关注
Andy Lau
Andy Lau
King's College London, University College London, InstaDeep Ltd
在 instadeep.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Direct protein-lipid interactions shape the conformational landscape of secondary transporters
C Martens, M Shekhar, AJ Borysik, AM Lau, E Reading, E Tajkhorshid, ...
Nature communications 9 (1), 4151, 2018
1402018
Structural lipids enable the formation of functional oligomers of the eukaryotic purine symporter UapA
E Pyle, AC Kalli, S Amillis, Z Hall, AM Lau, AC Hanyaloglu, G Diallinas, ...
Cell chemical biology 25 (7), 840-848. e4, 2018
802018
Deuteros 2.0: peptide-level significance testing of data from hydrogen deuterium exchange mass spectrometry
AM Lau, J Claesen, K Hansen, A Politis
Bioinformatics 37 (2), 270-272, 2021
712021
Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry
AMC Lau, Z Ahdash, C Martens, A Politis
Bioinformatics 35 (17), 3171-3173, 2019
672019
Surface accessibility and dynamics of macromolecular assemblies probed by covalent labeling mass spectrometry and integrative modeling
C Schmidt, JA Macpherson, AM Lau, KW Tan, F Fraternali, A Politis
Analytical chemistry 89 (3), 1459-1468, 2017
642017
Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome
SV Faull, AMC Lau, C Martens, Z Ahdash, K Hansen, H Yebenes, ...
Nature communications 10 (1), 3814, 2019
582019
Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterized proteins
SM Kandathil, JG Greener, AM Lau, DT Jones
Proceedings of the National Academy of Sciences 119 (4), e2113348119, 2022
51*2022
Integrating hydrogen–deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins
C Martens, M Shekhar, AM Lau, E Tajkhorshid, A Politis
Nature protocols 14 (11), 3183-3204, 2019
512019
A mass‐spectrometry‐based modelling workflow for accurate prediction of IgG antibody conformations in the gas phase
K Hansen, AM Lau, K Giles, JM McDonnell, WB Struwe, BJ Sutton, ...
Angewandte Chemie 130 (52), 17440-17445, 2018
492018
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB
E Reading, Z Ahdash, C Fais, V Ricci, X Wang-Kan, E Grimsey, J Stone, ...
Nature communications 11 (1), 5565, 2020
472020
Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter
R Jia, C Martens, M Shekhar, S Pant, GA Pellowe, AM Lau, HE Findlay, ...
Nature communications 11 (1), 6162, 2020
402020
Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry
A Stützer, LM Welp, M Raabe, T Sachsenberg, C Kappert, A Wulf, AM Lau, ...
Nature communications 11 (1), 5250, 2020
392020
Zinc-induced oligomerization of zinc α2 glycoprotein reveals multiple fatty acid-binding sites
H Zahid, L Miah, AM Lau, L Brochard, D Hati, TTT Bui, AF Drake, J Gor, ...
Biochemical Journal 473 (1), 43-54, 2016
292016
Mechanistic insight into the assembly of the HerA–NurA helicase–nuclease DNA end resection complex
Z Ahdash, AM Lau, RT Byrne, K Lammens, A Stüetzer, H Urlaub, PJ Booth, ...
Nucleic acids research 45 (20), 12025-12038, 2017
282017
Machine learning methods for predicting protein structure from single sequences
SM Kandathil, AM Lau, DT Jones
Current Opinion in Structural Biology 81, 102627, 2023
102023
Structural predictions of the functions of membrane proteins from HDX-MS
AM Lau, R Jia, RT Bradshaw, A Politis
Biochemical Society Transactions, 2020
102020
Merizo: a rapid and accurate protein domain segmentation method using invariant point attention
AM Lau, SM Kandathil, DT Jones
Nature Communications 14 (1), 8445, 2023
7*2023
Crystal structure of zinc-α2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding
AM Lau, H Zahid, J Gor, SJ Perkins, AR Coker, LC McDermott
Biochemical Journal 476 (19), 2815-2834, 2019
72019
Analyzing protein architectures and protein-ligand complexes by integrative structural mass spectrometry
Z Ahdash, AM Lau, C Martens, A Politis
JoVE (Journal of Visualized Experiments), e57966, 2018
62018
Integrative Mass Spectrometry–Based Approaches for Modeling Macromolecular Assemblies
AM Lau, A Politis
Multiprotein Complexes: Methods and Protocols, 221-241, 2021
52021
系统目前无法执行此操作,请稍后再试。
文章 1–20