| Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ... Nature genetics 49 (12), 1779-1784, 2017 | 1624 | 2017 |
| Spiroindolones, a potent compound class for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... science 329 (5996), 1175-1180, 2010 | 1259 | 2010 |
| Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ... Science 334 (6061), 1372-1377, 2011 | 374 | 2011 |
| Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families SER Bopp, MJ Manary, AT Bright, GL Johnston, NV Dharia, FL Luna, ... PLoS genetics 9 (2), e1003293, 2013 | 247 | 2013 |
| Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ... Nature genetics 50 (9), 1240-1246, 2018 | 239 | 2018 |
| Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum NV Dharia, ABS Sidhu, MB Cassera, SJ Westenberger, SER Bopp, ... Genome biology 10, 1-13, 2009 | 165 | 2009 |
| Piperaquine Resistance Is Associated with a Copy Number Variation on Chromosome 5 in Drug-Pressured Plasmodium falciparum Parasites RT Eastman, NV Dharia, EA Winzeler, DA Fidock Antimicrobial agents and chemotherapy 55 (8), 3908-3916, 2011 | 164 | 2011 |
| Validation of isoleucine utilization targets in Plasmodium falciparum ES Istvan, NV Dharia, SE Bopp, I Gluzman, EA Winzeler, DE Goldberg Proceedings of the National Academy of Sciences 108 (4), 1627-1632, 2011 | 151 | 2011 |
| EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma AB Iniguez, B Stolte, EJ Wang, AS Conway, G Alexe, NV Dharia, ... Cancer cell 33 (2), 202-216. e6, 2018 | 149 | 2018 |
| CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2 L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ... The Journal of clinical investigation 128 (1), 446-462, 2018 | 144 | 2018 |
| A Systems-Based Analysis of Plasmodium vivax Lifecycle Transcription from Human to Mosquito SJ Westenberger, CM McClean, R Chattopadhyay, NV Dharia, JM Carlton, ... PLoS neglected tropical diseases 4 (4), e653, 2010 | 133 | 2010 |
| Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes NV Dharia, AT Bright, SJ Westenberger, SW Barnes, S Batalov, K Kuhen, ... Proceedings of the National Academy of Sciences 107 (46), 20045-20050, 2010 | 127 | 2010 |
| A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor T Nam, CW McNamara, S Bopp, NV Dharia, S Meister, GMC Bonamy, ... ACS chemical biology 6 (11), 1214-1222, 2011 | 107 | 2011 |
| A first-generation pediatric cancer dependency map NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ... Nature genetics 53 (4), 529-538, 2021 | 103 | 2021 |
| Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core … SJ Westenberger, L Cui, N Dharia, E Winzeler, L Cui BMC genomics 10, 1-17, 2009 | 97 | 2009 |
| Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia Y Gocho, J Liu, J Hu, W Yang, NV Dharia, J Zhang, H Shi, G Du, A John, ... Nature cancer 2 (3), 284-299, 2021 | 96 | 2021 |
| Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ... Nature communications 9 (1), 2024, 2018 | 95 | 2018 |
| EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma AD Durbin, T Wang, VK Wimalasena, MW Zimmerman, D Li, NV Dharia, ... Cancer discovery 12 (3), 730-751, 2022 | 89 | 2022 |
| Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation A Sacher, P LoRusso, MR Patel, WH Miller Jr, E Garralda, MD Forster, ... New England Journal of Medicine 389 (8), 710-721, 2023 | 83 | 2023 |
| A combination CDK4/6 and IGF1R inhibitor strategy for Ewing sarcoma LM Guenther, NV Dharia, L Ross, A Conway, AL Robichaud, JL Catlett, ... Clinical Cancer Research 25 (4), 1343-1357, 2019 | 80 | 2019 |
