cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing C Uggenti, A Lepelley, M Depp, AP Badrock, MP Rodero, MT El-Daher, ... Nature Genetics 52 (12), 1364-1372, 2020 | 153 | 2020 |
In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord M Morsch, R Radford, A Lee, EK Don, AP Badrock, TE Hall, NJ Cole, ... Frontiers in cellular neuroscience 9, 321, 2015 | 126 | 2015 |
Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons AJ Svahn, EK Don, AP Badrock, NJ Cole, MB Graeber, JJ Yerbury, ... Acta neuropathologica 136, 445-459, 2018 | 79 | 2018 |
Autophagy induction is a Tor-and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis Y Boglev, AP Badrock, AJ Trotter, Q Du, EJ Richardson, AC Parslow, ... PLoS genetics 9 (2), e1003279, 2013 | 71 | 2013 |
A Tol2 gateway-compatible toolbox for the study of the nervous system and neurodegenerative disease EK Don, I Formella, AP Badrock, TE Hall, M Morsch, E Hortle, A Hogan, ... Zebrafish 14 (1), 69-72, 2017 | 66 | 2017 |
Zebrafish IL-4–like cytokines and IL-10 suppress inflammation but only IL-10 is essential for gill homeostasis F Bottiglione, CT Dee, R Lea, LAH Zeef, AP Badrock, M Wane, L Bugeon, ... The Journal of Immunology 205 (4), 994-1008, 2020 | 62 | 2020 |
RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation B Casar, AP Badrock, I Jiménez, I Arozarena, P Colón-Bolea, ... Nature communications 9 (1), 3595, 2018 | 37 | 2018 |
Enhanced fatty acid scavenging and glycerophospholipid metabolism accompany melanocyte neoplasia progression in zebrafish F Henderson, HR Johnston, AP Badrock, EA Jones, D Forster, ... Cancer research 79 (9), 2136-2151, 2019 | 35 | 2019 |
Using zebrafish larval models to study brain injury, locomotor and neuroinflammatory outcomes following intracerebral haemorrhage S Crilly, A Njegic, SE Laurie, E Fotiou, G Hudson, J Barrington, K Webb, ... F1000Research 7, 2018 | 32 | 2018 |
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached DJ Wilcock, AP Badrock, CW Wong, R Owen, M Guerin, AD Southam, ... Cell reports 39 (12), 2022 | 31 | 2022 |
Genetic basis of hindlimb loss in a naturally occurring vertebrate model EK Don, TA de Jong-Curtain, K Doggett, TE Hall, B Heng, AP Badrock, ... Biology open 5 (3), 359-366, 2016 | 31 | 2016 |
The Pu. 1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger MC Keightley, DP Carradice, JE Layton, L Pase, JY Bertrand, JG Wittig, ... Nature communications 8 (1), 14911, 2017 | 30 | 2017 |
Mutant human FUS Is ubiquitously mislocalized and generates persistent stress granules in primary cultured transgenic zebrafish cells JR Acosta, C Goldsbury, C Winnick, AP Badrock, ST Fraser, AS Laird, ... PLoS One 9 (6), e90572, 2014 | 30 | 2014 |
Leukoencephalopathy with calcifications and cysts: genetic and phenotypic spectrum YJ Crow, H Marshall, GI Rice, L Seabra, EM Jenkinson, K Baranano, ... American Journal of Medical Genetics Part A 185 (1), 15-25, 2021 | 26 | 2021 |
Analysis of U8 snoRNA variants in zebrafish reveals how bi-allelic variants cause leukoencephalopathy with calcifications and cysts AP Badrock, C Uggenti, L Wacheul, S Crilly, EM Jenkinson, GI Rice, ... The American Journal of Human Genetics 106 (5), 694-706, 2020 | 23 | 2020 |
Aurora kinase B regulates axonal outgrowth and regeneration in the spinal motor neurons of developing zebrafish SSL Gwee, RAW Radford, S Chow, MD Syal, M Morsch, I Formella, A Lee, ... Cellular and Molecular Life Sciences 75, 4269-4285, 2018 | 23 | 2018 |
In vivo validation of bimolecular fluorescence complementation (BiFC) to investigate aggregate formation in amyotrophic lateral sclerosis (ALS) EK Don, A Maschirow, RAW Radford, NM Scherer, A Vidal-Itriago, ... Molecular Neurobiology 58 (5), 2061-2074, 2021 | 10 | 2021 |
Osteoblasts contribute to a protective niche that supports melanoma cell proliferation and survival J Ferguson, DJ Wilcock, S McEntegart, AP Badrock, M Levesque, ... Pigment cell & melanoma research 33 (1), 74-85, 2020 | 8 | 2020 |
Global mapping of RNA homodimers in living cells MM Gabryelska, AP Badrock, JY Lau, RT O'Keefe, YJ Crow, G Kudla Genome Research 32 (5), 956-967, 2022 | 7 | 2022 |
Characterization of a mutant samhd1 zebrafish model implicates dysregulation of cholesterol biosynthesis in Aicardi-Goutières syndrome SE Withers, CF Rowlands, VS Tapia, F Hedley, IE Mosneag, S Crilly, ... Frontiers in Immunology 14, 1100967, 2023 | 3 | 2023 |