Antibody–PROTAC conjugates enable HER2-dependent targeted protein degradation of BRD4 M Maneiro, N Forte, MM Shchepinova, CS Kounde, V Chudasama, ... ACS chemical biology 15 (6), 1306-1312, 2020 | 198 | 2020 |
Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis M Morais, JPM Nunes, K Karu, N Forte, I Benni, MEB Smith, S Caddick, ... Organic & Biomolecular Chemistry 15 (14), 2947-2952, 2017 | 88 | 2017 |
Site-selective lysine conjugation methods and applications towards antibody–drug conjugates M Haque, N Forte, JR Baker Chemical Communications 57 (82), 10689-10702, 2021 | 59 | 2021 |
Tuning the hydrolytic stability of next generation maleimide cross-linkers enables access to albumin-antibody fragment conjugates and tri-scFvs N Forte, M Livanos, E Miranda, M Morais, X Yang, VS Rajkumar, ... Bioconjugate Chemistry 29 (2), 486-492, 2018 | 56 | 2018 |
Homogeneous antibody-drug conjugates via site-selective disulfide bridging N Forte, V Chudasama, JR Baker Drug Discovery Today: Technologies 30, 11-20, 2018 | 50 | 2018 |
Cysteine-to-lysine transfer antibody fragment conjugation N Forte, I Benni, K Karu, V Chudasama, JR Baker Chemical Science 10 (47), 10919-10924, 2019 | 28 | 2019 |
One-pot thiol–amine bioconjugation to maleimides: simultaneous stabilisation and dual functionalisation A Wall, AG Wills, N Forte, C Bahou, L Bonin, K Nicholls, MT Ma, ... Chemical Science 11 (42), 11455-11460, 2020 | 21 | 2020 |
Targeted protein degradation through E2 recruitment N Forte, D Dovala, MJ Hesse, JM McKenna, JA Tallarico, M Schirle, ... ACS chemical biology 18 (4), 897-904, 2023 | 20 | 2023 |
Application of next-generation maleimides (NGMs) to site-selective antibody conjugation M Morais, N Forte, V Chudasama, JR Baker Bioconjugation: Methods and Protocols, 15-24, 2019 | 12 | 2019 |
New Bifunctional Chelators Incorporating Dibromomaleimide Groups for Radiolabeling of Antibodies with Positron Emission Tomography Imaging Radioisotopes M Farleigh, TT Pham, Z Yu, J Kim, K Sunassee, G Firth, N Forte, ... Bioconjugate Chemistry 32 (7), 1214-1222, 2021 | 7 | 2021 |
A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold RJ Spears, C McMahon, M Shamsabadi, C Bahou, IA Thanasi, ... Chemical Communications 58 (5), 645-648, 2022 | 5 | 2022 |
The Nitrile Bis-Thiol Bioconjugation Reaction M Patel, N Forte, CR Bishop, MJ Porter, M Dagwell, K Karu, ... Journal of the American Chemical Society 146 (1), 274-280, 2023 | | 2023 |
Covalent Degrader of the Oncogenic Transcription Factor β-Catenin FA Gowans, N Forte, J Hatcher, OW Huang, Y Wang, ... Journal of the American Chemical Society, 2023 | | 2023 |
King’s Research Portal M Farleigh, T Pham, Z Yu, J Kim, K Sunassee, G Firth, N Forte, ... | | |
New bifunctional chelators incorporating dibromomaleimide groups for radiolabeling of antibodies with PET imaging radioisotopes M Farleigh, TT Pham, Z Yu, J Kim, K Sunassee, G Firth, N Forte, ... | | |