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Emma M Lessieur
Emma M Lessieur
Postdoctoral Scholar, University of California Irvine
在 hs.uci.edu 的电子邮件经过验证
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引用次数
引用次数
年份
Impaired function of circulating CD34+ CD45− cells in patients with proliferative diabetic retinopathy
K Tan, E Lessieur, A Cutler, P Nerone, A Vasanji, K Asosingh, S Erzurum, ...
Experimental eye research 91 (2), 229-237, 2010
842010
Successful induction of diabetes in mice demonstrates no gender difference in development of early diabetic retinopathy
A Saadane, EM Lessieur, Y Du, H Liu, TS Kern
PLoS One 15 (9), e0238727, 2020
742020
Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy
H Liu, EM Lessieur, A Saadane, SI Lindstrom, PR Taylor, TS Kern
Diabetologia 62, 2365-2374, 2019
472019
Ciliary genes arl13b, ahi1 and cc2d2a differentially modify expression of visual acuity phenotypes but do not enhance retinal degeneration due to mutation of cep290 in zebrafish
EM Lessieur, P Song, GC Nivar, EM Piccillo, J Fogerty, R Rozic, ...
PloS one 14 (4), e0213960, 2019
432019
Nanomedicine platform for targeting activated neutrophils and neutrophil–platelet complexes using an α1-antitrypsin-derived peptide motif
MA Cruz, D Bohinc, EA Andraska, J Alvikas, S Raghunathan, NA Masters, ...
Nature nanotechnology 17 (9), 1004-1014, 2022
412022
The ciliopathy gene ahi1 is required for zebrafish cone photoreceptor outer segment morphogenesis and survival
EM Lessieur, J Fogerty, RJ Gaivin, P Song, BD Perkins
Investigative ophthalmology & visual science 58 (1), 448-460, 2017
392017
Neutrophil-derived proteases contribute to the pathogenesis of early diabetic retinopathy
EM Lessieur, H Liu, A Saadane, Y Du, J Tang, J Kiser, TS Kern
Investigative Ophthalmology & Visual Science 62 (13), 7-7, 2021
242021
CCR2-positive monocytes contribute to the pathogenesis of early diabetic retinopathy in mice
A Saadane, AA Veenstra, MS Minns, J Tang, Y Du, F Abubakr Elghazali, ...
Diabetologia 66 (3), 590-602, 2023
142023
The adult zebrafish retina: in vivo optical sectioning with confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography
BA Bell, A Yuan, RM Dicicco, J Fogerty, EM Lessieur, BD Perkins
Experimental eye research 153, 65-78, 2016
142016
Photoreceptor cell calcium dysregulation and calpain activation promote pathogenic photoreceptor oxidative stress and inflammation in prodromal diabetic retinopathy
A Saadane, Y Du, WB Thoreson, M Miyagi, EM Lessieur, J Kiser, X Wen, ...
The American journal of pathology 191 (10), 1805-1821, 2021
132021
ICAM-1 on the luminal surface of endothelial cells is induced to a greater extent in mouse retina than in other tissues in diabetes
EM Lessieur, H Liu, A Saadane, Y Du, J Kiser, TS Kern
Diabetologia 65 (10), 1734-1744, 2022
112022
Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition
JC Luu, A Saadane, H Leinonen, EH Choi, F Gao, D Lewandowski, ...
Proceedings of the National Academy of Sciences 120 (19), e2221045120, 2023
62023
Mechanical regulation of retinal vascular inflammation and degeneration in diabetes
S Chandrakumar, I Santiago Tierno, M Agarwal, EM Lessieur, Y Du, ...
Diabetes 73 (2), 280-291, 2024
32024
Lysyl oxidase promotes neutrophil cytotoxicity towards retinal endothelial cells in diabetes
M Agarwal, S Chandrakumar, IS Tierno, A Chandra, EM Lessieur, ...
Investigative Ophthalmology & Visual Science 64 (8), 499-499, 2023
12023
Retinal vascular stiffening contributes to leukocyte-mediated endothelial apoptosis in diabetes
S Chandrakumar, IS Tierno, M Agarwal, E Lessieur, H Liu, TS Kern, ...
Investigative Ophthalmology & Visual Science 63 (7), 3595–A0050-3595–A0050, 2022
12022
Partial deletion of Lrat inhibits prodromal characteristics of diabetic retinopathy
EM Lessieur, Y Du, A Saadane, H Liu, J Kiser, TS Kern
Investigative Ophthalmology & Visual Science 63 (7), 3590–A0045-3590–A0045, 2022
12022
Actin remodeling governs neutrophil activation: Implications for retinal capillary degeneration in diabetic retinopathy.
M Agarwal, S Chandrakumar, IS Tierno, EM Lessieur, TS Kern, K Ghosh
Investigative Ophthalmology & Visual Science 65 (7), 881-881, 2024
2024
Neutrophil-derived extracellular vesicles from diabetic mice promote retinal endothelial cell cytotoxicity
EM Lessieur, F Gao, Y Du, J Jiyacharoen, J Kiser, TS Kern
Investigative Ophthalmology & Visual Science 64 (8), 1844-1844, 2023
2023
Mechanical regulation of retinal vascular inflammation and degeneration in diabetic retinopathy
S Chandrakumar, IS Tierno, M Agarwal, EM Lessieur, Y Du, J Tang, ...
bioRxiv, 2022.12. 18.520943, 2022
2022
Deficiency in classical monocytes prevents superoxide, inflammation and retinal vascular lesions in diabetic mice
A Saadane, AA Veenstra, M Minns, Y Du, E Lessieur, TS Kern
Investigative Ophthalmology & Visual Science 63 (7), 949–A0418-949–A0418, 2022
2022
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