Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration V Cipriani, L Lorés-Motta, F He, D Fathalla, V Tilakaratna, S McHarg, ... Nature Communications 11 (1), 778, 2020 | 93 | 2020 |
Active eosinophils regulate host defence and immune responses in colitis A Gurtner, C Borrelli, I Gonzalez-Perez, K Bach, IE Acar, NG Núñez, ... Nature 615 (7950), 151-157, 2023 | 79 | 2023 |
Integrating metabolomics, genomics, and disease pathways in age-related macular degeneration: the EYE-RISK consortium IE Acar, L Lores-Motta, JM Colijn, MA Meester-Smoor, T Verzijden, ... Ophthalmology 127 (12), 1693-1709, 2020 | 65 | 2020 |
Development of a genotype assay for age-related macular degeneration: the EYE-RISK Consortium A de Breuk, IE Acar, E Kersten, MM Schijvenaars, JM Colijn, ... Ophthalmology 128 (11), 1604-1617, 2021 | 58 | 2021 |
MicroRNA categorization using sequence motifs and k-mers M Yousef, W Khalifa, İE Acar, J Allmer BMC bioinformatics 18, 1-9, 2017 | 35 | 2017 |
Genetic risk score has added value over initial clinical grading stage in predicting disease progression in age-related macular degeneration TJ Heesterbeek, EK de Jong, IE Acar, JMM Groenewoud, B Liefers, ... Scientific Reports 9 (1), 6611, 2019 | 29 | 2019 |
Family-based exome sequencing identifies rare coding variants in age-related macular degeneration R Ratnapriya, İE Acar, MJ Geerlings, K Branham, A Kwong, NTM Saksens, ... Human molecular genetics 29 (12), 2022-2034, 2020 | 28 | 2020 |
Human memory B cells show plasticity and adopt multiple fates upon recall response to SARS-CoV-2 Y Zurbuchen, J Michler, P Taeschler, S Adamo, C Cervia, ME Raeber, ... Nature immunology 24 (6), 955-965, 2023 | 17 | 2023 |
The Expressed MicroRNA—mRNA Interactions of Toxoplasma gondii IE Acar, MD Saçar Demirci, U Groß, J Allmer Frontiers in microbiology 8, 2630, 2018 | 13 | 2018 |
Pregnancy-responsive pools of adult neural stem cells for transient neurogenesis in mothers Z Chaker, C Segalada, JA Kretz, IE Acar, AC Delgado, V Crotet, AE Moor, ... Science 382 (6673), 958-963, 2023 | 12 | 2023 |
Genome-wide characterization of circulating metabolic biomarkers MK Karjalainen, S Karthikeyan, C Oliver-Williams, E Sliz, E Allara, ... Nature 628 (8006), 130-138, 2024 | 11 | 2024 |
Distinguishing between MicroRNA targets from diverse species using sequence motifs and K-mers M Yousef, W Khalifa, İE Acar, J Allmer International Conference on Bioinformatics Models, Methods and Algorithms 4 …, 2017 | 11 | 2017 |
Semi-quantitative multiplex profiling of the complement system identifies associations of complement proteins with genetic variants and metabolites in age-related macular … IE Acar, E Willems, E Kersten, J Keizer-Garritsen, E Kragt, B Bakker, ... Journal of Personalized Medicine 11 (12), 1256, 2021 | 7 | 2021 |
Fragment-sequencing unveils local tissue microenvironments at single-cell resolution K Handler, K Bach, C Borrelli, S Piscuoglio, X Ficht, IE Acar, AE Moor Nature Communications 14 (1), 7775, 2023 | 5 | 2023 |
Genome-wide characterization of circulating metabolic biomarkers reveals substantial pleiotropy and novel disease pathways MK Karjalainen, S Karthikeyan, C Oliver-Williams, E Sliz, E Allara, ... medRxiv, 2022.10. 20.22281089, 2022 | 5 | 2022 |
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration. Nat Commun 11: 778 V Cipriani, L Lorés-Motta, F He, D Fathalla, V Tilakaratna, S McHarg, ... | 5 | 2020 |
Sphere-sequencing unveils local tissue microenvironments at single cell resolution K Handler, K Bach, C Borrelli, X Ficht, IE Acar, AE Moor bioRxiv, 2022.10. 31.514509, 2022 | 3 | 2022 |
Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration IE Acar, TE Galesloot, UFO Luhmann, S Fauser, J Gayán, ... Investigative ophthalmology & visual science 64 (14), 24-24, 2023 | 2 | 2023 |
Systemic metabolomics in a framework of genetics and lifestyle in age-related macular degeneration EF Thee, İE Acar, JM Colijn, MA Meester-Smoor, T Verzijden, SJ Baart, ... Metabolites 13 (6), 701, 2023 | 2 | 2023 |
Factor H-Related Protein 4 (FHR-4) drives complement dysregulation in age-related macular degeneration V Cipriani, LL de Motta, F He, D Fathalla, S McHarg, N Bayatti, IE Acar, ... Investigative Ophthalmology & Visual Science 60 (9), 3870-3870, 2019 | 2 | 2019 |