Harnessing 64Cu/67Cu for a theranostic approach to pretargeted radioimmunotherapy O Keinänen, K Fung, JM Brennan, N Zia, M Harris, E van Dam, C Biggin, ... Proceedings of the National Academy of Sciences 117 (45), 28316-28327, 2020 | 93 | 2020 |
Pretargeting of internalizing trastuzumab and cetuximab with a 18F-tetrazine tracer in xenograft models O Keinänen, K Fung, J Pourat, V Jallinoja, D Vivier, NVK Pillarsetty, ... EJNMMI research 7, 1-12, 2017 | 76 | 2017 |
A new highly reactive and low lipophilicity fluorine-18 labeled tetrazine derivative for pretargeted PET imaging O Keinanen, XG Li, NK Chenna, D Lumen, J Ott, CFM Molthoff, ... Acs medicinal chemistry letters 7 (1), 62-66, 2016 | 66 | 2016 |
Pretargeted PET Imaging of trans-Cyclooctene-Modified Porous Silicon Nanoparticles O Keinänen, EM Mäkilä, R Lindgren, H Virtanen, H Liljenbäck, ... ACS omega 2 (1), 62-69, 2017 | 56 | 2017 |
Synthesis, in vitro and in vivo evaluation of 1, 3, 5-triazines as cannabinoid CB2 receptor agonists S Yrjölä, M Sarparanta, AJ Airaksinen, M Hytti, A Kauppinen, ... European Journal of Pharmaceutical Sciences 67, 85-96, 2015 | 46 | 2015 |
Radiolabeled molecular imaging probes for the in vivo evaluation of cellulose nanocrystals for biomedical applications S Imlimthan, S Otaru, O Keinanen, A Correia, K Lintinen, HA Santos, ... Biomacromolecules 20 (2), 674-683, 2018 | 44 | 2018 |
Dual radionuclide theranostic pretargeting O Keinänen, JM Brennan, R Membreno, K Fung, K Gangangari, ... Molecular pharmaceutics 16 (10), 4416-4421, 2019 | 38 | 2019 |
Harnessing PET to track micro-and nanoplastics in vivo O Keinänen, EJ Dayts, C Rodriguez, SM Sarrett, JM Brennan, ... Scientific Reports 11 (1), 11463, 2021 | 34 | 2021 |
A theranostic cellulose nanocrystal‐based drug delivery system with enhanced retention in pulmonary metastasis of melanoma S Imlimthan, YC Khng, O Keinänen, W Zhang, AJ Airaksinen, ... Small 17 (18), 2007705, 2021 | 33 | 2021 |
Toward the optimization of click-mediated pretargeted radioimmunotherapy R Membreno, OM Keinänen, BE Cook, KM Tully, KC Fung, JS Lewis, ... Molecular pharmaceutics 16 (5), 2259-2263, 2019 | 29 | 2019 |
Inverse electron demand Diels–Alder click chemistry for pretargeted PET imaging and radioimmunotherapy SM Sarrett, O Keinänen, EJ Dayts, G Dewaele-Le Roi, C Rodriguez, ... Nature protocols 16 (7), 3348-3381, 2021 | 27 | 2021 |
ImmunoPET of ovarian and pancreatic cancer with AR9. 6, a novel MUC16-targeted therapeutic antibody SK Sharma, KN Mack, A Piersigilli, J Pourat, KJ Edwards, O Keinänen, ... Clinical Cancer Research 28 (5), 948-959, 2022 | 23 | 2022 |
A molecularly targeted intraoperative near-infrared fluorescence imaging agent for high-grade serous ovarian cancer K Fung, SK Sharma, O Keinänen, KL Roche, JS Lewis, BM Zeglis Molecular pharmaceutics 17 (8), 3140-3147, 2020 | 18 | 2020 |
Antibody engineering for nuclear imaging and radioimmunotherapy C Rodriguez, S Delaney, SM Sarrett, OM Keinänen, BM Zeglis Journal of Nuclear Medicine 63 (9), 1316-1322, 2022 | 12 | 2022 |
Efficient cartridge purification for producing high molar activity [18F] fluoro-glycoconjugates via oxime formation O Keinänen, D Partelová, O Alanen, M Antopolsky, M Sarparanta, ... Nuclear medicine and biology 67, 27-35, 2018 | 11 | 2018 |
Synthesis and Comparative In Vivo Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET SK Sharma, P Adumeau, O Keinanen, V Sisodiya, H Sarvaiya, R Tchelepi, ... Bioconjugate chemistry 32 (7), 1255-1262, 2021 | 10 | 2021 |
CD133 as a biomarker for an autoantibody-to-ImmunoPET paradigm for the early detection of small cell Lung Cancer AG Kunihiro, SM Sarrett, KJ Lastwika, JL Solan, T Pisarenko, O Keinänen, ... Journal of Nuclear Medicine 63 (11), 1701-1707, 2022 | 9 | 2022 |
Lysine-directed site-selective bioconjugation for the creation of radioimmunoconjugates SM Sarrett, C Rodriguez, G Rymarczyk, MM Hosny, O Keinanen, ... Bioconjugate chemistry 33 (9), 1750-1760, 2022 | 9 | 2022 |
89Zr-Labeled AR20.5: A MUC1-Targeting ImmunoPET Probe K Fung, D Vivier, O Keinänen, EK Sarbisheh, EW Price, BM Zeglis Molecules 25 (10), 2315, 2020 | 9 | 2020 |
Unraveling the in vivo fate of inhaled micro-and nanoplastics with PET imaging S Delaney, C Rodriguez, SM Sarrett, EJ Dayts, BM Zeglis, O Keinänen Science of the Total Environment 904, 166320, 2023 | 7 | 2023 |