| Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice C Léon, B Hechler, M Freund, A Eckly, C Vial, P Ohlmann, A Dierich, ... The Journal of clinical investigation 104 (12), 1731-1737, 1999 | 571 | 1999 |
| The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells C Léon, B Hechler, C Vial, C Leray, JP Cazenave, C Gachet FEBS letters 403 (1), 26-30, 1997 | 386 | 1997 |
| Migrating platelets are mechano-scavengers that collect and bundle bacteria F Gaertner, Z Ahmad, G Rosenberger, S Fan, L Nicolai, B Busch, G Yavuz, ... Cell 171 (6), 1368-1382. e23, 2017 | 340 | 2017 |
| The P2Y1 Receptor Is Necessary for Adenosine 5′-Diphosphate–Induced Platelet Aggregation B Hechler, C Léon, C Vial, P Vigne, C Frelin, JP Cazenave, C Gachet Blood, The Journal of the American Society of Hematology 92 (1), 152-159, 1998 | 338 | 1998 |
| Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity T Moriyama, T Iida, K Kobayashi, T Higashi, T Fukuoka, H Tsumura, ... Journal of Neuroscience 23 (14), 6058-6062, 2003 | 280 | 2003 |
| Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion C Léon, A Eckly, B Hechler, B Aleil, M Freund, C Ravanat, M Jourdain, ... Blood, The Journal of the American Society of Hematology 110 (9), 3183-3191, 2007 | 212 | 2007 |
| Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist A Baurand, P Raboisson, M Freund, C Léon, JP Cazenave, ... European journal of pharmacology 412 (3), 213-221, 2001 | 194 | 2001 |
| The P2Y12 receptor induces platelet aggregation through weak activation of the αIIbβ3 integrin–a phosphoinositide 3-kinase-dependent mechanism G Kauffenstein, W Bergmeier, A Eckly, P Ohlmann, C Leon, JP Cazenave, ... FEBS letters 505 (2), 281-290, 2001 | 188 | 2001 |
| Platelet ADP receptors contribute to the initiation of intravascular coagulation C Leon, M Alex, A Klocke, E Morgenstern, C Moosbauer, A Eckly, ... Blood 103 (2), 594-600, 2004 | 182 | 2004 |
| RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization L Lordier, D Bluteau, A Jalil, C Legrand, J Pan, P Rameau, D Jouni, ... Nature communications 3 (1), 717, 2012 | 180 | 2012 |
| Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells JW Shin, A Buxboim, KR Spinler, J Swift, DA Christian, CA Hunter, C Léon, ... Cell stem cell 14 (1), 81-93, 2014 | 177 | 2014 |
| ATP derivatives are antagonists of the P2Y1 receptor: similarities to the platelet ADP receptor B Hechler, P Vigne, C Léon, JP Breittmayer, C Gachet, C Frelin Molecular Pharmacology 53 (4), 727-733, 1998 | 177 | 1998 |
| Differential Involvement of the P2Y1 and P2Y12 Receptors in Platelet Procoagulant Activity C Léon, C Ravanat, M Freund, JP Cazenave, C Gachet Arteriosclerosis, thrombosis, and vascular biology 23 (10), 1941-1947, 2003 | 171 | 2003 |
| Activation of ADP receptors and platelet function C Gachet, B Hechlel, C Léon, C Vial, C Leray, P Ohlmann, JP Cazenave Thrombosis and haemostasis 78 (07), 271-275, 1997 | 169 | 1997 |
| Key Role of the P2Y1 Receptor in Tissue Factor–Induced Thrombin-Dependent Acute Thromboembolism: Studies in P2Y1-Knockout Mice and Mice Treated With a P2Y1 Antagonist C Léon, M Freund, C Ravanat, A Baurand, JP Cazenave, C Gachet Circulation 103 (5), 718-723, 2001 | 167 | 2001 |
| Biogenesis of the demarcation membrane system (DMS) in megakaryocytes A Eckly, H Heijnen, F Pertuy, W Geerts, F Proamer, JY Rinckel, C Léon, ... Blood, The Journal of the American Society of Hematology 123 (6), 921-930, 2014 | 166 | 2014 |
| Desensitization of the platelet aggregation response to ADP: differential down-regulation of the P2Y1 and P2cyc receptors A Baurand, A Eckly, N Bari, C Léon, B Hechler, JP Cazenave, C Gachet Thrombosis and haemostasis 84 (09), 484-491, 2000 | 161 | 2000 |
| Presence of P2X1 purinoceptors in human platelets and megakaryoblastic cell lines C Vial, B Hechier, C Léon, JP Cazenave, C Gachet Thrombosis and haemostasis 78 (12), 1500-1504, 1997 | 134 | 1997 |
| Inhibition of localized thrombosis in P2Y1-deficient mice and rodents treated with MRS2179, a P2Y1 receptor antagonist N Lenain, M Freund, C Leon, JP Cazenave, C Gachet Journal of Thrombosis and Haemostasis 1 (6), 1144-1149, 2003 | 131 | 2003 |
| Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane H Schachtner, SDJ Calaminus, A Sinclair, J Monypenny, MP Blundell, ... Blood, The Journal of the American Society of Hematology 121 (13), 2542-2552, 2013 | 127 | 2013 |
