| Clodronate and liposome‐encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′‐(β, γ‐dichloromethylene) triphosphate, by mammalian cells in vitro JC Frith, J Mönkkönen, GM Blackburn, RGG Russell, MJ Rogers Journal of Bone and Mineral Research 12 (9), 1358-1367, 1997 | 627 | 1997 |
| Biochemical and molecular mechanisms of action of bisphosphonates MJ Rogers, JC Crockett, FP Coxon, J Mönkkönen Bone 49 (1), 34-41, 2011 | 616 | 2011 |
| Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset C Harly, Y Guillaume, S Nedellec, CM Peigné, H Mönkkönen, ... Blood, The Journal of the American Society of Hematology 120 (11), 2269-2279, 2012 | 579 | 2012 |
| Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite PP Lehenkari, M Kellinsalmi, JP Näpänkangas, KV Ylitalo, J Mönkkönen, ... Molecular pharmacology 61 (5), 1255-1262, 2002 | 470 | 2002 |
| Human breast cancer cells educate macrophages toward the M2 activation status S Sousa, R Brion, M Lintunen, P Kronqvist, J Sandholm, J Mönkkönen, ... Breast cancer research 17, 1-14, 2015 | 411 | 2015 |
| The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption … JC Frith, J Mönkkönen, S Auriola, H Mönkkönen, MJ Rogers Arthritis & Rheumatism: Official Journal of the American College of …, 2001 | 368 | 2001 |
| Molecular mechanisms of action of bisphosphonates MJ Rogers, JC Frith, SP Luckman, FP Coxon, HL Benford, J Monkkonen, ... Bone 24 (5), 73S-79S, 1999 | 363 | 1999 |
| A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen‐containing … H Mönkkönen, S Auriola, P Lehenkari, M Kellinsalmi, IE Hassinen, ... British journal of pharmacology 147 (4), 437-445, 2006 | 358 | 2006 |
| Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs HL Benford, JC Frith, S Auriola, J Mönkkönen, MJ Rogers Molecular pharmacology 56 (1), 131-140, 1999 | 336 | 1999 |
| Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP AJ Roelofs, M Jauhiainen, H Mönkkönen, MJ Rogers, J Mönkkönen, ... British journal of haematology 144 (2), 245-250, 2009 | 327 | 2009 |
| Interaction of liposomes with human skin in vitro—the influence of lipid composition and structure M Kirjavainen, A Urtti, I Jääskeläinen, TM Suhonen, P Paronen, ... Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1304 (3 …, 1996 | 323 | 1996 |
| Transferrin mediated solid lipid nanoparticles containing curcumin: enhanced in vitro anticancer activity by induction of apoptosis RS Mulik, J Mönkkönen, RO Juvonen, KR Mahadik, AR Paradkar International journal of pharmaceutics 398 (1-2), 190-203, 2010 | 316 | 2010 |
| Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages. KS Selander, J Mönkkönen, EK Karhukorpi, P Härkönen, R Hannuniemi, ... Molecular pharmacology 50 (5), 1127-1138, 1996 | 309 | 1996 |
| Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories R Hayeshi, C Hilgendorf, P Artursson, P Augustijns, B Brodin, ... European Journal of Pharmaceutical Sciences 35 (5), 383-396, 2008 | 296 | 2008 |
| Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits HD Danenberg, I Fishbein, J Gao, J Mönkkönen, R Reich, I Gati, ... Circulation 106 (5), 599-605, 2002 | 296 | 2002 |
| Effect of liposomal and free bisphosphonates on the IL-1β, IL-6 and TNFα secretion from RAW 264 cells in vitro N Pennanen, S Lapinjoki, A Urtti, J Mönkkönen Pharmaceutical research 12, 916-922, 1995 | 287 | 1995 |
| Liposome–skin interactions and their effects on the skin permeation of drugs M Kirjavainen, A Urtti, R Valjakka-Koskela, J Kiesvaara, J Mönkkönen European journal of pharmaceutical sciences 7 (4), 279-286, 1999 | 236 | 1999 |
| Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells H Wang, O Henry, MD Distefano, YC Wang, J Räikkönen, J Mönkkönen, ... The Journal of Immunology 191 (3), 1029-1042, 2013 | 191 | 2013 |
| Phospholipids affect stratum corneum lipid bilayer fluidity and drug partitioning into the bilayers M Kirjavainen, J Mönkkönen, M Saukkosaari, R Valjakka-Koskela, ... Journal of controlled release 58 (2), 207-214, 1999 | 190 | 1999 |
| Measurement of hydration in the stratum corneum with the MoistureMeter and comparison with the Corneometer E Alanen, J Nuutinen, K Nicklén, T Lahtinen, J Mönkkönen Skin Research and Technology 10 (1), 32-37, 2004 | 185 | 2004 |
