CRISPResso2 provides accurate and rapid genome editing sequence analysis K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ... Nature biotechnology 37 (3), 224-226, 2019 | 1075 | 2019 |
Highly efficient therapeutic gene editing of human hematopoietic stem cells Y Wu, J Zeng, BP Roscoe, P Liu, Q Yao, CR Lazzarotto, K Clement, ... Nature medicine 25 (5), 776-783, 2019 | 455 | 2019 |
Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS T Yamauchi, T Masuda, MC Canver, M Seiler, Y Semba, M Shboul, ... Cancer cell 33 (3), 386-400. e5, 2018 | 129 | 2018 |
Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci MC Canver, S Lessard, L Pinello, Y Wu, Y Ilboudo, EN Stern, ... Nature genetics 49 (4), 625-634, 2017 | 117 | 2017 |
Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis F Sher, M Hossain, D Seruggia, VAC Schoonenberg, Q Yao, P Cifani, ... Nature genetics 51 (7), 1149-1159, 2019 | 97 | 2019 |
ZNF410 represses fetal globin by singular control of CHD4 DS Vinjamur, Q Yao, MA Cole, C McGuckin, C Ren, J Zeng, M Hossain, ... Nature genetics 53 (5), 719-728, 2021 | 51 | 2021 |
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ... Nature methods 15 (12), 992-993, 2018 | 36 | 2018 |
Distinct nuclear compartment-associated genome architecture in the developing mammalian brain SH Ahanger, RN Delgado, E Gil, MA Cole, J Zhao, SJ Hong, ... Nature neuroscience 24 (9), 1235-1242, 2021 | 35 | 2021 |
CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis VAC Schoonenberg, MA Cole, Q Yao, C Macias-Treviño, F Sher, ... Genome biology 19, 1-19, 2018 | 32 | 2018 |
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB ED Crawford, I Acosta, V Ahyong, EC Anderson, S Arevalo, D Asarnow, ... PLoS pathogens 16 (10), e1008966, 2020 | 23 | 2020 |
Dual genome-wide coding and lncRNA screens in neural induction of induced pluripotent stem cells D Wu, A Poddar, E Ninou, E Hwang, MA Cole, SJ Liu, MA Horlbeck, ... Cell genomics 2 (11), 2022 | 15 | 2022 |
Accurate and rapid analysis of genome editing data from nucleases and base editors with CRISPResso2 K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ... Nature biotechnology 37 (3), 224, 2019 | 11 | 2019 |
Analysis and comparison of genome editing using CRISPResso2 K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, M Cole, ... bioRxiv, 392217, 2018 | 7 | 2018 |
Genome-wide CRISPR screen identifies PAICS, an enzyme involved in de novo purine synthesis, as a potential target for AML therapy T Yamauchi, K Miyawaki, Y Semba, F Nakao, T Sugio, K Sasaki, ... Clinical Lymphoma, Myeloma and Leukemia 19, S216-S217, 2019 | 2 | 2019 |
Highly Efficient Therapeutic Gene Editing of BCL11A enhancer in Human Hematopoietic Stem Cells from ss-Hemoglobinopathy Patients for Fetal Hemoglobin Induction J Zeng, DE Bauer, Y Wu, BP Roscoe, P Liu, Q Yao, C Lazzarrotto, ... Blood 132, 3482, 2018 | 2 | 2018 |
Rational Targeting of a NuRD Sub-Complex for Fetal Hemoglobin Induction Following Comprehensive in Situ Mutagenesis M Hossain, F Sher, D Seruggia, V Schoonenberg, MA Cole, P Cifani, ... Blood 132, 2342, 2018 | 1 | 2018 |
CRISPRO Identifies Functional Protein Coding Sequences Based on Genome Editing Dense Mutagenesis VAC Schoonenberg, MA Cole, Q Yao, C Macias-Treviño, F Sher, ... bioRxiv, 326504, 2018 | 1 | 2018 |
Genome-Wide CRISPR/Cas9 Screen Reveals That the Dcps Scavenger Decapping Enzyme Is Essential for AML Cell Survival T Yamauchi, T Masuda, MC Canver, M Seiler, M Shboul, M Maeda, ... Blood 130, 782, 2017 | 1 | 2017 |
High-resolution CRISPR functional genomics reveals critical vulnerabilities of the NuRD complex for fetal hemoglobin control F Sher, V Schoonenberg, MA Cole, C Macias-Trevino, P Cifani, ... Blood 130, 286, 2017 | 1 | 2017 |
Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis SH Ahanger, C Zhang, ER Semenza, E Gil, MA Cole, L Wang, ... bioRxiv, 2024.08. 01.606248, 2024 | | 2024 |