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Yinnian Feng
Yinnian Feng
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
DK Das, Y Feng, RJ Mallis, X Li, DB Keskin, RE Hussey, SK Brady, ...
Proceedings of the National Academy of Sciences 112 (5), 1517-1522, 2015
2452015
Mechanosensing drives acuity of αβ T-cell recognition
Y Feng, KN Brazin, E Kobayashi, RJ Mallis, EL Reinherz, MJ Lang
Proceedings of the National Academy of Sciences 114 (39), E8204-E8213, 2017
1872017
αβ T cell receptor mechanosensing forces out serial engagement
Y Feng, EL Reinherz, MJ Lang
Trends in immunology 39 (8), 596-609, 2018
932018
Tuning T cell receptor sensitivity through catch bond engineering
X Zhao, EM Kolawole, W Chan, Y Feng, X Yang, MH Gee, KM Jude, ...
Science 376 (6589), eabl5282, 2022
692022
The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations
KN Brazin, RJ Mallis, A Boeszoermenyi, Y Feng, A Yoshizawa, PA Reche, ...
Immunity 49 (5), 829-841. e6, 2018
652018
Structural features of the αβTCR mechanotransduction apparatus that promote pMHC discrimination
KN Brazin, RJ Mallis, DK Das, Y Feng, W Hwang, J Wang, G Wagner, ...
Frontiers in immunology 6, 441, 2015
622015
Cellobiohydrolase 1 from Trichoderma reesei degrades cellulose in single cellobiose steps
SK Brady, S Sreelatha, Y Feng, SPS Chundawat, MJ Lang
Nature communications 6 (1), 10149, 2015
612015
Protamine-induced biosilica as efficient enzyme immobilization carrier with high loading and improved stability
L Li, Z Jiang, H Wu, Y Feng, J Li
Materials Science and Engineering: C 29 (6), 2029-2035, 2009
252009
MRBLES 2.0: High-throughput generation of chemically functionalized spectrally and magnetically encoded hydrogel beads using a simple single-layer microfluidic device
Y Feng, AK White, JB Hein, EA Appel, PM Fordyce
Microsystems & Nanoengineering 6 (1), 109, 2020
182020
A bead-based method for high-throughput mapping of the sequence-and force-dependence of T cell activation
Y Feng, X Zhao, AK White, KC Garcia, PM Fordyce
Nature Methods 19 (10), 1295-1305, 2022
172022
Selective crystal growth of theophylline-saccharin cocrystal on self-assembled monolayer from incongruent system
X Hou, Y Feng, P Zhang, H Wei, L Dang
Crystal Growth & Design 15 (10), 4918-4924, 2015
142015
Measuring αβ T-cell receptor-mediated mechanosensing using optical tweezers combined with fluorescence imaging
HM Stephens, KN Brazin, RJ Mallis, Y Feng, D Banik, EL Reinherz, ...
Optical Tweezers: Methods and Protocols, 727-753, 2022
52022
Analyzing Solution Complexation of Cocrystals by Mathematic Models and In-Situ ATR-FTIR Spectroscopy
Y Feng, L Dang, H Wei
Crystal growth & design 12 (4), 2068-2078, 2012
52012
A robotic microscope system to examine T cell receptor acuity against tumor neoantigens: a new tool for cancer immunotherapy research
LLS Ong, H Zhu, D Banik, Z Guan, Y Feng, EL Reinherz, MJ Lang, ...
IEEE Robotics and Automation Letters 4 (2), 1760-1767, 2019
42019
Phosphatase specificity principles uncovered by MRBLE: Dephos and global substrate identification
JB Hein, HT Nguyen, DH Garvanska, I Nasa, T Kruse, Y Feng, ...
Molecular Systems Biology 19 (12), e11782, 2023
32023
Structure-activity mapping of the peptide-and force-dependent landscape of T-cell activation
Y Feng, X Zhao, AK White, KC Garcia, PM Fordyce
Biorxiv, 2021.04. 24.441194, 2021
32021
“Build your own” ADC mimics: Identification of non-toxic linker/payload mimics for HIC-based DAR determination, high-throughput optimization, and continuous flow conjugation
C Bottecchia, MH Emmert, R Barrientos, Y Feng, D Holland-Moritz, ...
22024
Global substrate identification and high throughput in vitro dephosphorylation reactions uncover PP1 and PP2A-B55 specificity principles
JB Hein, HT Nguyen, DH Garvanska, I Nasa, Y Feng, BL Mendez, ...
bioRxiv, 2023.05. 14.540683, 2023
22023
“Build Your Own” ADC Mimics: Identification of Nontoxic Linker/Payload Mimics for HIC-Based DAR Determination, High-Throughput Optimization, and Continuous Flow Conjugation
MH Emmert, C Bottecchia, RC Barrientos, Y Feng, D Holland-Moritz, ...
Organic Process Research & Development, 2024
2024
High-throughput force-dependent cellular response assay using spectrally encoded smart beads
Y Feng, A White, PM Fordyce, X Zhao, KC Garcia
US Patent App. 18/250,723, 2023
2023
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