Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells M Karow, R Sánchez, C Schichor, G Masserdotti, F Ortega, C Heinrich, ... Cell stem cell 11 (4), 471-476, 2012 | 358 | 2012 |
Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming S Gascón, E Murenu, G Masserdotti, F Ortega, GL Russo, D Petrik, ... Cell stem cell 18 (3), 396-409, 2016 | 348 | 2016 |
Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signalling F Ortega, S Gascón, G Masserdotti, A Deshpande, C Simon, J Fischer, ... Nature cell biology 15 (6), 602-613, 2013 | 250 | 2013 |
Continuous live imaging of adult neural stem cell division and lineage progression in vitro MR Costa, F Ortega, MS Brill, R Beckervordersandforth, C Petrone, ... Development 138 (6), 1057-1068, 2011 | 192 | 2011 |
Bifunctional hydrogels containing the laminin motif IKVAV promote neurogenesis A Farrukh, F Ortega, W Fan, N Marichal, JI Paez, B Berninger, ... Stem cell reports 9 (5), 1432-1440, 2017 | 111 | 2017 |
P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons F Ortega, R Pérez-Sen, V Morente, EG Delicado, MT Miras-Portugal Cellular and molecular life sciences 67, 1723-1733, 2010 | 100 | 2010 |
The purinergic P2Y13 receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death S Espada, F Ortega, E Molina-Jijón, AI Rojo, R Pérez-Sen, ... Free Radical Biology and Medicine 49 (3), 416-426, 2010 | 99 | 2010 |
ERK1/2 activation is involved in the neuroprotective action of P2Y13 and P2X7 receptors against glutamate excitotoxicity in cerebellar granule neurons F Ortega, R Pérez-Sen, EG Delicado, MT Miras-Portugal Neuropharmacology 61 (8), 1210-1221, 2011 | 82 | 2011 |
Nucleotides in neuroregeneration and neuroprotection MT Miras-Portugal, R Gomez-Villafuertes, J Gualix, JI Diaz-Hernandez, ... Neuropharmacology 104, 243-254, 2016 | 75 | 2016 |
P2X7 Nucleotide Receptor is Coupled to GSK-3 Inhibition and Neuroprotection in Cerebellar Granule Neurons F Ortega, R Pérez-Sen, EG Delicado, MT Miras-Portugal Neurotoxicity research 15, 193-204, 2009 | 75 | 2009 |
Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level F Ortega, MR Costa, T Simon-Ebert, T Schroeder, M Götz, B Berninger nature protocols 6 (12), 1847-1859, 2011 | 58 | 2011 |
Dual-specificity phosphatase regulation in neurons and glial cells R Pérez-Sen, MJ Queipo, JC Gil-Redondo, F Ortega, ... International Journal of Molecular Sciences 20 (8), 1999, 2019 | 56 | 2019 |
Gi‐coupled P2Y‐ADP receptor mediates GSK‐3 phosphorylation and β‐catenin nuclear translocation in granule neurons F Ortega, R Pérez‐Sen, MT Miras‐Portugal Journal of neurochemistry 104 (1), 62-73, 2008 | 47 | 2008 |
CEND1 and NEUROGENIN2 reprogram mouse astrocytes and embryonic fibroblasts to induced neural precursors and differentiated neurons K Aravantinou-Fatorou, F Ortega, D Chroni-Tzartou, N Antoniou, ... Stem cell reports 5 (3), 405-418, 2015 | 43 | 2015 |
P2 receptor interaction and signalling cascades in neuroprotection MT Miras-Portugal, MJ Queipo, JC Gil-Redondo, F Ortega, ... Brain Research Bulletin 151, 74-83, 2019 | 42 | 2019 |
Neuroprotection elicited by P2Y13 receptors against genotoxic stress by inducing DUSP2 expression and MAPK signaling recovery V Morente, R Pérez-Sen, F Ortega, J Huerta-Cepas, EG Delicado, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (9), 1886-1898, 2014 | 42 | 2014 |
Neuroprotection mediated by P2Y13 nucleotide receptors in neurons R Pérez-Sen, MJ Queipo, V Morente, F Ortega, EG Delicado, ... Computational and structural biotechnology journal 13, 160-168, 2015 | 41 | 2015 |
Conversion of nonproliferating astrocytes into neurogenic neural stem cells: control by FGF2 and interferon-γ S Kleiderman, S Gutbier, K Ugur Tufekci, F Ortega, JV Sá, AP Teixeira, ... Stem Cells 34 (12), 2861-2874, 2016 | 40 | 2016 |
JNK‐dependent gene regulatory circuitry governs mesenchymal fate SK Sahu, A Garding, N Tiwari, S Thakurela, J Toedling, S Gebhard, ... The EMBO journal 34 (16), 2162-2181, 2015 | 40 | 2015 |
Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception F Bicker, V Vasic, G Horta, F Ortega, H Nolte, A Kavyanifar, S Keller, ... Nature communications 8 (1), 15922, 2017 | 36 | 2017 |