Direct gating of the TRPM2 channel by cADPR via specific interactions with the ADPR binding pocket P Yu, Z Liu, X Yu, P Ye, H Liu, X Xue, L Yang, Z Li, Y Wu, C Fang, YJ Zhao, ... Cell reports 27 (12), 3684-3695. e4, 2019 | 73 | 2019 |
Identification and characterization of benzo [d] oxazol-2 (3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL L Yang, Y Liu, M Fan, G Zhu, H Jin, J Liang, Z Liu, Z Huang, L Zhang European Journal of Medicinal Chemistry 182, 111656, 2019 | 20 | 2019 |
Discovery and antibacterial study of potential PPK1 inhibitors against uropathogenic E. coli L Peng, L Zeng, H Jin, L Yang, Y Xiao, Z Lan, Z Yu, S Ouyang, L Zhang, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 1224-1232, 2020 | 16 | 2020 |
Effects of coal-fired PM2.5 on the expression levels of atherosclerosis-related proteins and the phosphorylation level of MAPK in ApoE−/− mice S Wang, F Wang, L Yang, Q Li, Y Huang, Z Cheng, H Chu, Y Song, ... BMC Pharmacology and Toxicology 21, 1-11, 2020 | 15 | 2020 |
Rational design and identification of small‐molecule allosteric inhibitors of CD38 L Yang, T Li, S Li, Y Wu, X Shi, H Jin, Z Liu, Y Zhao, L Zhang, HC Lee, ... ChemBioChem 20 (19), 2485-2493, 2019 | 7 | 2019 |
Effective Inhibition of TDP‐43 Aggregation by Native State Stabilization L Yang, Y Jasiqi, A Zettor, O Vadas, J Chiaravalli, F Agou, HA Lashuel Angewandte Chemie 136 (3), e202314587, 2024 | 4 | 2024 |
Recombinant Full-Length TDP-43 Oligomers Retain Their Ability to Bind RNAs, Are Not Toxic, and Do Not Seed TDP-43 Aggregation in Vitro L Yang, Y Jasiqi, H Lashuel ACS Chemical Neuroscience 15 (1), 193-204, 2023 | 1 | 2023 |
Transactive response dna-binding protein 43kda (tdp-43) mutants and uses thereof L Yang, H Lashuel | | 2024 |