Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity EP Cummins, E Berra, KM Comerford, A Ginouves, KT Fitzgerald, ... Proceedings of the National Academy of Sciences 103 (48), 18154-18159, 2006 | 918 | 2006 |
The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling M Carty, R Goodbody, M Schröder, J Stack, PN Moynagh, AG Bowie Nature immunology 7 (10), 1074-1081, 2006 | 707 | 2006 |
The NF-κB pathway PN Moynagh Journal of cell science 118 (20), 4589-4592, 2005 | 672 | 2005 |
TLR signalling and activation of IRFs: revisiting old friends from the NF-κB pathway PN Moynagh Trends in immunology 26 (9), 469-476, 2005 | 461 | 2005 |
Regulatory T cells promote myelin regeneration in the central nervous system Y Dombrowski, T O'hagan, M Dittmer, R Penalva, SR Mayoral, ... Nature neuroscience 20 (5), 674-680, 2017 | 415 | 2017 |
RIP kinases: key decision makers in cell death and innate immunity F Humphries, S Yang, B Wang, PN Moynagh Cell Death & Differentiation 22 (2), 225-236, 2015 | 273 | 2015 |
Dissection of tumor-necrosis factor-α inhibition of long-term potentiation (LTP) reveals a p38 mitogen-activated protein kinase-dependent mechanism which maps to early—but not … MP Butler, JJ O'connor, PN Moynagh Neuroscience 124 (2), 319-326, 2004 | 271 | 2004 |
Lipid peroxidation is involved in the activation of NF-κB by tumor necrosis factor but not interleukin-1 in the human endothelial cell line ECV304: lack of involvement of H2O2 … AG Bowie, PN Moynagh, LAJ O'Neill Journal of Biological Chemistry 272 (41), 25941-25950, 1997 | 225 | 1997 |
The interleukin‐1 signalling pathway in astrocytes: a key contributor to inflammation in the brain PN Moynagh Journal of anatomy 207 (3), 265-269, 2005 | 196 | 2005 |
Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis AE Hogan, AM Tobin, T Ahern, MA Corrigan, G Gaoatswe, R Jackson, ... Diabetologia 54, 2745-2754, 2011 | 181 | 2011 |
Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse ST Anderson, S Commins, PN Moynagh, AN Coogan Brain, behavior, and immunity 43, 98-109, 2015 | 171 | 2015 |
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling M van Gent, SGE Braem, A de Jong, N Delagic, JGC Peeters, IGJ Boer, ... PLoS pathogens 10 (2), e1003960, 2014 | 159 | 2014 |
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling PN Moynagh Trends in immunology 30 (1), 33-42, 2009 | 153 | 2009 |
The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome F Humphries, R Bergin, R Jackson, N Delagic, B Wang, S Yang, ... Nature communications 9 (1), 1560, 2018 | 150 | 2018 |
NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1 SM Miggin, E Pålsson-McDermott, A Dunne, C Jefferies, E Pinteaux, ... Proceedings of the National Academy of Sciences 104 (9), 3372-3377, 2007 | 148 | 2007 |
Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis S Li, Y Wu, D Yang, C Wu, C Ma, X Liu, PN Moynagh, B Wang, G Hu, ... Journal of Experimental Medicine 216 (11), 2562-2581, 2019 | 132 | 2019 |
Activation of NF-kappa B and induction of vascular cell adhesion molecule-1 and intracellular adhesion molecule-1 expression in human glial cells by IL-1. Modulation by … PN Moynagh, DC Williams, LA O'neill Journal of immunology (Baltimore, Md.: 1950) 153 (6), 2681-2690, 1994 | 132 | 1994 |
The pro-inflammatory cytokine TNF-α regulates the activity and expression of the serotonin transporter (SERT) in astrocytes S Malynn, A Campos-Torres, P Moynagh, J Haase Neurochemical research 38, 694-704, 2013 | 129 | 2013 |
The roles of Pellino E3 ubiquitin ligases in immunity PN Moynagh Nature Reviews Immunology 14 (2), 122-131, 2014 | 127 | 2014 |
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis S Yang, B Wang, F Humphries, R Jackson, ME Healy, R Bergin, G Aviello, ... Nature immunology 14 (9), 927-936, 2013 | 114 | 2013 |