NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma CL Wilson, D Jurk, N Fullard, P Banks, A Page, S Luli, AM Elsharkawy, ... Nature communications 6 (1), 6818, 2015 | 181 | 2015 |
CXCR2 inhibition enables NASH-HCC immunotherapy J Leslie, JBG Mackey, T Jamieson, E Ramon-Gil, TM Drake, F Fercoq, ... Gut 71 (10), 2093-2106, 2022 | 92 | 2022 |
A proof-of-concept for epigenetic therapy of tissue fibrosis: inhibition of liver fibrosis progression by 3-deazaneplanocin A M Zeybel, S Luli, L Sabater, T Hardy, F Oakley, J Leslie, A Page, ... Molecular Therapy 25 (1), 218-231, 2017 | 77 | 2017 |
Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease C Fox, P Cocchiaro, F Oakley, R Howarth, K Callaghan, J Leslie, S Luli, ... Scientific Reports 6 (1), 20101, 2016 | 71 | 2016 |
FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis J Leslie, BJM Millar, A del Carpio Pons, RA Burgoyne, JD Frost, ... JCI insight 5 (4), 2020 | 64 | 2020 |
Loss of endothelial endoglin promotes high-output heart failure through peripheral arteriovenous shunting driven by VEGF signaling S Tual-Chalot, M Garcia-Collado, RE Redgrave, E Singh, B Davison, ... Circulation Research 126 (2), 243-257, 2020 | 51 | 2020 |
Inhibition of RelA‐Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response A Moles, AM Sanchez, PS Banks, LB Murphy, S Luli, L Borthwick, A Fisher, ... Hepatology 57 (2), 817-828, 2013 | 45 | 2013 |
Fibrogenic activity of MECP2 is regulated by phosphorylation in hepatic stellate cells E Moran-Salvador, M Garcia-Macia, A Sivaharan, L Sabater, MYW Zaki, ... Gastroenterology 157 (5), 1398-1412. e9, 2019 | 31 | 2019 |
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis J Leslie, MG Macia, S Luli, JC Worrell, WJ Reilly, HL Paish, A Knox, ... Nature metabolism 2 (11), 1350-1367, 2020 | 29 | 2020 |
A new fluorescence-based optical imaging method to non-invasively monitor hepatic myofibroblasts in vivo S Luli, D Di Paolo, P Perri, C Brignole, SJ Hill, H Brown, J Leslie, ... Journal of hepatology 65 (1), 75-83, 2016 | 19 | 2016 |
Synthesis and In Vivo Evaluation of a Site-specifically Labeled Radioimmunoconjugate for Dual-Modal (PET/NIRF) Imaging of MT1-MMP in Sarcomas TA Pringle, CD Chan, S Luli, HJ Blair, KS Rankin, JC Knight Bioconjugate chemistry 33 (8), 1564-1573, 2022 | 13 | 2022 |
Anti–Cholestatic Therapy with obeticholic acid improves short-term memory in bile duct–ligated mice LMV Gee, B Barron-Millar, J Leslie, C Richardson, MYW Zaki, S Luli, ... The American Journal of Pathology 193 (1), 11-26, 2023 | 9 | 2023 |
Mutation of the RelA (p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance JE Hunter, AE Campbell, JA Butterworth, H Sellier, NL Hannaway, S Luli, ... Biochemical Journal 479 (19), 2087-2113, 2022 | 9 | 2022 |
Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice O Kamala, TH Malik, TM Hallam, TE Cox, Y Yang, F Vyas, S Luli, ... Frontiers in Immunology 12, 752916, 2021 | 9 | 2021 |
Non-invasive synchronous monitoring of neutrophil migration using whole body near-infrared fluorescence-based imaging J Leslie, SM Robinson, F Oakley, S Luli Scientific Reports 11 (1), 1415, 2021 | 9 | 2021 |
Enhanced in vivo Optical Imaging of the Inflammatory Response to Acute Liver Injury in C57BL/6 Mice Using a Highly Bright Near‐Infrared BODIPY Dye D Sirbu, S Luli, J Leslie, F Oakley, AC Benniston ChemMedChem 14 (10), 995-999, 2019 | 9 | 2019 |
Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway JE Hunter, AE Campbell, NL Hannaway, S Kerridge, S Luli, ... Biochemical Journal 479 (19), 2063-2086, 2022 | 8 | 2022 |
Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells JE Hunter, AE Campbell, S Kerridge, C Fraser, NL Hannaway, S Luli, ... Biochemical Journal 479 (19), 2131-2151, 2022 | 6 | 2022 |
Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation B Zadran, PD Sudhindar, D Wainwright, Y Bury, S Luli, R Howarth, ... British Journal of Cancer 128 (7), 1236-1248, 2023 | 4 | 2023 |
Regulation of checkpoint kinase signalling and tumorigenesis by the NF-κB regulated gene, CLSPN JE Hunter, JA Butterworth, H Sellier, S Luli, A Floudas, AJ Moore, ... BioRxiv, 358291, 2018 | 4 | 2018 |