| Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility MF Carlier, V Laurent, J Santolini, R Melki, D Didry, GX Xia, Y Hong, ... The Journal of cell biology 136 (6), 1307-1322, 1997 | 1289 | 1997 |
| α-Synuclein strains cause distinct synucleinopathies after local and systemic administration W Peelaerts, L Bousset, A Van der Perren, A Moskalyuk, R Pulizzi, ... Nature 522 (7556), 340-344, 2015 | 1186 | 2015 |
| α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells C Hansen, E Angot, AL Bergström, JA Steiner, L Pieri, G Paul, TF Outeiro, ... The Journal of clinical investigation 121 (2), 715-725, 2011 | 964 | 2011 |
| Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats S Holmqvist, O Chutna, L Bousset, P Aldrin-Kirk, W Li, T Björklund, ... Acta neuropathologica 128, 805-820, 2014 | 962 | 2014 |
| Prion-like transmission of protein aggregates in neurodegenerative diseases P Brundin, R Melki, R Kopito Nature reviews Molecular cell biology 11 (4), 301-307, 2010 | 947 | 2010 |
| Structural and functional characterization of two alpha-synuclein strains L Bousset, L Pieri, G Ruiz-Arlandis, J Gath, PH Jensen, B Habenstein, ... Nature communications 4 (1), 2575, 2013 | 913 | 2013 |
| G51D α‐synuclein mutation causes a novel Parkinsonian–pyramidal syndrome S Lesage, M Anheim, F Letournel, L Bousset, A Honoré, N Rozas, L Pieri, ... Annals of neurology 73 (4), 459-471, 2013 | 856 | 2013 |
| Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates PH Ren, JE Lauckner, I Kachirskaia, JE Heuser, R Melki, RR Kopito Nature cell biology 11 (2), 219-225, 2009 | 489 | 2009 |
| Neuron‐to‐neuron transmission of α‐synuclein fibrils through axonal transport EC Freundt, N Maynard, EK Clancy, S Roy, L Bousset, Y Sourigues, ... Annals of neurology 72 (4), 517-524, 2012 | 408 | 2012 |
| Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes S Abounit, L Bousset, F Loria, S Zhu, F de Chaumont, L Pieri, ... The EMBO journal 35 (19), 2120-2138, 2016 | 362 | 2016 |
| Structure-function studies on small heat shock protein oligomeric assembly and interaction with unfolded polypeptides MR Leroux, R Melki, B Gordon, G Batelier, EPM Candido Journal of Biological Chemistry 272 (39), 24646-24656, 1997 | 304 | 1997 |
| Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice NL Rey, GH Petit, L Bousset, R Melki, P Brundin Acta neuropathologica 126, 555-573, 2013 | 297 | 2013 |
| Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells L Pieri, K Madiona, L Bousset, R Melki Biophysical journal 102 (12), 2894-2905, 2012 | 288 | 2012 |
| Prying into the prion hypothesis for Parkinson's disease P Brundin, R Melki Journal of Neuroscience 37 (41), 9808-9818, 2017 | 286 | 2017 |
| Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies M Tardivel, S Bégard, L Bousset, S Dujardin, A Coens, R Melki, L Buée, ... Acta neuropathologica communications 4, 1-14, 2016 | 285 | 2016 |
| Alpha‐synuclein transfers from neurons to oligodendrocytes JF Reyes, NL Rey, L Bousset, R Melki, P Brundin, E Angot Glia 62 (3), 387-398, 2014 | 281 | 2014 |
| Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy R Guerrero-Ferreira, NMI Taylor, AA Arteni, P Kumari, D Mona, P Ringler, ... Elife 8, e48907, 2019 | 278 | 2019 |
| Ectosomes: a new mechanism for non-exosomal secretion of tau protein S Dujardin, S Bégard, R Caillierez, C Lachaud, L Delattre, S Carrier, ... PloS one 9 (6), e100760, 2014 | 247 | 2014 |
| α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities P Alam, L Bousset, R Melki, DE Otzen Journal of neurochemistry 150 (5), 522-534, 2019 | 246 | 2019 |
| Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins WP Flavin, L Bousset, ZC Green, Y Chu, S Skarpathiotis, MJ Chaney, ... Acta neuropathologica 134, 629-653, 2017 | 237 | 2017 |
Patrik BrundinHoffmann-La Roche AG在 roche.com 的电子邮件经过验证
