Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein LM Longo, J Lee, M Blaber Proceedings of the National Academy of Sciences 110 (6), 2135-2139, 2013 | 108 | 2013 |
A bird’s-eye view of enzyme evolution: chemical, physicochemical, and physiological considerations D Davidi, LM Longo, J Jabłońska, R Milo, DS Tawfik Chemical reviews 118 (18), 8786-8797, 2018 | 100 | 2018 |
Protein design at the interface of the pre-biotic and biotic worlds LM Longo, M Blaber Archives of biochemistry and biophysics 526 (1), 16-21, 2012 | 83 | 2012 |
On the emergence of P-Loop NTPase and Rossmann enzymes from a Beta-Alpha-Beta ancestral fragment LM Longo, J Jabłońska, P Vyas, M Kanade, R Kolodny, N Ben-Tal, ... Elife 9, e64415, 2020 | 70 | 2020 |
Primordial emergence of a nucleic acid binding protein via phase separation and statistical ornithine to arginine conversion LM Longo, D Despotović, O Weil-Ktorza, MJ Walker, J Jabłońska, ... Proceedings of the National Academy of Sciences 117 (27), 15731-15739, 2020 | 63 | 2020 |
Characterization of binding of LARP6 to the 5’stem-loop of collagen mRNAs: implications for synthesis of type I collagen L Stefanovic, L Longo, Y Zhang, B Stefanovic RNA biology 11 (11), 1386-1401, 2014 | 47 | 2014 |
A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J Lee, VK Dubey, LM Longo, M Blaber J Mol Biol 377 (4), 1251-1264, 2008 | 38 | 2008 |
Bacterial wilt induced changes in nutrient distribution and biomass and the effect of acibenzolar-S-methyl on bacterial wilt in tomato G Hacisalihoglu, P Ji, LM Longo, S Olson, TM Momol Crop Protection 26 (7), 978-982, 2007 | 35 | 2007 |
Short and simple sequences favored the emergence of N-helix phospho-ligand binding sites in the first enzymes LM Longo, D Petrović, SCL Kamerlin, DS Tawfik Proceedings of the National Academy of Sciences 117 (10), 5310-5318, 2020 | 33 | 2020 |
Experimental support for the foldability–function tradeoff hypothesis: Segregation of the folding nucleus and functional regions in fibroblast growth factor‐1 L Longo, J Lee, M Blaber Protein Science 21 (12), 1911-1920, 2012 | 32 | 2012 |
Prebiotic protein design supports a halophile origin of foldable proteins LM Longo, M Blaber Frontiers in microbiology 4, 418, 2014 | 29 | 2014 |
Peptide-RNA coacervates as a cradle for the evolution of folded domains M Seal, O Weil-Ktorza, D Despotovic, DS Tawfik, Y Levy, N Metanis, ... Journal of the American Chemical Society 144 (31), 14150-14160, 2022 | 27 | 2022 |
Mutation choice to eliminate buried free cysteines in protein therapeutics X Xia, LM Longo, M Blaber Journal of pharmaceutical sciences 104 (2), 566-576, 2015 | 27 | 2015 |
Evolution and design of protein structure by folding nucleus symmetric expansion LM Longo, OS Kumru, CR Middaugh, M Blaber Structure 22 (10), 1377-1384, 2014 | 25* | 2014 |
Differential response of common bean genotypes to mycorrhizal colonization G Hacisalihoglu, ER Duke, LM Longo Proceedings of the Florida State Horticultural Society 118, 150-152, 2005 | 25 | 2005 |
Polyamines mediate folding of primordial hyperacidic helical proteins D Despotović, LM Longo, E Aharon, A Kahana, T Scherf, I Gruic-Sovulj, ... Biochemistry 59 (46), 4456-4462, 2020 | 23 | 2020 |
Evolution of a protein folding nucleus X Xia, LM Longo, MA Sutherland, M Blaber Protein Science 25 (7), 1227-1240, 2016 | 23 | 2016 |
Bacilli glutamate dehydrogenases diverged via coevolution of transcription and enzyme regulation L Noda‐Garcia, ML Romero Romero, LM Longo, I Kolodkin‐Gal, ... EMBO reports 18 (7), 1139-1149, 2017 | 22 | 2017 |
Emergence of symmetric protein architecture from a simple peptide motif: evolutionary models M Blaber, J Lee, L Longo Cellular and Molecular Life Sciences 69 (23), 3999-4006, 2012 | 21 | 2012 |
A single aromatic core mutation converts a designed “primitive” protein from halophile to mesophile folding LM Longo, CA Tenorio, OS Kumru, CR Middaugh, M Blaber Protein Science 24 (1), 27-37, 2015 | 20 | 2015 |