| Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines P Mesquita, N Jonckheere, R Almeida, MP Ducourouble, J Serpa, E Silva, ... Journal of Biological Chemistry 278 (51), 51549-51556, 2003 | 187 | 2003 |
| The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family N Skrypek, B Duchêne, M Hebbar, E Leteurtre, I Van Seuningen, ... Oncogene 32 (13), 1714-1723, 2013 | 173 | 2013 |
| The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers N Jonckheere, I Van Seuningen Biochimie 92 (1), 1-11, 2010 | 154 | 2010 |
| Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells AF Dessein, L Stechly, N Jonckheere, P Dumont, D Monté, E Leteurtre, ... Cancer research 70 (11), 4644-4654, 2010 | 138 | 2010 |
| Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells S Trehoux, F Lahdaoui, Y Delpu, F Renaud, E Leteurtre, J Torrisani, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (10), 2392-2403, 2015 | 134 | 2015 |
| Mucins and tumor resistance to chemotherapeutic drugs N Jonckheere, N Skrypek, I Van Seuningen Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1846 (1), 142-151, 2014 | 109 | 2014 |
| Mucins and pancreatic cancer N Jonckheere, N Skrypek, I Van Seuningen Cancers 2 (4), 1794-1812, 2010 | 102 | 2010 |
| Membrane-bound mucin modular domains: from structure to function N Jonckheere, N Skrypek, F Frénois, I Van Seuningen Biochimie 95 (6), 1077-1086, 2013 | 85 | 2013 |
| Overexpression of chemokine receptor CXCR 2 and ligand CXCL 7 in liver metastases from colon cancer is correlated to shorter disease‐free and overall survival T Desurmont, N Skrypek, A Duhamel, N Jonckheere, G Millet, E Leteurtre, ... Cancer science 106 (3), 262-269, 2015 | 83 | 2015 |
| The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting N Jonckheere, R Vasseur, I Van Seuningen Critical reviews in oncology/hematology 111, 7-19, 2017 | 82 | 2017 |
| The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42–44 MAPK, Akt, Bcl-2 and MMP13 pathways S Tréhoux, B Duchêne, N Jonckheere, I Van Seuningen Biochemical and biophysical research communications 456 (3), 757-762, 2015 | 80 | 2015 |
| A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-β in pancreatic carcinogenesis N Jonckheere, M Perrais, C Mariette, SK Batra, JP Aubert, P Pigny, ... Oncogene 23 (34), 5729-5738, 2004 | 77 | 2004 |
| miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer F Lahdaoui, Y Delpu, A Vincent, F Renaud, M Messager, B Duchêne, ... Oncogene 34 (6), 780-788, 2015 | 72 | 2015 |
| The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells M van Der Sluis, MHM Melis, N Jonckheere, MP Ducourouble, HA Büller, ... Biochemical and biophysical research communications 325 (3), 952-960, 2004 | 72 | 2004 |
| The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance … N Skrypek, R Vasseur, A Vincent, B Duchêne, I Van Seuningen, ... Oncotarget 6 (13), 10853, 2015 | 68 | 2015 |
| The Mucin MUC4 and Its Membrane Partner ErbB2 Regulate Biological Properties of Human CAPAN-2 Pancreatic Cancer Cells via Different Signalling Pathways N Jonckheere, N Skrypek, J Merlin, AF Dessein, P Dumont, E Leteurtre, ... PLoS One 7 (2), e32232, 2012 | 67 | 2012 |
| Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1α G Piessen, N Jonckheere, A Vincent, B Hémon, MP Ducourouble, ... Biochemical Journal 402 (1), 81-91, 2007 | 67 | 2007 |
| Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase … C Mariette, M Perrais, E Leteurtre, N Jonckheere, B Hémon, P Pigny, ... Biochemical Journal 377 (3), 701-708, 2004 | 62 | 2004 |
| The membrane-bound mucins: how large O-glycoproteins play key roles in epithelial cancers and hold promise as biological tools for gene-based and immunotherapies N Jonckheere, I Van Seuningen Critical Reviews™ in Oncogenesis 14 (2-3), 2008 | 61 | 2008 |
| Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in … N Jonckheere, I Van Seuningen Journal of translational medicine 16, 1-22, 2018 | 58 | 2018 |
