TIA‐1 is a translational silencer that selectively regulates the expression of TNF‐α M Piecyk, S Wax, ARP Beck, N Kedersha, M Gupta, B Maritim, S Chen, ... The EMBO journal, 2000 | 606 | 2000 |
Translational blockade imposed by cytokine-derived UA-rich sequences V Kruys, O Marinx, G Shaw, J Deschamps, G Huez Science 245 (4920), 852-855, 1989 | 430 | 1989 |
Transcriptome-wide distribution and function of RNA hydroxymethylcytosine B Delatte, F Wang, LV Ngoc, E Collignon, E Bonvin, R Deplus, E Calonne, ... Science 351 (6270), 282-285, 2016 | 403 | 2016 |
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner F Van Gool, M Galli, C Gueydan, V Kruys, PP Prevot, A Bedalov, ... Nature medicine 15 (2), 206-210, 2009 | 332 | 2009 |
Tumor necrosis factor: the molecules and their emerging role in medicine B Beutler, J Han, V Kruys, B Giroir Coordinate regulation of TNF biosynthesis at the levels of transcription and …, 1992 | 328 | 1992 |
Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor α mRNA C Gueydan, L Droogmans, P Chalon, G Huez, D Caput, V Kruys Journal of Biological Chemistry 274 (4), 2322-2326, 1999 | 314 | 1999 |
The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor F De Leeuw, T Zhang, C Wauquier, G Huez, V Kruys, C Gueydan Experimental cell research 313 (20), 4130-4144, 2007 | 303 | 2007 |
B cell growth modulating and differentiating activity of recombinant human 26‐kd protein (BSF‐2, HuIFN‐beta 2, HPGF). P Poupart, P Vandenabeele, S Cayphas, J Van Snick, G Haegeman, ... The EMBO journal 6 (5), 1219-1224, 1987 | 283 | 1987 |
AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factors T Zhang, V Kruys, G Huez, C Gueydan Biochemical society transactions 30 (6), 952-958, 2002 | 276 | 2002 |
The 3'untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation. V Kruys, M Wathelet, P Poupart, R Contreras, W Fiers, J Content, G Huez Proceedings of the National Academy of Sciences 84 (17), 6030-6034, 1987 | 220 | 1987 |
Shuttling SR proteins: more than splicing factors L Twyffels, C Gueydan, V Kruys The FEBS journal 278 (18), 3246-3255, 2011 | 191 | 2011 |
The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man E Marion, PJ Kaisaki, V Pouillon, C Gueydan, JC Levy, A Bodson, ... Diabetes 51 (7), 2012-2017, 2002 | 157 | 2002 |
Interleukin-4 and-13 inhibit tumor necrosis factor-α mRNA translational activation in lipopolysaccharide-induced mouse macrophages T Mijatovic, V Kruys, D Caput, P Defrance, G Huez Journal of biological chemistry 272 (22), 14394-14398, 1997 | 153 | 1997 |
Lipopolysaccharide signal transduction, regulation of tumor necrosis factor biosynthesis, and signaling by tumor necrosis factor itself B Beutler, V Kruys Journal of cardiovascular pharmacology 25, S1-S8, 1995 | 133 | 1995 |
Tumor necrosis factor-alpha production induced by viruses and by lipopolysaccharides in macrophages: similarities and differences. V Willeaume, V Kruys, T Mijatovic, G Huez Journal of inflammation 46 (1), 1-12, 1995 | 131 | 1995 |
Transportin-1 and Transportin-2: protein nuclear import and beyond L Twyffels, C Gueydan, V Kruys FEBS letters 588 (10), 1857-1868, 2014 | 130 | 2014 |
PARP12, an interferon-stimulated gene involved in the control of protein translation and inflammation I Welsby, D Hutin, C Gueydan, V Kruys, A Rongvaux, O Leo Journal of Biological Chemistry 289 (38), 26642-26657, 2014 | 126 | 2014 |
Identification of the sequence determinants mediating the nucleo-cytoplasmic shuttling of TIAR and TIA-1 RNA-binding proteins T Zhang, N Delestienne, G Huez, V Kruys, C Gueydan Journal of cell science 118 (23), 5453-5463, 2005 | 101 | 2005 |
Constitutive activity of the tumor necrosis factor promoter is canceled by the 3'untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this … V Kruys, K Kemmer, A Shakhov, V Jongeneel, B Beutler Proceedings of the National Academy of Sciences 89 (2), 673-677, 1992 | 92 | 1992 |
Anoctamin-1/TMEM16A is the major apical iodide channel of the thyrocyte L Twyffels, A Strickaert, M Virreira, C Massart, J Van Sande, C Wauquier, ... American Journal of Physiology-Cell Physiology 307 (12), C1102-C1112, 2014 | 82 | 2014 |