The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease Y Qian, C Liu, J Hartupee, CZ Altuntas, MF Gulen, D Jane-Wit, J Xiao, ... Nature immunology 8 (3), 247-256, 2007 | 675 | 2007 |
Complement membrane attack complex: new roles, mechanisms of action, and therapeutic targets CB Xie, D Jane-Wit, JS Pober The American journal of pathology 190 (6), 1138-1150, 2020 | 151 | 2020 |
β1-Adrenergic Receptor Autoantibodies Mediate Dilated Cardiomyopathy by Agonistically Inducing Cardiomyocyte Apoptosis D Jane-wit, CZ Altuntas, JM Johnson, S Yong, PJ Wickley, P Clark, ... Circulation 116 (4), 399-410, 2007 | 151 | 2007 |
Alloantibody and complement promote T cell–mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells D Jane-Wit, TD Manes, T Yi, L Qin, P Clark, NC Kirkiles-Smith, P Abrahimi, ... Circulation 128 (23), 2504-2516, 2013 | 138 | 2013 |
An autoimmune-mediated strategy for prophylactic breast cancer vaccination R Jaini, P Kesaraju, JM Johnson, CZ Altuntas, D Jane-Wit, VK Tuohy Nature medicine 16 (7), 799-803, 2010 | 127 | 2010 |
IL-17 promotes neutrophil-mediated immunity by activating microvascular pericytes and not endothelium R Liu, HM Lauridsen, RA Amezquita, RW Pierce, D Jane-Wit, C Fang, ... The Journal of Immunology 197 (6), 2400-2408, 2016 | 123 | 2016 |
Interacting mechanisms in the pathogenesis of cardiac allograft vasculopathy JS Pober, D Jane-Wit, L Qin, G Tellides Arteriosclerosis, thrombosis, and vascular biology 34 (8), 1609-1614, 2014 | 123 | 2014 |
Increased frequencies of cochlin-specific T cells in patients with autoimmune sensorineural hearing loss MJ Baek, HM Park, JM Johnson, CZ Altuntas, D Jane-Wit, R Jaini, ... The journal of immunology 177 (6), 4203-4210, 2006 | 116 | 2006 |
Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation J Devalliere, WG Chang, JW Andrejecsk, P Abrahimi, CJ Cheng, ... The FASEB Journal 28 (2), 908, 2014 | 88 | 2014 |
Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+NIK+ signalosome on Rab5+ endosomes D Jane-wit, YV Surovtseva, L Qin, G Li, R Liu, P Clark, TD Manes, C Wang, ... Proceedings of the National Academy of Sciences 112 (31), 9686-9691, 2015 | 72 | 2015 |
Complement membrane attack complexes assemble NLRP3 inflammasomes triggering IL-1 activation of IFN-γ–primed human endothelium CB Xie, L Qin, G Li, C Fang, NC Kirkiles-Smith, G Tellides, JS Pober, ... Circulation research 124 (12), 1747-1759, 2019 | 66 | 2019 |
Recent advances in allograft vasculopathy J Merola, DD Jane-Wit, JS Pober Current opinion in organ transplantation 22 (1), 1-7, 2017 | 60 | 2017 |
Mechanisms of dysfunction in senescent pulmonary endothelium D Jane-Wit, HJ Chun Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012 | 42 | 2012 |
Endothelial cell–derived interleukin-18 released during ischemia reperfusion injury selectively expands t peripheral helper cells to promote alloantibody production L Liu, C Fang, W Fu, B Jiang, G Li, L Qin, J Rosenbluth, G Gong, CB Xie, ... Circulation 141 (6), 464-478, 2020 | 38 | 2020 |
Coronavirus disease 2019 (COVID-19) coronary vascular thrombosis: correlation with neutrophil but not endothelial activation JE Johnson, D McGuone, ML Xu, D Jane-Wit, RN Mitchell, P Libby, ... The American Journal of Pathology 192 (1), 112-120, 2022 | 34 | 2022 |
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes C Fang, TD Manes, L Liu, K Liu, L Qin, G Li, Z Tobiasova, ... Nature communications 10 (1), 2247, 2019 | 34 | 2019 |
Variation in results from randomized, controlled trials: stochastic or systematic? D Jane-wit, RI Horwitz, J Concato Journal of clinical epidemiology 63 (1), 56-63, 2010 | 33 | 2010 |
Complement C5 inhibition reduces T cell–mediated allograft vasculopathy caused by both alloantibody and ischemia reperfusion injury in humanized mice L Qin, G Li, N Kirkiles-Smith, P Clark, C Fang, Y Wang, ZX Yu, D Devore, ... American Journal of Transplantation 16 (10), 2865-2876, 2016 | 31 | 2016 |
Complement-activated interferon-γ–primed human endothelium transpresents interleukin-15 to CD8+ T cells CB Xie, B Jiang, L Qin, G Tellides, NC Kirkiles-Smith, D Jane-Wit, ... The Journal of Clinical Investigation 130 (7), 3437-3452, 2020 | 28 | 2020 |
A novel class II-binding motif selects peptides that mediate organ-specific autoimmune disease in SWXJ, SJL/J, and SWR/J mice D Jane-wit, M Yu, AE Edling, S Kataoka, JM Johnson, LB Stull, ... The Journal of Immunology 169 (11), 6507-6514, 2002 | 27 | 2002 |