MEMBPLUGIN: studying membrane complexity in VMD R Guixà-González, I Rodriguez-Espigares, JM Ramírez-Anguita, ... Bioinformatics 30 (10), 1478-1480, 2014 | 256 | 2014 |
Membrane cholesterol access into a G-protein-coupled receptor R Guixà-González, JL Albasanz, I Rodriguez-Espigares, M Pastor, F Sanz, ... Nature Communications 8, 14505, 2017 | 155 | 2017 |
Structural insights into the process of GPCR-G protein complex formation X Liu, X Xu, D Hilger, P Aschauer, JKS Tiemann, Y Du, H Liu, K Hirata, ... Cell 177 (5), 1243-1251. e12, 2019 | 147 | 2019 |
GPCRmd uncovers the dynamics of the 3D-GPCRome I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ... Nature Methods 17 (8), 777-787, 2020 | 118 | 2020 |
Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors R Guixà-González, M Javanainen, M Gómez-Soler, B Cordobilla, ... Scientific Reports 6, 19839, 2016 | 116 | 2016 |
Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain G Beliu, S Altrichter, R Guixà-González, M Hemberger, I Brauer, ... Molecular Cell 81 (5), 905-921. e5, 2021 | 67 | 2021 |
Control of glutamate release by complexes of adenosine and cannabinoid receptors A Köfalvi, E Moreno, A Cordomí, NS Cai, V Fernández-Dueñas, ... BMC biology 18, 1-21, 2020 | 66 | 2020 |
Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms E Ghosh, H Dwivedi, M Baidya, A Srivastava, P Kumari, T Stepniewski, ... Cell Reports 28 (13), 3287-3299. e6, 2019 | 61 | 2019 |
Ultrafast structural changes direct the first molecular events of vision T Gruhl, T Weinert, MJ Rodrigues, CJ Milne, G Ortolani, K Nass, E Nango, ... Nature 615 (7954), 939-944, 2023 | 54 | 2023 |
Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist P Isaikina, CJ Tsai, N Dietz, F Pamula, A Grahl, KN Goldie, ... Science Advances 7 (25), eabg8685, 2021 | 52 | 2021 |
MDsrv: viewing and sharing molecular dynamics simulations on the web JKS Tiemann, R Guixà-González, PW Hildebrand, AS Rose Nature Methods 14 (12), 1123, 2017 | 39 | 2017 |
Molecular Modeling and Simulation of Membrane Lipid-Mediated Effects on GPCRs SK Sadiq, R Guixà-González, E Dainese, M Pastor, G De Fabritiis, ... Current Medicinal Chemistry 20 (1), 22-38, 2013 | 39 | 2013 |
Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design M Marti-Solano, R Guixa-Gonzalez, F Sanz, M Pastor, J Selent Current pharmaceutical design 19 (28), 5156-5166, 2013 | 35 | 2013 |
The antioxidant resveratrol acts as a non-selective adenosine receptor agonist A Sánchez-Melgar, JL Albasanz, R Guixà-González, N Saleh, J Selent, ... Free Radical Biology and Medicine 135, 261-273, 2019 | 30 | 2019 |
Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions M Javanainen, G Enkavi, R Guixà-Gonzaléz, W Kulig, H Martinez-Seara, ... PLOS Computational Biology 15 (5), e1007033, 2019 | 28 | 2019 |
HomolWat: a web server tool to incorporate ‘homologous’ water molecules into GPCR structures E Mayol, A García-Recio, JKS Tiemann, PW Hildebrand, ... Nucleic acids research 48 (W1), W54-W59, 2020 | 23 | 2020 |
SCoV2-MD: a database for the dynamics of the SARS-CoV-2 proteome and variant impact predictions M Torrens-Fontanals, A Peralta-García, C Talarico, R Guixà-González, ... Nucleic acids research 50 (D1), D858-D866, 2022 | 22 | 2022 |
Computational strategies to incorporate GPCR complexity in drug design M Martí-Solano, AA Kaczor, R Guixà-González, J Selent Frontiers in Computational Chemistry 1, 2015 | 22* | 2015 |
Fractal dimension as a measure of surface roughness of G protein-coupled receptors: implications for structure and function AA Kaczor, R Guixà-González, P Carrió, C Obiol-Pardo, M Pastor, ... Journal of Molecular Modeling, 1-11, 2012 | 22 | 2012 |
Crosstalk within GPCR Heteromers in Schizophrenia and Parkinsons Disease: Physical or Just Functional? R Guixà-González, A Bruno, M Marti-Solano, J Selent Current Medicinal Chemistry 19 (8), 1119-1134, 2012 | 19 | 2012 |