Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime DK Das, Y Feng, RJ Mallis, X Li, DB Keskin, RE Hussey, SK Brady, ... Proceedings of the National Academy of Sciences 112 (5), 1517-1522, 2015 | 245 | 2015 |
Mechanosensing drives acuity of αβ T-cell recognition Y Feng, KN Brazin, E Kobayashi, RJ Mallis, EL Reinherz, MJ Lang Proceedings of the National Academy of Sciences 114 (39), E8204-E8213, 2017 | 187 | 2017 |
αβ T cell receptor mechanosensing forces out serial engagement Y Feng, EL Reinherz, MJ Lang Trends in immunology 39 (8), 596-609, 2018 | 93 | 2018 |
Tuning T cell receptor sensitivity through catch bond engineering X Zhao, EM Kolawole, W Chan, Y Feng, X Yang, MH Gee, KM Jude, ... Science 376 (6589), eabl5282, 2022 | 69 | 2022 |
The T cell antigen receptor α transmembrane domain coordinates triggering through regulation of bilayer immersion and CD3 subunit associations KN Brazin, RJ Mallis, A Boeszoermenyi, Y Feng, A Yoshizawa, PA Reche, ... Immunity 49 (5), 829-841. e6, 2018 | 65 | 2018 |
Structural features of the αβTCR mechanotransduction apparatus that promote pMHC discrimination KN Brazin, RJ Mallis, DK Das, Y Feng, W Hwang, J Wang, G Wagner, ... Frontiers in immunology 6, 441, 2015 | 62 | 2015 |
Cellobiohydrolase 1 from Trichoderma reesei degrades cellulose in single cellobiose steps SK Brady, S Sreelatha, Y Feng, SPS Chundawat, MJ Lang Nature communications 6 (1), 10149, 2015 | 61 | 2015 |
Protamine-induced biosilica as efficient enzyme immobilization carrier with high loading and improved stability L Li, Z Jiang, H Wu, Y Feng, J Li Materials Science and Engineering: C 29 (6), 2029-2035, 2009 | 25 | 2009 |
MRBLES 2.0: High-throughput generation of chemically functionalized spectrally and magnetically encoded hydrogel beads using a simple single-layer microfluidic device Y Feng, AK White, JB Hein, EA Appel, PM Fordyce Microsystems & Nanoengineering 6 (1), 109, 2020 | 18 | 2020 |
A bead-based method for high-throughput mapping of the sequence-and force-dependence of T cell activation Y Feng, X Zhao, AK White, KC Garcia, PM Fordyce Nature Methods 19 (10), 1295-1305, 2022 | 17 | 2022 |
Selective crystal growth of theophylline-saccharin cocrystal on self-assembled monolayer from incongruent system X Hou, Y Feng, P Zhang, H Wei, L Dang Crystal Growth & Design 15 (10), 4918-4924, 2015 | 14 | 2015 |
Measuring αβ T-cell receptor-mediated mechanosensing using optical tweezers combined with fluorescence imaging HM Stephens, KN Brazin, RJ Mallis, Y Feng, D Banik, EL Reinherz, ... Optical Tweezers: Methods and Protocols, 727-753, 2022 | 5 | 2022 |
Analyzing Solution Complexation of Cocrystals by Mathematic Models and In-Situ ATR-FTIR Spectroscopy Y Feng, L Dang, H Wei Crystal growth & design 12 (4), 2068-2078, 2012 | 5 | 2012 |
A robotic microscope system to examine T cell receptor acuity against tumor neoantigens: a new tool for cancer immunotherapy research LLS Ong, H Zhu, D Banik, Z Guan, Y Feng, EL Reinherz, MJ Lang, ... IEEE Robotics and Automation Letters 4 (2), 1760-1767, 2019 | 4 | 2019 |
Phosphatase specificity principles uncovered by MRBLE: Dephos and global substrate identification JB Hein, HT Nguyen, DH Garvanska, I Nasa, T Kruse, Y Feng, ... Molecular Systems Biology 19 (12), e11782, 2023 | 3 | 2023 |
Structure-activity mapping of the peptide-and force-dependent landscape of T-cell activation Y Feng, X Zhao, AK White, KC Garcia, PM Fordyce Biorxiv, 2021.04. 24.441194, 2021 | 3 | 2021 |
“Build your own” ADC mimics: Identification of non-toxic linker/payload mimics for HIC-based DAR determination, high-throughput optimization, and continuous flow conjugation C Bottecchia, MH Emmert, R Barrientos, Y Feng, D Holland-Moritz, ... | 2 | 2024 |
Global substrate identification and high throughput in vitro dephosphorylation reactions uncover PP1 and PP2A-B55 specificity principles JB Hein, HT Nguyen, DH Garvanska, I Nasa, Y Feng, BL Mendez, ... bioRxiv, 2023.05. 14.540683, 2023 | 2 | 2023 |
“Build Your Own” ADC Mimics: Identification of Nontoxic Linker/Payload Mimics for HIC-Based DAR Determination, High-Throughput Optimization, and Continuous Flow Conjugation MH Emmert, C Bottecchia, RC Barrientos, Y Feng, D Holland-Moritz, ... Organic Process Research & Development, 2024 | | 2024 |
High-throughput force-dependent cellular response assay using spectrally encoded smart beads Y Feng, A White, PM Fordyce, X Zhao, KC Garcia US Patent App. 18/250,723, 2023 | | 2023 |