| DNA targeting specificity of RNA-guided Cas9 nucleases PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, ... Nature biotechnology 31 (9), 827-832, 2013 | 5532 | 2013 |
| CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity TJ Cradick, EJ Fine, CJ Antico, G Bao Nucleic acids research 41 (20), 9584-9592, 2013 | 799 | 2013 |
| COSMID: a web-based tool for identifying and validating CRISPR/Cas off-target sites TJ Cradick, P Qiu, CM Lee, EJ Fine, G Bao Molecular Therapy-Nucleic Acids 3, 2014 | 405 | 2014 |
| TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity C Mussolino, J Alzubi, EJ Fine, R Morbitzer, TJ Cradick, T Lahaye, G Bao, ... Nucleic acids research 42 (10), 6762-6773, 2014 | 239 | 2014 |
| Quantifying on-and off-target genome editing A Hendel, EJ Fine, G Bao, MH Porteus Trends in biotechnology 33 (2), 132-140, 2015 | 175 | 2015 |
| An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage EJ Fine, TJ Cradick, CL Zhao, Y Lin, G Bao Nucleic acids research 42 (6), e42-e42, 2014 | 157 | 2014 |
| Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing A Hendel, EJ Kildebeck, EJ Fine, JT Clark, N Punjya, V Sebastiano, ... Cell reports 7 (1), 293-305, 2014 | 146 | 2014 |
| Enhanced endothelial cell functions on rosette nanotube-coated titanium vascular stents E Fine, L Zhang, H Fenniri, TJ Webster International Journal of Nanomedicine, 91-97, 2009 | 101 | 2009 |
| CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep M Vilarino, ST Rashid, FP Suchy, BR McNabb, T Van Der Meulen, EJ Fine, ... Scientific reports 7 (1), 17472, 2017 | 96 | 2017 |
| Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes EJ Fine, CM Appleton, DE White, MT Brown, H Deshmukh, ML Kemp, ... Scientific reports 5 (1), 10777, 2015 | 74 | 2015 |
| SAPTA: a new design tool for improving TALE nuclease activity Y Lin, EJ Fine, Z Zheng, CJ Antico, RA Voit, MH Porteus, TJ Cradick, ... Nucleic acids research 42 (6), e47-e47, 2014 | 70 | 2014 |
| TALENs facilitate single-step seamless SDF correction of F508del CFTR in airway epithelial submucosal gland cell-derived CF-iPSCs S Suzuki, RG Sargent, B Illek, H Fischer, A Esmaeili-Shandiz, MJ Yezzi, ... Molecular Therapy-Nucleic Acids 5, 2016 | 49 | 2016 |
| Nanomedicine: tiny particles and machines give huge gains S Tong, EJ Fine, Y Lin, TJ Cradick, G Bao Annals of biomedical engineering 42, 243-259, 2014 | 40 | 2014 |
| Codon Swapping of Zinc Finger Nucleases Confers Expression in Primary Cells and In Vivo from a Single Lentiviral Vector C Abarrategui-Pontes, A Creneguy, R Thinard, F Eli J, V Thepenier, ... Current Gene Therapy 14 (5), 365-376, 2014 | 12 | 2014 |
| Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models EJ Fine, TJ Cradick, G Bao Gene Correction: Methods and Protocols, 371-383, 2014 | 5 | 2014 |
Gang BaoFoyt Family Professor, Bioengineering, Rice University在 rice.edu 的电子邮件经过验证
Gang BaoFoyt Family Professor, Bioengineering, Rice University在 rice.edu 的电子邮件经过验证
TJ Cradick#CRISPR Consulting https://geneeditingfrontiers.com在 alum.mit.edu 的电子邮件经过验证