Defective cholesterol metabolism in amyotrophic lateral sclerosis J Abdel-Khalik, E Yutuc, PJ Crick, JÅ Gustafsson, M Warner, G Roman, ... Journal of lipid research 58 (1), 267-278, 2017 | 145 | 2017 |
Quantitative charge-tags for sterol and oxysterol analysis PJ Crick, T William Bentley, J Abdel-Khalik, I Matthews, PT Clayton, ... Clinical chemistry 61 (2), 400-411, 2015 | 101 | 2015 |
Simultaneous determination of endogenous steroid hormones in human and animal plasma and serum by liquid or gas chromatography coupled to tandem mass spectrometry J Abdel-Khalik, E Björklund, M Hansen Journal of Chromatography B 928, 58-77, 2013 | 89 | 2013 |
Cholesterol metabolites exported from human brain L Iuliano, PJ Crick, C Zerbinati, L Tritapepe, J Abdel-Khalik, M Poirot, ... Steroids 99, 189-193, 2015 | 88 | 2015 |
New methods for analysis of oxysterols and related compounds by LC–MS WJ Griffiths, J Abdel-Khalik, PJ Crick, E Yutuc, Y Wang The Journal of steroid biochemistry and molecular biology 162, 4-26, 2016 | 84 | 2016 |
Reduced plasma levels of 25-hydroxycholesterol and increased cerebrospinal fluid levels of bile acid precursors in multiple sclerosis patients PJ Crick, WJ Griffiths, J Zhang, M Beibel, J Abdel-Khalik, J Kuhle, ... Molecular neurobiology 54, 8009-8020, 2017 | 59 | 2017 |
Current trends in oxysterol research WJ Griffiths, J Abdel-Khalik, T Hearn, E Yutuc, AH Morgan, Y Wang Biochemical Society Transactions 44 (2), 652-658, 2016 | 57 | 2016 |
Cholesterolomics: an update WJ Griffiths, J Abdel-Khalik, E Yutuc, AH Morgan, I Gilmore, T Hearn, ... Analytical biochemistry 524, 56-67, 2017 | 54 | 2017 |
Metabolism of non-enzymatically derived oxysterols: clues from sterol metabolic disorders WJ Griffiths, E Yutuc, J Abdel-Khalik, PJ Crick, T Hearn, A Dickson, ... Free Radical Biology and Medicine 144, 124-133, 2019 | 49 | 2019 |
Sterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patients WJ Griffiths, J Abdel-Khalik, PJ Crick, M Ogundare, CH Shackleton, ... The Journal of steroid biochemistry and molecular biology 169, 77-87, 2017 | 48 | 2017 |
Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma WJ Griffiths, PJ Crick, A Meljon, S Theofilopoulos, J Abdel-Khalik, E Yutuc, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 40 | 2019 |
24 (S), 25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo S Theofilopoulos, WAA de Oliveira, S Yang, E Yutuc, A Saeed, ... Journal of Biological Chemistry 294 (11), 4169-4176, 2019 | 37 | 2019 |
Concentrations of bile acid precursors in cerebrospinal fluid of Alzheimer's disease patients WJ Griffiths, J Abdel-Khalik, E Yutuc, G Roman, M Warner, JÅ Gustafsson, ... Free Radical Biology and Medicine 134, 42-52, 2019 | 36 | 2019 |
Identification of unusual oxysterols and bile acids with 7-oxo or 3β, 5α, 6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage … WJ Griffiths, I Gilmore, E Yutuc, J Abdel-Khalik, PJ Crick, T Hearn, ... Journal of lipid research 59 (6), 1058-1070, 2018 | 25 | 2018 |
Charge-tagging liquid chromatography–mass spectrometry methodology targeting oxysterol diastereoisomers WJ Griffiths, T Hearn, PJ Crick, J Abdel-Khalik, A Dickson, E Yutuc, ... Chemistry and physics of lipids 207, 69-80, 2017 | 21 | 2017 |
Development of a solid phase extraction method for the simultaneous determination of steroid hormones in H295R cell line using liquid chromatography–tandem mass spectrometry J Abdel-Khalik, E Björklund, M Hansen Journal of Chromatography B 935, 61-69, 2013 | 19 | 2013 |
Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: potential importance of pathway intermediates J Abdel-Khalik, T Hearn, AL Dickson, PJ Crick, E Yutuc, K Austin-Muttitt, ... The Journal of steroid biochemistry and molecular biology 206, 105794, 2021 | 18 | 2021 |
Identification of 7α, 24-dihydroxy-3-oxocholest-4-en-26-oic and 7α, 25-dihydroxy-3-oxocholest-4-en-26-oic acids in human cerebrospinal fluid and plasma J Abdel-Khalik, PJ Crick, E Yutuc, AE DeBarber, PB Duell, RD Steiner, ... Biochimie 153, 86-98, 2018 | 17 | 2018 |
Studies on the analysis of 25-hydroxyvitamin D3 by isotope-dilution liquid chromatography–tandem mass spectrometry using enzyme-assisted derivatisation J Abdel-Khalik, PJ Crick, GD Carter, HL Makin, Y Wang, WJ Griffiths Biochemical and Biophysical Research Communications 446 (3), 745-750, 2014 | 16 | 2014 |
Formation and metabolism of oxysterols and cholestenoic acids found in the mouse circulation: Lessons learnt from deuterium-enrichment experiments and the CYP46A1 transgenic mouse PJ Crick, E Yutuc, J Abdel-Khalik, A Saeed, C Betsholtz, G Genove, ... The Journal of Steroid Biochemistry and Molecular Biology 195, 105475, 2019 | 14 | 2019 |