Progress in top-down proteomics and the analysis of proteoforms TK Toby, L Fornelli, NL Kelleher Annual review of analytical chemistry 9 (1), 499-519, 2016 | 614 | 2016 |
Best practices and benchmarks for intact protein analysis for top-down mass spectrometry DP Donnelly, CM Rawlins, CJ DeHart, L Fornelli, LF Schachner, Z Lin, ... Nature methods 16 (7), 587-594, 2019 | 340 | 2019 |
Principles of electron capture and transfer dissociation mass spectrometry applied to peptide and protein structure analysis KO Zhurov, L Fornelli, MD Wodrich, ÜA Laskay, YO Tsybin Chemical Society Reviews 42 (12), 5014-5030, 2013 | 235 | 2013 |
Middle-down analysis of monoclonal antibodies with electron transfer dissociation orbitrap fourier transform mass spectrometry L Fornelli, D Ayoub, K Aizikov, A Beck, YO Tsybin Analytical chemistry 86 (6), 3005-3012, 2014 | 212 | 2014 |
Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS L Fornelli, E Damoc, PM Thomas, NL Kelleher, K Aizikov, E Denisov, ... Molecular & Cellular Proteomics 11 (12), 1758-1767, 2012 | 175 | 2012 |
Structural analysis of intact monoclonal antibodies by electron transfer dissociation mass spectrometry YO Tsybin, L Fornelli, C Stoermer, M Luebeck, J Parra, S Nallet, FM Wurm, ... Analytical chemistry 83 (23), 8919-8927, 2011 | 160 | 2011 |
Top-down characterization of endogenous protein complexes with native proteomics OS Skinner, NA Haverland, L Fornelli, RD Melani, LHF Do Vale, ... Nature chemical biology 14 (1), 36-41, 2018 | 151 | 2018 |
Accurate sequence analysis of a monoclonal antibody by top-down and middle-down orbitrap mass spectrometry applying multiple ion activation techniques L Fornelli, K Srzentić, R Huguet, C Mullen, S Sharma, V Zabrouskov, ... Analytical chemistry 90 (14), 8421-8429, 2018 | 150 | 2018 |
Quantitation and identification of thousands of human proteoforms below 30 kDa KR Durbin, L Fornelli, RT Fellers, PF Doubleday, M Narita, NL Kelleher Journal of proteome research 15 (3), 976-982, 2016 | 124 | 2016 |
Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk I Ntai, L Fornelli, CJ DeHart, JE Hutton, PF Doubleday, RD LeDuc, ... Proceedings of the National Academy of Sciences 115 (16), 4140-4145, 2018 | 103 | 2018 |
Interlaboratory study for characterizing monoclonal antibodies by top-down and middle-down mass spectrometry K Srzentic, L Fornelli, YO Tsybin, JA Loo, H Seckler, JN Agar, ... Journal of the American Society for Mass Spectrometry 31 (9), 1783-1802, 2020 | 102 | 2020 |
In-spray supercharging of peptides and proteins in electrospray ionization mass spectrometry SM Miladinović, L Fornelli, Y Lu, KM Piech, HH Girault, YO Tsybin Analytical chemistry 84 (11), 4647-4651, 2012 | 99 | 2012 |
Mapping proteoforms and protein complexes from king cobra venom using both denaturing and native top-down proteomics RD Melani, OS Skinner, L Fornelli, GB Domont, PD Compton, NL Kelleher Molecular & Cellular Proteomics 15 (7), 2423-2434, 2016 | 98 | 2016 |
A comprehensive pipeline for translational top-down proteomics from a single blood draw TK Toby, L Fornelli, K Srzentić, CJ DeHart, J Levitsky, J Friedewald, ... Nature protocols 14 (1), 119-152, 2019 | 89 | 2019 |
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells RD Melani, VR Gerbasi, LC Anderson, JW Sikora, TK Toby, JE Hutton, ... Science 375 (6579), 411-418, 2022 | 88 | 2022 |
Advancing top-down analysis of the human proteome using a benchtop quadrupole-orbitrap mass spectrometer L Fornelli, KR Durbin, RT Fellers, BP Early, JB Greer, RD LeDuc, ... Journal of proteome research 16 (2), 609-618, 2017 | 87 | 2017 |
Top-down proteomics: Where we are, where we are going? L Fornelli, TK Toby, LF Schachner, PF Doubleday, K Srzentić, CJ DeHart, ... Journal of proteomics 175, 3, 2018 | 82 | 2018 |
Observation of ion coalescence in Orbitrap Fourier transform mass spectrometry MV Gorshkov, L Fornelli, YO Tsybin Rapid Communications in Mass Spectrometry 26 (15), 1711-1717, 2012 | 79 | 2012 |
An informatic framework for decoding protein complexes by top-down mass spectrometry OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ... Nature methods 13 (3), 237-240, 2016 | 78 | 2016 |
Proton transfer charge reduction enables high-throughput top-down analysis of large proteoforms R Huguet, C Mullen, K Srzentić, JB Greer, RT Fellers, V Zabrouskov, ... Analytical chemistry 91 (24), 15732-15739, 2019 | 77 | 2019 |