Stochasticity in gene expression: from theories to phenotypes M Kaern, TC Elston, WJ Blake, JJ Collins Nature Reviews Genetics 6 (6), 451-464, 2005 | 2750 | 2005 |
Noise in eukaryotic gene expression WJ Blake, M Kærn, CR Cantor, JJ Collins Nature 422 (6932), 633-637, 2003 | 1965 | 2003 |
Programmable cells: interfacing natural and engineered gene networks H Kobayashi, M Kaern, M Araki, K Chung, TS Gardner, CR Cantor, ... Proceedings of the National Academy of Sciences 101 (22), 8414-8419, 2004 | 793 | 2004 |
A chance at survival: gene expression noise and phenotypic diversification strategies D Fraser, M Kaern Molecular microbiology 71 (6), 1333-1340, 2009 | 276 | 2009 |
The engineering of gene regulatory networks M Kaern, WJ Blake, JJ Collins Annual review of biomedical engineering 5 (1), 179-206, 2003 | 272 | 2003 |
The circadian molecular clock regulates adult hippocampal neurogenesis by controlling the timing of cell-cycle entry and exit P Bouchard-Cannon, L Mendoza-Viveros, A Yuen, M Kærn, HYM Cheng Cell reports 5 (4), 961-973, 2013 | 174 | 2013 |
Estimations of intrinsic and extrinsic noise in models of nonlinear genetic networks M Scott, B Ingalls, M Kærn Chaos: An Interdisciplinary Journal of Nonlinear Science 16 (2), 2006 | 137 | 2006 |
Synchrony in a population of hysteresis-based genetic oscillators A Kuznetsov, M Kærn, N Kopell SIAM Journal on Applied Mathematics 65 (2), 392-425, 2004 | 136 | 2004 |
A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics REC Lee, LG Puente, M Kærn, LA Megeney PloS one 3 (8), e2956, 2008 | 110 | 2008 |
Flow-distributed oscillations: stationary chemical waves in a reacting flow M Kærn, M Menzinger Physical Review E 60 (4), R3471, 1999 | 91 | 1999 |
Gene expression noise facilitates adaptation and drug resistance independently of mutation DA Charlebois, N Abdennur, M Kaern Physical review letters 107 (21), 218101, 2011 | 89 | 2011 |
Improvement of the reverse tetracycline transactivator by single amino acid substitutions that reduce leaky target gene expression to undetectable levels IJ Roney, AD Rudner, JF Couture, M Kærn Scientific reports 6 (1), 27697, 2016 | 71 | 2016 |
Segmentation and somitogenesis derived from phase dynamics in growing oscillatory media M Kærn, M Menzinger, A Hunding Journal of theoretical biology 207 (4), 473-493, 2000 | 70 | 2000 |
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing R Arulanandam, C Batenchuk, O Varette, C Zakaria, V Garcia, NE Forbes, ... Nature communications 6 (1), 6410, 2015 | 62 | 2015 |
Estimating the stochastic bifurcation structure of cellular networks C Song, H Phenix, V Abedi, M Scott, BP Ingalls, M Kærn, TJ Perkins PLoS computational biology 6 (3), e1000699, 2010 | 55 | 2010 |
Model-based rational design of an oncolytic virus with improved therapeutic potential F Le Bœuf, C Batenchuk, M Vähä-Koskela, S Breton, D Roy, C Lemay, ... Nature communications 4 (1), 1974, 2013 | 54 | 2013 |
Chemical waves in open flows of active media: their relevance to axial segmentation in biology M Kærn, M Menzinger, R Satnoianu, A Hunding Faraday discussions 120, 295-312, 2002 | 53 | 2002 |
Coherent feedforward transcriptional regulatory motifs enhance drug resistance DA Charlebois, G Balázsi, M Kærn Physical Review E 89 (5), 052708, 2014 | 42 | 2014 |
Genome‐wide association between Six4, MyoD, and the histone demethylase Utx during myogenesis I Chakroun, D Yang, J Girgis, A Gunasekharan, H Phenix, M Kærn, ... The FASEB Journal 29 (11), 4738-4755, 2015 | 37 | 2015 |
Chromosomal position effects are linked to sir2-mediated variation in transcriptional burst size C Batenchuk, S St-Pierre, L Tepliakova, S Adiga, A Szuto, N Kabbani, ... Biophysical journal 100 (10), L56-L58, 2011 | 36 | 2011 |