 2024 |
Isolation and Characterization of the Cyanobacterial Macrolide Glycoside Moorenaside, an Anti-Inflammatory Analogue of Aurisides Targeting the Keap1/Nrf2 Pathway FH Al-Awadhi, S Kokkaliari, R Ratnayake, VJ Paul, H Luesch Journal of Natural Products 87 (10), 2355-2365, 2024 | | 2024 |
Cover Feature: Structural Diversity and Anticancer Activity of Marine‐Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive … FH Al‐Awadhi, VJ Paul, H Luesch ChemBioChem 19 (8), 765-765, 2018 | | 2018 |
Isolation, structure elucidation and biological evaluation of novel cathepsin inhibitors from marine cyanobacteria FH Al-Awadhi, V Paul, H Luesch Planta Medica 81 (11), PQ18, 2015 | | 2015 |