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Lee-ya Chu
Lee-ya Chu
在 crick.ac.uk 的电子邮件经过验证
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RNA recognition motifs of disease-linked RNA-binding proteins contribute to amyloid formation
S Agrawal, PH Kuo, LY Chu, B Golzarroshan, M Jain, HS Yuan
Scientific reports 9 (1), 6171, 2019
492019
Structural insights into RNA unwinding and degradation by RNase R
LY Chu, TJ Hsieh, B Golzarroshan, YP Chen, S Agrawal, HS Yuan
Nucleic acids research 45 (20), 12015-12024, 2017
462017
Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1
KW Huang, TC Liu, RY Liang, LY Chu, HL Cheng, JW Chu, YY Hsiao
PLoS biology 16 (5), e2005653, 2018
392018
Identification of inhibitors for the DEDDh family of exonucleases and a unique inhibition mechanism by crystal structure analysis of CRN-4 bound with 2-morpholin-4 …
KW Huang, KC Hsu, LY Chu, JM Yang, HS Yuan, YY Hsiao
Journal of medicinal chemistry 59 (17), 8019-8029, 2016
342016
Crystal structure of dimeric human PNPase reveals why disease-linked mutants suffer from low RNA import and degradation activities
B Golzarroshan, CL Lin, CL Li, WZ Yang, LY Chu, S Agrawal, HS Yuan
Nucleic acids research 46 (16), 8630-8640, 2018
222018
Structural insights into nanoRNA degradation by human Rexo2
LY Chu, S Agrawal, YP Chen, WZ Yang, HS Yuan
RNA 25 (6), 737-746, 2019
142019
Single cohesin molecules generate force by two distinct mechanisms
G Pobegalov, LY Chu, JM Peters, MI Molodtsov
Nature Communications 14 (1), 3946, 2023
72023
Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size
LY Chu, D Stedman, J Gannon, S Cox, G Pobegalov, MI Molodtsov
Nature Communications 15 (1), 9865, 2024
2024
Identification of inhibitors for the DEDDh family of exonucleases and a unique inhibition mechanism revealed by crystal structure analysis of CRN-4 bound with MES
YY Hsiao, KW Huang, KC Hsu, LY Chu, JM Yang, HS Yuan
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 72, 0-0, 2016
2016
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