Estrogen, neuroinflammation and neuroprotection in Parkinson’s disease: glia dictates resistance versus vulnerability to neurodegeneration MC Morale, PA Serra, F L’Episcopo, C Tirolo, S Caniglia, N Testa, ... Neuroscience 138 (3), 869-878, 2006 | 251 | 2006 |
microRNAs in Parkinson’s disease: from pathogenesis to novel diagnostic and therapeutic approaches L Leggio, S Vivarelli, F L’Episcopo, C Tirolo, S Caniglia, N Testa, ... International journal of molecular sciences 18 (12), 2698, 2017 | 232 | 2017 |
Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine model of Parkinson's disease F L'Episcopo, C Tirolo, N Testa, S Caniglia, MC Morale, C Cossetti, ... Neurobiology of disease 41 (2), 508-527, 2011 | 204 | 2011 |
A Wnt1 regulated Frizzled-1/β-Cateninsignaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk … F L'episcopo, MF Serapide, C Tirolo, N Testa, S Caniglia, MC Morale, ... Molecular neurodegeneration 6, 1-29, 2011 | 199 | 2011 |
Bilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (Mrp1) F Gennuso, C Fernetti, C Tirolo, N Testa, F L'Episcopo, S Caniglia, ... Proceedings of the National Academy of Sciences 101 (8), 2470-2475, 2004 | 189 | 2004 |
Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between … F L'Episcopo, C Tirolo, N Testa, S Caniglia, MC Morale, M Deleidi, ... Journal of Neuroscience 32 (6), 2062-2085, 2012 | 148 | 2012 |
Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair B Marchetti, C Tirolo, F L'Episcopo, S Caniglia, N Testa, JA Smith, ... Aging cell 19 (3), e13101, 2020 | 130 | 2020 |
Wnt/β-catenin signaling is required to rescue midbrain dopaminergic progenitors and promote neurorepair in ageing mouse model of Parkinson’s disease F L’Episcopo, C Tirolo, N Testa, S Caniglia, MC Morale, MF Serapide, ... Stem Cells 32 (8), 2147-2163, 2014 | 112 | 2014 |
Aging-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation F L'Episcopo, C Tirolo, N Testa, S Caniglia, MC Morale, F Impagnatiello, ... Journal of Neuroscience 33 (4), 1462-1485, 2013 | 101 | 2013 |
Uncovering novel actors in astrocyte–neuron crosstalk in P arkinson's disease: the W nt/β‐catenin signaling cascade as the common final pathway for neuroprotection and self‐repair B Marchetti, F L'Episcopo, MC Morale, C Tirolo, N Testa, S Caniglia, ... European Journal of Neuroscience 37 (10), 1550-1563, 2013 | 95 | 2013 |
Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease F L'Episcopo, C Tirolo, S Caniglia, N Testa, MC Morale, MF Serapide, ... Journal of molecular cell biology 6 (1), 13-26, 2014 | 87 | 2014 |
Glucocorticoid receptor deficiency increases vulnerability of the nigrostriatal dopaminergic system: critical role of glial nitric oxide MC Morale, PA Serra, MR Delogu, R Migheli, G Rocchitta, C Tirolo, ... The FASEB journal 18 (1), 164-166, 2004 | 83 | 2004 |
GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington’s disease: involvement of astrocyte–neuron interactions F L'episcopo, J Drouin-Ouellet, C Tirolo, A Pulvirenti, R Giugno, N Testa, ... Cell death & disease 7 (4), e2206-e2206, 2016 | 80 | 2016 |
Microglia polarization, gene-environment interactions and Wnt/β-catenin signaling: emerging roles of glia-neuron and glia-stem/neuroprogenitor crosstalk for dopaminergic … F L'Episcopo, C Tirolo, MF Serapide, S Caniglia, N Testa, L Leggio, ... Frontiers in aging neuroscience 10, 12, 2018 | 78 | 2018 |
Glucocorticoid receptor–nitric oxide crosstalk and vulnerability to experimental Parkinsonism: pivotal role for glia–neuron interactions B Marchetti, PA Serra, C Tirolo, F L'episcopo, S Caniglia, F Gennuso, ... Brain Research Reviews 48 (2), 302-321, 2005 | 77 | 2005 |
Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1, 2, 3, 6 … F L'Episcopo, C Tirolo, S Caniglia, N Testa, PA Serra, F Impagnatiello, ... Journal of neuroinflammation 7, 1-21, 2010 | 75 | 2010 |
Glia as a turning point in the therapeutic strategy of Parkinson's disease F L'Episcopo, C Tirolo, N Testa, S Caniglia, M Concetta Morale, ... CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010 | 73 | 2010 |
Reactive astrocytes are key players in nigrostriatal dopaminergic neurorepair in the MPTP mouse model of Parkinson’s disease: focus on endogenous neurorestoration F L’Episcopo, C Tirolo, N Testa, S Caniglia, M Concetta Morale, ... Current aging science 6 (1), 45-55, 2013 | 66 | 2013 |
Loss of aromatase cytochrome P450 function as a risk factor for Parkinson's disease? MC Morale, F L'Episcopo, C Tirolo, G Giaquinta, S Caniglia, N Testa, ... Brain research reviews 57 (2), 431-443, 2008 | 64 | 2008 |
Neural stem cell grafts promote astroglia-driven neurorestoration in the aged parkinsonian brain via Wnt/β-catenin signaling F L'episcopo, C Tirolo, L Peruzzotti-Jametti, MF Serapide, N Testa, ... Stem Cells 36 (8), 1179-1197, 2018 | 56 | 2018 |