Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart R Gredilla, A Sanz, M Lopez-Torres, G Barja The FASEB Journal 15 (9), 1589-1591, 2001 | 453 | 2001 |
Effects of aging and caloric restriction on mitochondrial energy production in gastrocnemius muscle and heart B Drew, S Phaneuf, A Dirks, C Selman, R Gredilla, A Lezza, G Barja, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2003 | 332 | 2003 |
Minireview: the role of oxidative stress in relation to caloric restriction and longevity R Gredilla, G Barja Endocrinology 146 (9), 3713-3717, 2005 | 326 | 2005 |
Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria M López-Torres, R Gredilla, A Sanz, G Barja Free Radical Biology and Medicine 32 (9), 882-889, 2002 | 325 | 2002 |
Role of estrogen and other sex hormones in brain aging. Neuroprotection and DNA repair S Zárate, T Stevnsner, R Gredilla Frontiers in aging neuroscience 9, 322754, 2017 | 265 | 2017 |
Dietary restriction at old age lowers mitochondrial oxygen radical production and leak at complex I and oxidative DNA damage in rat brain A Sanz, P Caro, J Ibañez, J Gómez, R Gredilla, G Barja Journal of bioenergetics and biomembranes 37, 83-90, 2005 | 200 | 2005 |
Effect of short-term caloric restriction on H2O2 production and oxidative DNA damage in rat liver mitochondria and location of the free radical source R Gredilla, G Barja, M López-Torres Journal of bioenergetics and biomembranes 33, 279-287, 2001 | 191 | 2001 |
Mitochondrial DNA repair and association with aging–an update R Gredilla, VA Bohr, T Stevnsner Experimental gerontology 45 (7-8), 478-488, 2010 | 175 | 2010 |
Mitochondria and oxidative stress in heart aging B Martín-Fernández, R Gredilla Age 38 (4), 225-238, 2016 | 163 | 2016 |
Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls R Pamplona, M Portero-Otı́n, J Requena, R Gredilla, G Barja Mechanisms of ageing and development 123 (11), 1437-1446, 2002 | 151 | 2002 |
Double bond content of phospholipids and lipid peroxidation negatively correlate with maximum longevity in the heart of mammals R Pamplona, M Portero-Otın, C Ruiz, R Gredilla, A Herrero, G Barja Mechanisms of ageing and development 112 (3), 169-183, 2000 | 151 | 2000 |
Effects of fasting on oxidative stress in rat liver mitochondria M Sorensen, A Sanz, J Gomez, R Pamplona, M Portero-Otin, R Gredilla, ... Free Radical Research 40 (4), 339-347, 2006 | 118 | 2006 |
DNA damage and base excision repair in mitochondria and their role in aging R Gredilla Journal of aging research 2011 (1), 257093, 2011 | 115 | 2011 |
Heart fatty acid unsaturation and lipid peroxidation, and aging rate, are lower in the canary and the parakeet than in the mouse R Pamplona, M Portero-Otin, D Riba, F Ledo, R Gredilla, A Herrero, ... Aging Clinical and Experimental Research 11, 44-49, 1999 | 110 | 1999 |
Mitochondrial free radical generation and lifespan control in the fungal aging model Podospora anserina R Gredilla, J Grief, HD Osiewacz Experimental gerontology 41 (4), 439-447, 2006 | 96 | 2006 |
Influence of hyper‐and hypothyroidism on lipid peroxidation, unsaturation of phospholipids, glutathione system and oxidative damage to nuclear and mitochondrial DNA in mice … R Gredilla, M Lopez Torres, M Portero‐Otín, R Pamplona, G Barja Molecular and cellular biochemistry 221, 41-48, 2001 | 94 | 2001 |
Aging increases N epsilon-(carboxymethyl) lysine and caloric restriction decreases N epsilon-(carboxyethyl) lysine and N epsilon-(malondialdehyde) lysine in rat heart … R Pamplona, M Portero-OtÍn, MJ Bellmunt, R Gredilla, G Barja Free radical research 36 (1), 47-54, 2002 | 93 | 2002 |
Effect of insulin and growth hormone on rat heart and liver oxidative stress in control and caloric restricted animals A Sanz, R Gredilla, R Pamplona, M Portero-Otin, E Vara, JAF Tresguerres, ... Biogerontology 6, 15-26, 2005 | 83 | 2005 |
Thyroid hormone-induced oxidative damage on lipids, glutathione and DNA in the mouse heart R Gredilla, G Barja, M López-Torres Free radical research 35 (4), 417-425, 2001 | 83 | 2001 |
Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions R Gredilla, C Garm, R Holm, VA Bohr, T Stevnsner Neurobiology of aging 31 (6), 993-1002, 2010 | 73 | 2010 |