Elimination of protein aggregates prevents premature senescence in human trisomy 21 fibroblasts N Nawa, K Hirata, K Kawatani, T Nambara, S Omori, K Banno, C Kokubu, ... PLoS One 14 (7), e0219592, 2019 | 21 | 2019 |
A human isogenic iPSC-derived cell line panel identifies major regulators of aberrant astrocyte proliferation in Down syndrome K Kawatani, T Nambara, N Nawa, H Yoshimatsu, H Kusakabe, K Hirata, ... Communications Biology 4 (1), 730, 2021 | 20 | 2021 |
4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates K Hirata, T Nambara, K Kawatani, N Nawa, H Yoshimatsu, H Kusakabe, ... Scientific reports 10 (1), 14047, 2020 | 18 | 2020 |
A pair of maternal chromosomes derived from meiotic nondisjunction in trisomy 21 affects nuclear architecture and transcriptional regulation S Omori, H Tanabe, K Banno, A Tsuji, N Nawa, K Hirata, K Kawatani, ... Scientific Reports 7 (1), 764, 2017 | 16 | 2017 |
ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism K Kawatani, ML Holm, SC Starling, YA Martens, J Zhao, W Lu, Y Ren, Z Li, ... Molecular psychiatry 29 (3), 809-819, 2024 | 14 | 2024 |
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4 H Oue, Y Yamazaki, W Qiao, C Yuanxin, Y Ren, A Kurti, F Shue, ... JCI insight 8 (7), 2023 | 6 | 2023 |
Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 cells using a chromosome elimination technique S Wakita, M Hara, Y Kitabatake, K Kawatani, H Kurahashi, R Hashizume Journal of human genetics 67 (10), 565-572, 2022 | 3 | 2022 |