Impaired function of circulating CD34+ CD45− cells in patients with proliferative diabetic retinopathy K Tan, E Lessieur, A Cutler, P Nerone, A Vasanji, K Asosingh, S Erzurum, ... Experimental eye research 91 (2), 229-237, 2010 | 84 | 2010 |
Successful induction of diabetes in mice demonstrates no gender difference in development of early diabetic retinopathy A Saadane, EM Lessieur, Y Du, H Liu, TS Kern PLoS One 15 (9), e0238727, 2020 | 74 | 2020 |
Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy H Liu, EM Lessieur, A Saadane, SI Lindstrom, PR Taylor, TS Kern Diabetologia 62, 2365-2374, 2019 | 47 | 2019 |
Ciliary genes arl13b, ahi1 and cc2d2a differentially modify expression of visual acuity phenotypes but do not enhance retinal degeneration due to mutation of cep290 in zebrafish EM Lessieur, P Song, GC Nivar, EM Piccillo, J Fogerty, R Rozic, ... PloS one 14 (4), e0213960, 2019 | 43 | 2019 |
Nanomedicine platform for targeting activated neutrophils and neutrophil–platelet complexes using an α1-antitrypsin-derived peptide motif MA Cruz, D Bohinc, EA Andraska, J Alvikas, S Raghunathan, NA Masters, ... Nature nanotechnology 17 (9), 1004-1014, 2022 | 41 | 2022 |
The ciliopathy gene ahi1 is required for zebrafish cone photoreceptor outer segment morphogenesis and survival EM Lessieur, J Fogerty, RJ Gaivin, P Song, BD Perkins Investigative ophthalmology & visual science 58 (1), 448-460, 2017 | 39 | 2017 |
Neutrophil-derived proteases contribute to the pathogenesis of early diabetic retinopathy EM Lessieur, H Liu, A Saadane, Y Du, J Tang, J Kiser, TS Kern Investigative Ophthalmology & Visual Science 62 (13), 7-7, 2021 | 24 | 2021 |
CCR2-positive monocytes contribute to the pathogenesis of early diabetic retinopathy in mice A Saadane, AA Veenstra, MS Minns, J Tang, Y Du, F Abubakr Elghazali, ... Diabetologia 66 (3), 590-602, 2023 | 14 | 2023 |
The adult zebrafish retina: in vivo optical sectioning with confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography BA Bell, A Yuan, RM Dicicco, J Fogerty, EM Lessieur, BD Perkins Experimental eye research 153, 65-78, 2016 | 14 | 2016 |
Photoreceptor cell calcium dysregulation and calpain activation promote pathogenic photoreceptor oxidative stress and inflammation in prodromal diabetic retinopathy A Saadane, Y Du, WB Thoreson, M Miyagi, EM Lessieur, J Kiser, X Wen, ... The American journal of pathology 191 (10), 1805-1821, 2021 | 13 | 2021 |
ICAM-1 on the luminal surface of endothelial cells is induced to a greater extent in mouse retina than in other tissues in diabetes EM Lessieur, H Liu, A Saadane, Y Du, J Kiser, TS Kern Diabetologia 65 (10), 1734-1744, 2022 | 11 | 2022 |
Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition JC Luu, A Saadane, H Leinonen, EH Choi, F Gao, D Lewandowski, ... Proceedings of the National Academy of Sciences 120 (19), e2221045120, 2023 | 6 | 2023 |
Mechanical regulation of retinal vascular inflammation and degeneration in diabetes S Chandrakumar, I Santiago Tierno, M Agarwal, EM Lessieur, Y Du, ... Diabetes 73 (2), 280-291, 2024 | 3 | 2024 |
Lysyl oxidase promotes neutrophil cytotoxicity towards retinal endothelial cells in diabetes M Agarwal, S Chandrakumar, IS Tierno, A Chandra, EM Lessieur, ... Investigative Ophthalmology & Visual Science 64 (8), 499-499, 2023 | 1 | 2023 |
Retinal vascular stiffening contributes to leukocyte-mediated endothelial apoptosis in diabetes S Chandrakumar, IS Tierno, M Agarwal, E Lessieur, H Liu, TS Kern, ... Investigative Ophthalmology & Visual Science 63 (7), 3595–A0050-3595–A0050, 2022 | 1 | 2022 |
Partial deletion of Lrat inhibits prodromal characteristics of diabetic retinopathy EM Lessieur, Y Du, A Saadane, H Liu, J Kiser, TS Kern Investigative Ophthalmology & Visual Science 63 (7), 3590–A0045-3590–A0045, 2022 | 1 | 2022 |
Actin remodeling governs neutrophil activation: Implications for retinal capillary degeneration in diabetic retinopathy. M Agarwal, S Chandrakumar, IS Tierno, EM Lessieur, TS Kern, K Ghosh Investigative Ophthalmology & Visual Science 65 (7), 881-881, 2024 | | 2024 |
Neutrophil-derived extracellular vesicles from diabetic mice promote retinal endothelial cell cytotoxicity EM Lessieur, F Gao, Y Du, J Jiyacharoen, J Kiser, TS Kern Investigative Ophthalmology & Visual Science 64 (8), 1844-1844, 2023 | | 2023 |
Mechanical regulation of retinal vascular inflammation and degeneration in diabetic retinopathy S Chandrakumar, IS Tierno, M Agarwal, EM Lessieur, Y Du, J Tang, ... bioRxiv, 2022.12. 18.520943, 2022 | | 2022 |
Deficiency in classical monocytes prevents superoxide, inflammation and retinal vascular lesions in diabetic mice A Saadane, AA Veenstra, M Minns, Y Du, E Lessieur, TS Kern Investigative Ophthalmology & Visual Science 63 (7), 949–A0418-949–A0418, 2022 | | 2022 |