Endothelial activation and blood–brain barrier disruption in neurotoxicity after adoptive immunotherapy with CD19 CAR-T cells J Gust, KA Hay, LA Hanafi, D Li, D Myerson, LF Gonzalez-Cuyar, C Yeung, ... Cancer discovery 7 (12), 1404-1419, 2017 | 1247 | 2017 |
Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy KA Hay, LA Hanafi, D Li, J Gust, WC Liles, MM Wurfel, JA López, J Chen, ... Blood, The Journal of the American Society of Hematology 130 (21), 2295-2306, 2017 | 1024 | 2017 |
In vitro microvessels for the study of angiogenesis and thrombosis Y Zheng, J Chen, M Craven, NW Choi, S Totorica, A Diaz-Santana, ... Proceedings of the national academy of sciences 109 (24), 9342-9347, 2012 | 1019 | 2012 |
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice J Chen, A Reheman, FC Gushiken, L Nolasco, X Fu, JL Moake, H Ni, ... The Journal of clinical investigation 121 (2), 593-603, 2011 | 269 | 2011 |
Inflammation, von Willebrand factor, and ADAMTS13 J Chen, DW Chung Blood, The Journal of the American Society of Hematology 132 (2), 141-147, 2018 | 231 | 2018 |
Interactions of platelets with subendothelium and endothelium J Chen, JA López Microcirculation 12 (3), 235-246, 2005 | 228 | 2005 |
Formation of microvascular networks in vitro JP Morgan, PF Delnero, Y Zheng, SS Verbridge, J Chen, M Craven, ... Nature protocols 8 (9), 1820-1836, 2013 | 219 | 2013 |
Pathophysiology of venous thrombosis JA López, J Chen Thrombosis research 123, S30-S34, 2009 | 219 | 2009 |
Flow-driven assembly of VWF fibres and webs in in vitro microvessels Y Zheng, J Chen, JA López Nature communications 6 (1), 7858, 2015 | 163 | 2015 |
Increasing the thermostability of staphylococcal nuclease: implications for the origin of protein thermostability J Chen, Z Lu, J Sakon, WE Stites Journal of molecular biology 303 (2), 125-130, 2000 | 160 | 2000 |
Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13 J Chen, X Fu, Y Wang, M Ling, B McMullen, J Kulman, DW Chung, ... Blood, The Journal of the American Society of Hematology 115 (3), 706-712, 2010 | 159 | 2010 |
Packing is a key selection factor in the evolution of protein hydrophobic cores J Chen, WE Stites Biochemistry 40 (50), 15280-15289, 2001 | 118 | 2001 |
The rate of hemolysis in sickle cell disease correlates with the quantity of active von Willebrand factor in the plasma J Chen, WE Hobbs, J Le, PJ Lenting, PG de Groot, JA López Blood, The Journal of the American Society of Hematology 117 (13), 3680-3683, 2011 | 112 | 2011 |
The platelet glycoprotein Ib–von Willebrand factor interaction activates the collagen receptor α2β1 to bind collagen: activation-dependent conformational change of the α2-I domain MA Cruz, J Chen, JL Whitelock, LD Morales, JA López Blood 105 (5), 1986-1991, 2005 | 97 | 2005 |
High-density lipoprotein modulates thrombosis by preventing von Willebrand factor self-association and subsequent platelet adhesion DW Chung, J Chen, M Ling, X Fu, T Blevins, S Parsons, J Le, J Harris, ... Blood, The Journal of the American Society of Hematology 127 (5), 637-645, 2016 | 96 | 2016 |
Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib Y Latifi, F Moccetti, M Wu, A Xie, W Packwood, Y Qi, K Ozawa, W Shentu, ... Blood, The Journal of the American Society of Hematology 133 (14), 1597-1606, 2019 | 84 | 2019 |
Shear stress–induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region X Fu, J Chen, R Gallagher, Y Zheng, DW Chung, JA López Blood, The Journal of the American Society of Hematology 118 (19), 5283-5291, 2011 | 80 | 2011 |
miR-155 modifies inflammation, endothelial activation and blood-brain barrier dysfunction in cerebral malaria KR Barker, Z Lu, H Kim, Y Zheng, J Chen, AL Conroy, M Hawkes, ... Molecular medicine 23, 24-33, 2017 | 74 | 2017 |
Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation I Johnston, A Sarkar, V Hayes, GT Koma, GM Arepally, J Chen, ... Blood, The Journal of the American Society of Hematology 135 (15), 1270-1280, 2020 | 65 | 2020 |
Hypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation Y Wang, J Chen, M Ling, JA López, DW Chung, X Fu Journal of Biological Chemistry 290 (3), 1422-1431, 2015 | 63 | 2015 |