The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43 I Kimura, K Ozawa, D Inoue, T Imamura, K Kimura, T Maeda, K Terasawa, ... Nature communications 4 (1), 1829, 2013 | 1457 | 2013 |
Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41) I Kimura, D Inoue, T Maeda, T Hara, A Ichimura, S Miyauchi, M Kobayashi, ... Proceedings of the national academy of sciences 108 (19), 8030-8035, 2011 | 1051 | 2011 |
Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation M Kasubuchi, S Hasegawa, T Hiramatsu, A Ichimura, I Kimura Nutrients 7 (4), 2839-2849, 2015 | 850 | 2015 |
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human A Ichimura, A Hirasawa, O Poulain-Godefroy, A Bonnefond, T Hara, ... Nature 483 (7389), 350-354, 2012 | 740 | 2012 |
Free fatty acid receptors in health and disease I Kimura, A Ichimura, R Ohue-Kitano, M Igarashi Physiological reviews, 2019 | 642 | 2019 |
Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice I Kimura, J Miyamoto, R Ohue-Kitano, K Watanabe, T Yamada, M Onuki, ... Science 367 (6481), eaaw8429, 2020 | 313 | 2020 |
Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids J Miyamoto, M Igarashi, K Watanabe, S Karaki, H Mukouyama, S Kishino, ... Nature communications 10 (1), 4007, 2019 | 272 | 2019 |
The SCFA receptor GPR43 and energy metabolism I Kimura, D Inoue, K Hirano, G Tsujimoto Frontiers in endocrinology 5, 93736, 2014 | 271 | 2014 |
A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway J Miyamoto, T Mizukure, SB Park, S Kishino, I Kimura, K Hirano, ... Journal of Biological Chemistry 290 (5), 2902-2918, 2015 | 231 | 2015 |
Gut microbiota dysbiosis drives and implies novel therapeutic strategies for diabetes mellitus and related metabolic diseases X Li, K Watanabe, I Kimura Frontiers in immunology 8, 318312, 2017 | 195 | 2017 |
Nutritional signaling via free fatty acid receptors J Miyamoto, S Hasegawa, M Kasubuchi, A Ichimura, A Nakajima, I Kimura International journal of molecular sciences 17 (4), 450, 2016 | 195 | 2016 |
Role of free fatty acid receptors in the regulation of energy metabolism T Hara, D Kashihara, A Ichimura, I Kimura, G Tsujimoto, A Hirasawa Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 190 | 2014 |
Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders T Hara, A Hirasawa, A Ichimura, I Kimura, G Tsujimoto Journal of pharmaceutical sciences 100 (9), 3594-3601, 2011 | 188 | 2011 |
Free fatty acid receptors as therapeutic targets for the treatment of diabetes A Ichimura, S Hasegawa, M Kasubuchi, I Kimura Frontiers in pharmacology 5, 118349, 2014 | 186 | 2014 |
GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites N Morita, E Umemoto, S Fujita, A Hayashi, J Kikuta, I Kimura, T Haneda, ... Nature 566 (7742), 110-114, 2019 | 185 | 2019 |
Circadian regulation of intracellular G-protein signalling mediates intercellular synchrony and rhythmicity in the suprachiasmatic nucleus M Doi, A Ishida, A Miyake, M Sato, R Komatsu, F Yamazaki, I Kimura, ... Nature communications 2 (1), 327, 2011 | 159 | 2011 |
Free fatty acid receptors and their role in regulation of energy metabolism T Hara, I Kimura, D Inoue, A Ichimura, A Hirasawa Reviews of Physiology, Biochemistry and Pharmacology, Vol. 164, 77-116, 2013 | 150 | 2013 |
Chemotherapeutic results and prognostic factors of patients with advanced non-Hodgkin's lymphoma treated with VEPA or VEPA-M. M Shimoyama, K Ota, M Kikuchi, K Yunoki, S Konda, K Takatsuki, ... Journal of Clinical Oncology 6 (1), 128-141, 1988 | 147 | 1988 |
The role of short-chain fatty acid on blood pressure regulation J Miyamoto, M Kasubuchi, A Nakajima, J Irie, H Itoh, I Kimura Current Opinion in Nephrology and Hypertension 25 (5), 379-383, 2016 | 140 | 2016 |
Barley β-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice J Miyamoto, K Watanabe, S Taira, M Kasubuchi, X Li, J Irie, H Itoh, ... PLoS One 13 (4), e0196579, 2018 | 131 | 2018 |