Regulation of the intrinsic apoptosis pathway by reactive oxygen species CC Wu, SB Bratton Antioxidants & redox signaling 19 (6), 546-558, 2013 | 404 | 2013 |
The Apaf-1 apoptosome induces formation of caspase-9 homo-and heterodimers with distinct activities CC Wu, S Lee, S Malladi, MD Chen, NJ Mastrandrea, Z Zhang, SB Bratton Nature communications 7 (1), 13565, 2016 | 86 | 2016 |
Caspase-9 swings both ways in the apoptosome CC Wu, SB Bratton Molecular & cellular oncology 4 (2), e1281865, 2017 | 19 | 2017 |
Inactivation of ataxia telangiectasia mutated gene can increase intracellular reactive oxygen species levels and alter radiation-induced cell death pathways in human glioma cells SC Wang, CC Wu, YY Wei, JH Hong, CS Chiang International Journal of Radiation Biology 87 (4), 432-442, 2011 | 14 | 2011 |
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase KA Baltgalvis, KN Lamb, KT Symons, CC Wu, MA Hoffman, AN Snead, ... Nature, 1-8, 2024 | 6 | 2024 |
DARK apoptosome secrets come to light CC Wu, SB Bratton Structure 19 (1), 4-6, 2011 | 3 | 2011 |
SM08502, a novel, small-molecule CDC-like kinase (CLK) inhibitor, demonstrates strong antitumor effects and Wnt and cyclin D-CDK4/6-RB pathway inhibition in hormone-receptor … H Chung, L Sitts, CC Wu, B Eastman, CC Mak, S KC, J Stewart, ... Cancer Research 80 (16_Supplement), 6401-6401, 2020 | 2 | 2020 |
Abstract ND11: Chemoproteomic-enabled discovery of VVD-214, a synthetic lethal allosteric inhibitor of WRN helicase S Kikuchi, P Pettazzoni, KA Baltgalvis, KN Lamb, KT Symons, CC Wu, ... Cancer Research 84 (7_Supplement), ND11-ND11, 2024 | | 2024 |
A phase 1b/2 clinical study of onvansertib in combination with FOLFIRI/bevacizumab revealed a new role of PLK1 in regulating the hypoxia pathway in KRAS-mutant colorectal cancer M Ridinger, A Karki, RA Subramanian, E Samuelsz, D Yemane, R Kim, ... Cancer Research 84 (6_Supplement), 2031-2031, 2024 | | 2024 |
The PLK1 inhibitor, onvansertib, synergizes with paclitaxel in small cell lung cancer JC Schmitz, CC Wu, G Zhang, A Pannucci, L Hassaine, M Luebbermann, ... Survival 46 (67d), 60d, 2024 | | 2024 |
Activation of caspase-9 within the Apaf-1 apoptosome CC Wu | | 2015 |
Triple Helix-Forming Oligonucleotides Specifically Reduces ATM Transcription, Translation, and Radiosensitivity in Human Glioma Cells CC Wu, CS Chiang Molecular Therapy 15 (1_Supplement), 641-641, 2007 | | 2007 |
Different roles of p53 on ATM-mediated radiosensitivity and oxidative stress response in glioma cells. SC Wang, CC Wu, JH hong, CS Chiang Cancer Research 67 (9_Supplement), 3897-3897, 2007 | | 2007 |
探討 ATM 之基因放射療法在惡性腦癌之應用性 CC Wu 清華大學生醫工程與環境科學系學位論文 2006, 1-103, 2006 | | 2006 |